Interim 2023/24 influenza A vaccine effectiveness: VEBIS European primary care and hospital multicentre studies, September 2023 to January 2024

Marine Maurel; Jennifer Howard; Esther Kissling; Francisco Pozo; Gloria Pérez-Gimeno; Silke Buda; Noémie Sève; Adele McKenna; Adam Meijer; Ana Paula Rodrigues; Iván Martínez-Baz; Ivan Mlinarić; Neus Latorre-Margalef; Gergő Túri; Mihaela Lazăr; Clara Mazagatos; Aitziber Echeverria; Stephen Abela; Marc Bourgeois; Ausenda Machado; Ralf Dürrwald; Goranka Petrović; Beatrix Oroszi; Ligita Jancoriene; Alexandru Marin; Petr Husa; Roisin Duffy; Frederika Dijkstra; Virtudes Gallardo García; Luise Goerlitz; Vincent Enouf; Charlene Bennett; Mariëtte Hooiveld; Raquel Guiomar; Camino Trobajo-Sanmartín; Vesna Višekruna Vučina; Tove Samuelsson Hagey; Ana Sofía Lameiras Azevedo; Jesús Castilla; Gerd Xuereb; Bénédicte Delaere; Verónica Gómez; Kristin Tolksdorf; Sabrina Bacci; Nathalie Nicolay; Marlena Kaczmarek; Angela MC Rose; on behalf of the European IVE group

doi:10.2807/1560-7917.ES.2024.29.8.2400089

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Interim 2023/24 influenza A vaccine effectiveness: VEBIS European primary care and hospital multicentre studies, September 2023 to January 2024
Marine Maurel^1,* , Jennifer Howard^1,* , Esther Kissling¹ , Francisco Pozo^2,3 , Gloria Pérez-Gimeno^3,4 , Silke Buda⁵ , Noémie Sève⁶ , Adele McKenna⁷ , Adam Meijer⁸ , Ana Paula Rodrigues⁹ , Iván Martínez-Baz¹⁰ , Ivan Mlinarić¹¹ , Neus Latorre-Margalef¹² , Gergő Túri¹³ , Mihaela Lazăr¹⁴ , Clara Mazagatos^3,4 , Aitziber Echeverria¹⁰ , Stephen Abela¹⁵ , Marc Bourgeois¹⁶ , Ausenda Machado⁹ , Ralf Dürrwald¹⁷ , Goranka Petrović¹¹ , Beatrix Oroszi¹³ , Ligita Jancoriene¹⁸ , Alexandru Marin¹⁹ , Petr Husa²⁰ , Roisin Duffy⁷ , Frederika Dijkstra⁸ , Virtudes Gallardo García²¹ , Luise Goerlitz⁵ , Vincent Enouf²² , Charlene Bennett²³ , Mariëtte Hooiveld²⁴ , Raquel Guiomar²⁵ , Camino Trobajo-Sanmartín¹⁰ , Vesna Višekruna Vučina¹¹ , Tove Samuelsson Hagey¹² , Ana Sofía Lameiras Azevedo²⁶ , Jesús Castilla¹⁰ , Gerd Xuereb^15,27 , Bénédicte Delaere¹⁶ , Verónica Gómez⁹ , Kristin Tolksdorf⁵ , Sabrina Bacci²⁸ , Nathalie Nicolay²⁸ , Marlena Kaczmarek²⁸ , Angela MC Rose¹ , on behalf of the European IVE group²⁹
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Affiliations: ¹ Epiconcept, Paris, France ² National Centre for Microbiology, National Influenza Reference Laboratory, WHO-National Influenza Centre, Institute of Health Carlos III, Madrid, Spain ³ CIBER de Epidemiología y Salud Pública (CIBERESP), Institute of Health Carlos III, Madrid, Spain ⁴ National Centre for Epidemiology, Institute of Health Carlos III, Madrid, Spain ⁵ Department for Infectious Disease Epidemiology, Respiratory Infections Unit, Robert Koch Institute, Berlin, Germany ⁶ Sorbonne Université, INSERM, Institut Pierre Louis d'épidémiologie et de Santé Publique (IPLESP UMRS 1136), Paris, France ⁷ HSE Health Protection Surveillance Centre, Dublin, Ireland ⁸ National Institute for Public Health and the Environment, Centre for Infectious Diseases Control, Bilthoven, the Netherlands ⁹ Epidemiology Department, Instituto Nacional de Saúde Doutor Ricardo Jorge, Lisbon, Portugal ¹⁰ Instituto de Salud Pública de Navarra – IdiSNA – CIBERESP, Pamplona, Spain ¹¹ Croatian Institute of Public Health, Zagreb, Croatia ¹² Public Health Agency of Sweden, Stockholm, Sweden ¹³ National Laboratory for Health Security, Epidemiology and Surveillance Centre, Semmelweis University, Budapest, Hungary ¹⁴ Cantacuzino National Military Medical Institute for Research and Development, Bucharest, Romania ¹⁵ Infectious Disease Prevention and Control Unit (IDCU), Health Promotion and Disease Prevention, Msida, Malta ¹⁶ Department of Infectious Diseases, CHU UCL Namur (site Godinne), Université catholique de Louvain, Yvoir, Belgium ¹⁷ National Reference Centre for Influenza, Robert Koch Institute, Berlin, Germany ¹⁸ Clinic of Infectious Diseases and Dermatovenerology, Institute of Clinical Medicine, Medical Faculty, Vilnius University, Vilnius, Lithuania ¹⁹ Dr Victor Babes Clinical Hospital of Infectious and Tropical Diseases, Bucharest, Romania ²⁰ University Hospital Brno and Masaryk University, Brno, Czechia ²¹ Servicio de Vigilancia y Salud Laboral, Dirección General de Salud Pública y Ordenación Farmacéutica, Consejería de Salud y Consumo, Andalucía, Spain ²² Centre National de Référence Virus des Infections Respiratoire (CNR VIR), Institut Pasteur Université Paris Cité, Paris, France ²³ National Virus Reference Laboratory, University College Dublin, Dublin, Ireland ²⁴ Nivel, Utrecht, the Netherlands ²⁵ Laboratório Nacional Referência Gripe e outros Vírus Respiratórios, Instituto Nacional de Saúde Doutor Ricardo Jorge, Lisbon, Portugal ²⁶ Servicio de vigilancia y control epidemiológico, Subdirección general de Epidemiología y Vigilancia de la Salud, Dirección General de Salud pública, Valencia, Spain ²⁷ Department of Child and Adolescent Health, Mater Dei Hospital, Msida, Malta ²⁸ European Centre for Disease Prevention and Control, Stockholm, Sweden ²⁹ The members of the European IVE group are listed under Acknowledgements.

