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Abstract

During the 2024/25 influenza season, enhanced and standard-dose influenza vaccines were available for individuals aged 65 and older. Compared with the standard-dose quadrivalent influenza vaccine (QIV), the adjuvanted QIV was significantly more effective, with an overall vaccine effectiveness (VE) of 48% (95% CI: 42–52) vs 33% (95% CI: 24–41) when considering both non-hospitalised and hospitalised patients. The high-dose QIV demonstrated similar effectiveness to the adjuvanted QIV. These findings support the inclusion of enhanced influenza vaccines in future vaccination programmes.

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/content/10.2807/1560-7917.ES.2025.30.12.2500174
2025-03-27
2025-04-01
/content/10.2807/1560-7917.ES.2025.30.12.2500174
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References

  1. Schønning K, Dessau RB, Jensen TG, Thorsen NM, Wiuff C, Nielsen L, et al. Electronic reporting of diagnostic laboratory test results from all healthcare sectors is a cornerstone of national preparedness and control of COVID-19 in Denmark. APMIS. 2021;129(7):438-51.  https://doi.org/10.1111/apm.13140  PMID: 33949007 
  2. World Health Organization (WHO). Recommended composition of influenza virus vaccines for use in the 2024-2025 northern hemisphere influenza season. Geneva: WHO; 2024. Available from: https://cdn.who.int/media/docs/default-source/influenza/who-influenza-recommendations/vcm-northern-hemisphere-recommendation-2024-2025/recommended-composition-of-influenza-virus-vaccines-for-use-in-the-2024-2025-northern-hemisphere-influenza-season.pdf?sfvrsn=2e9d2194_7&download=true
  3. Grove Krause T, Jakobsen S, Haarh M, Mølbak K. The Danish vaccination register. Euro Surveill. 2012;17(17):2.  https://doi.org/10.2807/ese.17.17.20155-en  PMID: 22551494 
  4. Lynge E, Sandegaard JL, Rebolj M. The Danish national patient register. Scand J Public Health. 2011;39(7) Suppl;30-3.  https://doi.org/10.1177/1403494811401482  PMID: 21775347 
  5. Emborg HD, Vestergaard LS, Botnen AB, Nielsen J, Krause TG, Trebbien R. A late sharp increase in influenza detections and low interim vaccine effectiveness against the circulating A(H3N2) strain, Denmark, 2021/22 influenza season up to 25 March 2022. Euro Surveill. 2022;27(15):2200278.  https://doi.org/10.2807/1560-7917.ES.2022.27.15.2200278  PMID: 35426361 
  6. Kissling E, Maurel M, Emborg HD, Whitaker H, McMenamin J, Howard J, et al. Interim 2022/23 influenza vaccine effectiveness: six European studies, October 2022 to January 2023. Euro Surveill. 2023;28(21):2300116.  https://doi.org/10.2807/1560-7917.ES.2023.28.21.2300116  PMID: 37227299 
  7. Rose AM, Lucaccioni H, Marsh K, Kirsebom F, Whitaker H, Emborg HD, et al. Interim 2024/25 influenza vaccine effectiveness: eight European studies, September 2024 to January 2025. Euro Surveill. 2025;30(7):2500102.  https://doi.org/10.2807/1560-7917.ES.2025.30.7.2500102  PMID: 39980423 
  8. Separovic L, Zhan Y, Kaweski SE, Sabaiduc S, Carazo S, Olsha R, et al. Interim estimates of vaccine effectiveness against influenza A(H1N1)pdm09 and A(H3N2) during a delayed influenza season, Canada, 2024/25. Euro Surveill. 2025;30(4):2500059.  https://doi.org/10.2807/1560-7917.ES.2025.30.4.2500059  PMID: 39885824 
Enhanced influenza vaccines impact effectiveness in individuals aged 65 years and older, Denmark, 2024/25 influenza season up to 4 March 2025
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Hanne-Dorthe+Emborg&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Emborg Hanne-Dorthe</a>, <a href="/search?value1=Palle+Valentiner-Branth&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Valentiner-Branth Palle</a>, <a href="/search?value1=Ramona+Trebbien&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Trebbien Ramona</a>, <a href="/search?value1=Amanda+Bolt+Botnen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bolt Botnen Amanda</a>, <a href="/search?value1=Tyra+Grove+Krause&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Grove Krause Tyra</a>, <a href="/search?value1=Bolette+S%C3%B8borg&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Søborg Bolette</a></span>. Enhanced influenza vaccines impact effectiveness in individuals aged 65 years and older, Denmark, 2024/25 influenza season up to 4 March 2025. <a href="/content/ecdc">Euro Surveill.</a> 2025;30(12):pii=2500174. <a href="https://doi.org/10.2807/1560-7917.ES.2025.30.12.2500174" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2025.30.12.2500174</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 12 Mar 2025;&nbsp;&nbsp; <span class="generated">Accepted</span>: 25 Mar 2025 </span> </p>
/content/10.2807/1560-7917.ES.2025.30.12.2500174
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