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Abstract

Antibody-screening methods to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) need to be validated. We evaluated SARS-CoV-2 IgG and IgA ELISAs in conjunction with the EUROLabworkstation (Euroimmun, Lübeck, Germany). Overall specificities were 91.9% and 73.0% for IgG and IgA ELISAs, respectively. Of 39 coronavirus disease patients, 13 were IgG and IgA positive and 11 IgA alone at sampling. IgGs and IgAs were respectively detected at a median of 12 and 11 days after symptom onset.

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/content/10.2807/1560-7917.ES.2020.25.18.2000603
2020-05-07
2024-11-21
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2020.25.18.2000603
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Evaluation of commercial and automated SARS-CoV-2 IgG and IgA ELISAs using coronavirus disease (COVID-19) patient samples
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Anne+J+J%C3%A4%C3%A4skel%C3%A4inen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Jääskeläinen Anne J</a>, <a href="/search?value1=Eliisa+Kek%C3%A4l%C3%A4inen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kekäläinen Eliisa</a>, <a href="/search?value1=Hannimari+Kallio-Kokko&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kallio-Kokko Hannimari</a>, <a href="/search?value1=Laura+Mannonen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mannonen Laura</a>, <a href="/search?value1=Elisa+Kortela&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kortela Elisa</a>, <a href="/search?value1=Olli+Vapalahti&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Vapalahti Olli</a>, <a href="/search?value1=Satu+Kurkela&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kurkela Satu</a>, <a href="/search?value1=Maija+Lappalainen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lappalainen Maija</a></span>. Evaluation of commercial and automated SARS-CoV-2 IgG and IgA ELISAs using coronavirus disease (COVID-19) patient samples. <a href="/content/ecdc">Euro Surveill.</a> 2020;25(18):pii=2000603. <a href="https://doi.org/10.2807/1560-7917.ES.2020.25.18.2000603" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2020.25.18.2000603</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 12 Apr 2020;&nbsp;&nbsp; <span class="generated">Accepted</span>: 07 May 2020 </span> </p>
/content/10.2807/1560-7917.ES.2020.25.18.2000603
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