* These authors contributed equally to this article and share first authorship.
Correspondence:
Esther Kissling
e.kissling epiconcept.fr
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Citation style for this article: Maurel Marine, Howard Jennifer, Kissling Esther, Pozo Francisco, Pérez-Gimeno Gloria, Buda Silke, Sève Noémie, McKenna Adele, Meijer Adam, Rodrigues Ana Paula, Martínez-Baz Iván, Mlinarić Ivan, Latorre-Margalef Neus, Túri Gergő, Lazăr Mihaela, Mazagatos Clara, Echeverria Aitziber, Abela Stephen, Bourgeois Marc, Machado Ausenda, Dürrwald Ralf, Petrović Goranka, Oroszi Beatrix, Jancoriene Ligita, Marin Alexandru, Husa Petr, Duffy Roisin, Dijkstra Frederika, Gallardo García Virtudes, Goerlitz Luise, Enouf Vincent, Bennett Charlene, Hooiveld Mariëtte, Guiomar Raquel, Trobajo-Sanmartín Camino, Višekruna Vučina Vesna, Samuelsson Hagey Tove, Lameiras Azevedo Ana Sofía, Castilla Jesús, Xuereb Gerd, Delaere Bénédicte, Gómez Verónica, Tolksdorf Kristin, Bacci Sabrina, Nicolay Nathalie, Kaczmarek Marlena, Rose Angela MC, on behalf of the European IVE group. Interim 2023/24 influenza A vaccine effectiveness: VEBIS European primary care and hospital multicentre studies, September 2023 to January 2024. Euro Surveill. 2024;29(8):pii=2400089. https://doi.org/10.2807/1560-7917.ES.2024.29.8.2400089 Received: 12 Feb 2024; Accepted: 21 Feb 2024

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Abstract

Influenza A viruses circulated in Europe from September 2023 to January 2024, with influenza A(H1N1)pdm09 predominance. We provide interim 2023/24 influenza vaccine effectiveness (IVE) estimates from two European studies, covering 10 countries across primary care (EU-PC) and hospital (EU-H) settings. Interim IVE was higher against A(H1N1)pdm09 than A(H3N2): EU-PC influenza A(H1N1)pdm09 IVE was 53% (95% CI: 41 to 63) and 30% (95% CI: −3 to 54) against influenza A(H3N2). For EU-H, these were 44% (95% CI: 30 to 55) and 14% (95% CI: −32 to 43), respectively.

This work is licensed under a Creative Commons Attribution 4.0 International License.

