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Abstract

A nosocomial outbreak of SARS-CoV-2 Delta variant infected 42 patients, staff and family members; 39 were fully vaccinated. The attack rate was 10.6% (16/151) among exposed staff and reached 23.7% (23/97) among exposed patients in a highly vaccinated population, 16–26 weeks after vaccination (median: 25 weeks). All cases were linked and traced to one patient. Several transmissions occurred between individuals wearing face masks. Fourteen of 23 patients became severely sick or died, raising a question about possible waning immunity.

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/content/10.2807/1560-7917.ES.2021.26.39.2100822
2021-09-30
2024-11-23
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2021.26.39.2100822
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References

  1. Ministry of Health. Israel COVID-19 data tracker [Accessed 16 Aug 2021]. Jerusalem: Ministry of Health. Available from: https://www.gov.il/en/departments/guides/information-corona
  2. Dagan N, Barda N, Kepten E, Miron O, Perchik S, Katz MA, et al. BNT162b2 mRNA Covid-19 vaccine in a nationwide mass vaccination setting. N Engl J Med. 2021;384(15):1412-23.  https://doi.org/10.1056/NEJMoa2101765  PMID: 33626250 
  3. Nextstrain. All SARS-CoV-2 datasets. [Accessed: 17 Sep 2021]. Available from: https://nextstrain.org/sars-cov-2/#datasets
  4. Centers for Disease Control and Prevention (CDC). COVID-19: SARS-CoV-2 variant classifications and definitions. Atlanta: CDC. [Accessed: 15 Aug 2021]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/variants/variant-info.html
  5. Ministry of Health. Vaccination guidelines for recovered individuals. Jerusalem: Ministry of Health. [Accessed: 18 Mar 2021]. Hebrew. Available from: https://www.health.gov.il/UnitsOffice/HD/PH/epidemiology/td/286116521.pdf
  6. Zuckerman NS, Pando R, Bucris E, Drori Y, Lustig Y, Erster O, et al. Comprehensive analyses of SARS-CoV-2 transmission in a public health virology laboratory. Viruses. 2020;12(8):E854.  https://doi.org/10.3390/v12080854  PMID: 32764372 
  7. Elbe S, Buckland-Merrett G. Data, disease and diplomacy: GISAID’s innovative contribution to global health. Glob Chall. 2017;1(1):33-46.  https://doi.org/10.1002/gch2.1018  PMID: 31565258 
  8. Hadfield J, Megill C, Bell SM, Huddleston J, Potter B, Callender C, et al. Nextstrain: real-time tracking of pathogen evolution. Bioinformatics. 2018;34(23):4121-3.  https://doi.org/10.1093/bioinformatics/bty407  PMID: 29790939 
  9. Lopez Bernal J, Andrews N, Gower C, Gallagher E, Simmons R, Thelwall S, et al. Effectiveness of Covid-19 vaccines against the B.1.617.2 (Delta) variant. N Engl J Med. 2021;385(7):585-94.  https://doi.org/10.1056/NEJMoa2108891  PMID: 34289274 
  10. Brown CM, Vostok J, Johnson H, Burns M, Gharpure R, Sami S, et al. Outbreak of SARS-CoV-2 infections, including COVID-19 vaccine breakthrough infections, associated with large public gatherings - Barnstable County, Massachusetts, July 2021. MMWR Morb Mortal Wkly Rep. 2021;70(31):1059-62.  https://doi.org/10.15585/mmwr.mm7031e2  PMID: 34351882 
  11. Dougherty K, Mannell M, Naqvi O, Matson D, Stone J. SARS-CoV-2 B.1.617.2 (Delta) variant COVID-19 outbreak associated with a gymnastics facility - Oklahoma, April-May 2021. MMWR Morb Mortal Wkly Rep. 2021;70(28):1004-7.  https://doi.org/10.15585/mmwr.mm7028e2  PMID: 34264910 
  12. Hetemäki I, Kääriäinen S, Alho P, Mikkola J, Savolainen-Kopra C, Ikonen N, et al. An outbreak caused by the SARS-CoV-2 Delta variant (B.1.617.2) in a secondary care hospital in Finland, May 2021. Euro Surveill. 2021;26(30):2100636.  https://doi.org/10.2807/1560-7917.ES.2021.26.30.2100636  PMID: 34328076 
  13. Bar-On YM, Goldberg Y, Mandel M, Bodenheimer O, Freedman L, Kalkstein N, et al. BNT162b2 vaccine booster dose protection: A nationwide study from Israel. medRxiv. 2021.08.27.21262679. Preprint. https://doi.org/10.1101/2021.08.27.21262679
  14. Goldberg Y, Mandel M, Bar-On YM, Bodenheimer O, Freedman LS, Haas E, et al. Waning immunity of the BNT162b2 vaccine: A nationwide study from Israel. medRxiv. 2021.08.24.21262423. Preprint. https://doi.org/10.1101/2021.08.24.21262423
Nosocomial outbreak caused by the SARS-CoV-2 Delta variant in a highly vaccinated population, Israel, July 2021
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Pnina+Shitrit&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Shitrit Pnina</a>, <a href="/search?value1=Neta+S+Zuckerman&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Zuckerman Neta S</a>, <a href="/search?value1=Orna+Mor&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mor Orna</a>, <a href="/search?value1=Bat-Sheva+Gottesman&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gottesman Bat-Sheva</a>, <a href="/search?value1=Michal+Chowers&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Chowers Michal</a></span>. Nosocomial outbreak caused by the SARS-CoV-2 Delta variant in a highly vaccinated population, Israel, July 2021. <a href="/content/ecdc">Euro Surveill.</a> 2021;26(39):pii=2100822. <a href="https://doi.org/10.2807/1560-7917.ES.2021.26.39.2100822" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2021.26.39.2100822</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 24 Aug 2021;&nbsp;&nbsp; <span class="generated">Accepted</span>: 23 Sept 2021 </span> </p>
/content/10.2807/1560-7917.ES.2021.26.39.2100822
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