Laboratory capability for molecular detection and confirmation of novel coronavirus in Europe, November 2012

D Palm; D Pereyaslov; J Vaz; E Broberg; H Zeller; D Gross; C S Brown; M J Struelens; on behalf of the Joint ECDC-WHO Regional Office for Europe Novel Coronavirus Laboratory Survey participants; ECDC National Microbiology Focal Points, WHO European Region EuroFlu Network and European Network for Diagnostics of

doi:10.2807/ese.17.49.20335-en

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Laboratory capability for molecular detection and confirmation of novel coronavirus in Europe, November 2012
D Palm¹ , D Pereyaslov² , J Vaz¹ , E Broberg¹ , H Zeller¹ , D Gross² , C S Brown² , M J Struelens¹ , on behalf of the Joint ECDC-WHO Regional Office for Europe Novel Coronavirus Laboratory Survey participants; ECDC National Microbiology Focal Points, WHO European Region EuroFlu Network and European Network for Diagnostics of "Imported" Viral Diseases (ENIVD)³
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Affiliations: ¹ European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden ² World Health Organization (WHO) Regional Office for Europe, Copenhagen, Denmark ³ Joint ECDC-WHO Regional Office for Europe Novel Coronavirus Laboratory Survey participants; ECDC National Microbiology Focal Points, WHO European Region EuroFlu Network and European Network for Diagnostics of "Imported" Viral Diseases (ENIVD)

Correspondence:
M Struelens
marc.struelens ecdc.europa.eu
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Citation style for this article: Palm D, Pereyaslov D, Vaz J, Broberg E, Zeller H, Gross D, Brown C S, Struelens M J, on behalf of the Joint ECDC-WHO Regional Office for Europe Novel Coronavirus Laboratory Survey participants; ECDC National Microbiology Focal Points, WHO European Region EuroFlu Network and European Network for Diagnostics of "Imported" Viral Diseases (ENIVD). Laboratory capability for molecular detection and confirmation of novel coronavirus in Europe, November 2012. Euro Surveill. 2012;17(49):pii=20335. https://doi.org/10.2807/ese.17.49.20335-en Received: 05 Dec 2012

Abstract

A rapid survey by the European Centre for Disease Prevention and Control (ECDC) and the World Health Organization (WHO) Regional Office for Europe ascertained the availability of national reference laboratory testing for a recently detected novel coronavirus as of 28 November 2012. Screening by internal quality controlled upE-RT-PCR assay was available in 23/46 of responding countries in the WHO European Region, of which 19/30 in European Union (EU) and European Economic Area (EEA) countries. Confirmation of positive screened samples by either ORF1b - RT-PCR, or other target RT-PCR assays with sequence analysis or whole-genome sequence analysis was available in 22/46 responding countries of which 18/30 in EU/EEA countries.