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References

European Centre for Disease Prevention and Control (ECDC). European Respiratory Virus Surveillance Summary (ERVISS), 2024, Week 05. Stockholm: ECDC. [Accessed: 16 Feb 2024]. Available from: https://erviss.org
World Health Organization (WHO). Recommended composition of influenza virus vaccines for use in the 2023-2024 northern hemisphere influenza season. Geneva: WHO; 2023. Available from: https://www.who.int/publications/m/item/recommended-composition-of-influenza-virus-vaccines-for-use-in-the-2023-2024-northern-hemisphere-influenza-season
European Centre for Disease Prevention and Control (ECDC). Vaccine Scheduler. Stockholm: ECDC. [Accessed: 31 Jan 2024]. Available from: https://vaccine-schedule.ecdc.europa.eu/Scheduler/ByDisease?SelectedDiseaseId=15&SelectedCountryIdByDisease=-1
European Centre for Disease Prevention and Control (ECDC). Core protocol for ECDC studies of vaccine effectiveness against symptomatic laboratory-confirmed influenza or SARS-CoV-2 infection at primary care level: version 1.0, September 2023. Stockholm: ECDC; 2023. Available from: https://data.europa.eu/doi/10.2900/25966
European Centre for Disease Prevention and Control (ECDC). Core protocol for ECDC VEBIS studies of COVID-19 vaccine effectiveness against hospitalisation with Severe Acute Respiratory Infection laboratory-confirmed with SARS-CoV-2 or seasonal influenza - Version 2.0. Stockholm: ECDC; 2023. Available from: https://www.ecdc.europa.eu/sites/default/files/documents/covid-19-vaccine-effectiveness-sari-protocol-version-2.pdf
Covenay J. FIRTHLOGIT: Stata module to calculate bias reduction in logistic regression. Boston: Boston College Department of Economics; 2015. Available from: https://EconPapers.repec.org/RePEc:boc:bocode:s456948
European Centre for Disease Prevention and Control (ECDC). Influenza virus characterisation, Summary Europe, December 2023. Stockholm: ECDC; 2024. Available from: https://www.ecdc.europa.eu/sites/default/files/documents/influenza-ECDC-WHO-Report-december-2023.pdf
European Centre for Disease Prevention and Control (ECDC). Influenza virus characterisation, Summary Europe, August 2023. Stockholm: ECDC; 2023. Available from: https://www.ecdc.europa.eu/sites/default/files/documents/Influenza-characterization-August-2023.pdf
World Health Organization (WHO). Recommended composition of influenza virus vaccines for use in the 2022-2023 northern hemisphere influenza season. Geneva: WHO. [Accessed: 3 Feb 2023]. Available from: https://www.who.int/publications/m/item/recommended-composition-of-influenza-virus-vaccines-for-use-in-the-2022-2023-northern-hemisphere-influenza-season
Skowronski DM, Zhan Y, Kaweski SE, Sabaiduc S, Khalid A, Olsha R, et al. 2023/24 mid-season influenza and Omicron XBB.1.5 vaccine effectiveness estimates from the Canadian Sentinel Practitioner Surveillance Network (SPSN). Euro Surveill. 2024;29(7):2400076. https://doi.org/10.2807/1560-7917.ES.2024.29.7.2400076 PMID: 38362622
Maurel M, Pozo F, Pérez-Gimeno G, Buda S, Sève N, Oroszi B, et al. Influenza vaccine effectiveness in Europe: Results from the 2022-2023 VEBIS (Vaccine Effectiveness, Burden and Impact Studies) primary care multicentre study. Influenza Other Respir Viruses. 2024;18(1):e13243. https://doi.org/10.1111/irv.13243 PMID: 38204584
Rose A, Pozo F, Martínez-Baz I, Mazagatos C, Bossuyt N, Cauchi JP, et al. Vaccine effectiveness against influenza hospitalisation in adults during the 2022/23 mixed season of influenza A(H1N1)pdm09, A(H3N2) and B circulation, Europe: VEBIS SARI VE hospital network. Influenza Other Respir Viruses. 2024;18(2). https://doi.org/10.1111/irv.13255
Smolarchuk C, Ickert C, Zelyas N, Kwong JC, Buchan SA. Early influenza vaccine effectiveness estimates using routinely collected data, Alberta, Canada, 2023/24 season. Euro Surveill. 2024;29(2):2300709. https://doi.org/10.2807/1560-7917.ES.2024.29.2.2300709 PMID: 38214082

Interim 2023/24 influenza A vaccine effectiveness: VEBIS European primary care and hospital multicentre studies, September 2023 to January 2024

