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Abstract

We estimated interim influenza A vaccine effectiveness (VE) following a late sharp rise in cases during an influenza A(H3N2)-dominated 2021/22 season, after lifting COVID-19 restrictions. In children aged 2–6 years offered a live attenuated influenza vaccine, adjusted VE was 62.7% (95% CI: 10.9–84.4) in hospitalised and 64.2% (95% CI: 50.5–74.1) in non-hospitalised children. In non-hospitalised patients aged 7–44 years, VE was 24.8% (95% CI: 12.8–35.2); VE was non-significant in remaining age groups and hospital/non-hospital settings.

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/content/10.2807/1560-7917.ES.2022.27.15.2200278
2022-04-14
2024-12-26
/content/10.2807/1560-7917.ES.2022.27.15.2200278
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A late sharp increase in influenza detections and low interim vaccine effectiveness against the circulating A(H3N2) strain, Denmark, 2021/22 influenza season up to 25 March 2022
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Hanne-Dorthe+Emborg&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Emborg Hanne-Dorthe</a>, <a href="/search?value1=Lasse+S+Vestergaard&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Vestergaard Lasse S</a>, <a href="/search?value1=Amanda+Bolt+Botnen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Botnen Amanda Bolt</a>, <a href="/search?value1=Jens+Nielsen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nielsen Jens</a>, <a href="/search?value1=Tyra+G+Krause&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Krause Tyra G</a>, <a href="/search?value1=Ramona+Trebbien&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Trebbien Ramona</a></span>. A late sharp increase in influenza detections and low interim vaccine effectiveness against the circulating A(H3N2) strain, Denmark, 2021/22 influenza season up to 25 March 2022. <a href="/content/ecdc">Euro Surveill.</a> 2022;27(15):pii=2200278. <a href="https://doi.org/10.2807/1560-7917.ES.2022.27.15.2200278" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2022.27.15.2200278</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 31 Mar 2022;&nbsp;&nbsp; <span class="generated">Accepted</span>: 12 Apr 2022 </span> </p>
/content/10.2807/1560-7917.ES.2022.27.15.2200278
/content/10.2807/1560-7917.ES.2022.27.15.2200278
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