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Abstract

New Delhi metallo-beta-lactamase (NDM)-producing () ST147 caused a large multi-hospital outbreak in Italy from 2018 to 2021. We describe a new ST6668 NDM-producing clone, belonging to CC147, which rapidly spread across hospitals in the Pavia province (Northern Italy) from February to August 2023. Genomic analyses revealed that ST6668 is different from ST147 and fast evolving. As shown here, genomic surveillance programmes are useful for tracking the spread of new clones with reduced susceptibility to most antibiotics.

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/content/10.2807/1560-7917.ES.2023.28.42.2300522
2023-10-19
2024-12-30
/content/10.2807/1560-7917.ES.2023.28.42.2300522
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Rapid spread of a novel NDM-producing clone of Klebsiella pneumoniae CC147, Northern Italy, February to August 2023
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Irene+Mileto&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mileto Irene</a>, <a href="/search?value1=Greta+Petazzoni&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Petazzoni Greta</a>, <a href="/search?value1=Marta+Corbella&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Corbella Marta</a>, <a href="/search?value1=Stefano+Gaiarsa&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gaiarsa Stefano</a>, <a href="/search?value1=Cristina+Merla&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Merla Cristina</a>, <a href="/search?value1=Angela+Kuka&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kuka Angela</a>, <a href="/search?value1=Marina+Ramus&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ramus Marina</a>, <a href="/search?value1=Cristina+Terulla&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Terulla Cristina</a>, <a href="/search?value1=Micaela+Brandolini&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Brandolini Micaela</a>, <a href="/search?value1=Antonio+Piralla&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Piralla Antonio</a>, <a href="/search?value1=Patrizia+Cambieri&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cambieri Patrizia</a>, <a href="/search?value1=Fausto+Baldanti&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Baldanti Fausto</a></span>. Rapid spread of a novel NDM-producing clone of Klebsiella pneumoniae CC147, Northern Italy, February to August 2023. <a href="/content/ecdc">Euro Surveill.</a> 2023;28(42):pii=2300522. <a href="https://doi.org/10.2807/1560-7917.ES.2023.28.42.2300522" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2023.28.42.2300522</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 01 Oct 2023;&nbsp;&nbsp; <span class="generated">Accepted</span>: 18 Oct 2023 </span> </p>
/content/10.2807/1560-7917.ES.2023.28.42.2300522
/content/10.2807/1560-7917.ES.2023.28.42.2300522
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