Large and ongoing outbreak of haemolytic uraemic syndrome, Germany, May 2011

C Frank; M S Faber; M Askar; H Bernard; A Fruth; A Gilsdorf; M Höhle; H Karch; G Krause; R Prager; A Spode; K Stark; D Werber; HUS investigation team

doi:10.2807/ese.16.21.19878-en

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Large and ongoing outbreak of haemolytic uraemic syndrome, Germany, May 2011
C Frank^1,2 , M S Faber^1,2 , M Askar^1,3,4 , H Bernard¹ , A Fruth⁵ , A Gilsdorf¹ , M Höhle¹ , H Karch⁶ , G Krause¹ , R Prager⁵ , A Spode⁷ , K Stark¹ , D Werber¹ , HUS investigation team⁸
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Affiliations: ¹ Robert Koch Institute, Berlin, Germany ² These authors contributed equally to the manuscript ³ Postgraduate Training for Applied Epidemiology (PAE, German Field Epidemiology Training Programme), Robert Koch Institute, Department for Infectious Disease Epidemiology, Berlin, Germany ⁴ European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden ⁵ National Reference Centre for Salmonella and other bacterial enteric pathogens at the RKI, Wernigerode, Germany ⁶ Consulting laboratory for haemolytic uraemic syndrome, Institute of Hygiene, University of Münster, Germany ⁷ Local health department Hamburg Nord, Hamburg, Germany ⁸ The members of the team are listed at the end of the article

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M Faber
FaberM rki.de
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Citation style for this article: Frank C, Faber M S, Askar M, Bernard H, Fruth A, Gilsdorf A, Höhle M, Karch H, Krause G, Prager R, Spode A, Stark K, Werber D, HUS investigation team. Large and ongoing outbreak of haemolytic uraemic syndrome, Germany, May 2011. Euro Surveill. 2011;16(21):pii=19878. https://doi.org/10.2807/ese.16.21.19878-en Received: 26 May 2011

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Abstract

Since early May 2011, an increased incidence of haemolytic uraemic syndrome (HUS) and bloody diarrhoea related to infections with Shiga toxin-producing Escherichia coli (STEC) has been observed in Germany, with most cases in the north of the country. Cases reported from other European countries had travelled to this area. First results of a case-control study conducted in Hamburg suggest an association between the occurrence of disease and the consumption of raw tomatoes, cucumber and leaf salad. .