Citation style for this article: <a href="/search?value1=Marine+Maurel&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Maurel Marine</a>, <a href="/search?value1=Jennifer+Howard&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Howard Jennifer</a>, <a href="/search?value1=Esther+Kissling&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kissling Esther</a>, <a href="/search?value1=Francisco+Pozo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pozo Francisco</a>, <a href="/search?value1=Gloria+P%C3%A9rez-Gimeno&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pérez-Gimeno Gloria</a>, <a href="/search?value1=Silke+Buda&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Buda Silke</a>, <a href="/search?value1=No%C3%A9mie+S%C3%A8ve&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sève Noémie</a>, <a href="/search?value1=Adele+McKenna&option1=author&noRedirect=true" class="nonDisambigAuthorLink">McKenna Adele</a>, <a href="/search?value1=Adam+Meijer&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Meijer Adam</a>, <a href="/search?value1=Ana+Paula+Rodrigues&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rodrigues Ana Paula</a>, <a href="/search?value1=Iv%C3%A1n+Mart%C3%ADnez-Baz&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Martínez-Baz Iván</a>, <a href="/search?value1=Ivan+Mlinari%C4%87&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mlinarić Ivan</a>, <a href="/search?value1=Neus+Latorre-Margalef&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Latorre-Margalef Neus</a>, <a href="/search?value1=Gerg%C5%91+T%C3%BAri&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Túri Gergő</a>, <a href="/search?value1=Mihaela+Laz%C4%83r&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lazăr Mihaela</a>, <a href="/search?value1=Clara+Mazagatos&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mazagatos Clara</a>, <a href="/search?value1=Aitziber+Echeverria&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Echeverria Aitziber</a>, <a href="/search?value1=Stephen+Abela&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Abela Stephen</a>, <a href="/search?value1=Marc+Bourgeois&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bourgeois Marc</a>, <a href="/search?value1=Ausenda+Machado&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Machado Ausenda</a>, <a href="/search?value1=Ralf+D%C3%BCrrwald&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Dürrwald Ralf</a>, <a href="/search?value1=Goranka+Petrovi%C4%87&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Petrović Goranka</a>, <a href="/search?value1=Beatrix+Oroszi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Oroszi Beatrix</a>, <a href="/search?value1=Ligita+Jancoriene&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Jancoriene Ligita</a>, <a href="/search?value1=Alexandru+Marin&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Marin Alexandru</a>, <a href="/search?value1=Petr+Husa&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Husa Petr</a>, <a href="/search?value1=Roisin+Duffy&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Duffy Roisin</a>, <a href="/search?value1=Frederika+Dijkstra&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Dijkstra Frederika</a>, <a href="/search?value1=Virtudes+Gallardo+Garc%C3%ADa&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gallardo García Virtudes</a>, <a href="/search?value1=Luise+Goerlitz&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Goerlitz Luise</a>, <a href="/search?value1=Vincent+Enouf&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Enouf Vincent</a>, <a href="/search?value1=Charlene+Bennett&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bennett Charlene</a>, <a href="/search?value1=Mari%C3%ABtte+Hooiveld&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hooiveld Mariëtte</a>, <a href="/search?value1=Raquel+Guiomar&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Guiomar Raquel</a>, <a href="/search?value1=Camino+Trobajo-Sanmart%C3%ADn&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Trobajo-Sanmartín Camino</a>, <a href="/search?value1=Vesna+Vi%C5%A1ekruna+Vu%C4%8Dina&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Višekruna Vučina Vesna</a>, <a href="/search?value1=Tove+Samuelsson+Hagey&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Samuelsson Hagey Tove</a>, <a href="/search?value1=Ana+Sof%C3%ADa+Lameiras+Azevedo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lameiras Azevedo Ana Sofía</a>, <a href="/search?value1=Jes%C3%BAs+Castilla&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Castilla Jesús</a>, <a href="/search?value1=Gerd+Xuereb&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Xuereb Gerd</a>, <a href="/search?value1=B%C3%A9n%C3%A9dicte+Delaere&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Delaere Bénédicte</a>, <a href="/search?value1=Ver%C3%B3nica+G%C3%B3mez&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gómez Verónica</a>, <a href="/search?value1=Kristin+Tolksdorf&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Tolksdorf Kristin</a>, <a href="/search?value1=Sabrina+Bacci&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bacci Sabrina</a>, <a href="/search?value1=Nathalie+Nicolay&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nicolay Nathalie</a>, <a href="/search?value1=Marlena+Kaczmarek&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kaczmarek Marlena</a>, <a href="/search?value1=Angela+MC+Rose&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rose Angela MC</a>, <a href="/search?value1=on+behalf+of+the+European+IVE+group&option1=author&noRedirect=true" class="nonDisambigAuthorLink">on behalf of the European IVE group</a>. Interim 2023/24 influenza A vaccine effectiveness: VEBIS European primary care and hospital multicentre studies, September 2023 to January 2024. <a href="/content/ecdc">Euro Surveill.</a> 2024;29(8):pii=2400089. <a href="https://doi.org/10.2807/1560-7917.ES.2024.29.8.2400089" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2024.29.8.2400089</a> Received: 12 Feb 2024;   Accepted: 21 Feb 2024

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Interim 2023/24 influenza A vaccine effectiveness: VEBIS European primary care and hospital multicentre studies, September 2023 to January 2024

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