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Abstract

COVID-19 vaccination recommendations include healthcare workers (HCWs). We measured COVID-19 vaccine effectiveness (CVE) of the autumn 2023 dose against laboratory-confirmed SARS-CoV-2 infection in a prospective cohort study of 1,305 HCWs from 13 European hospitals. Overall CVE was 22% (95% CI: −17 to 48), 49% (95% CI: −8 to 76) before and −11% (95% CI: −84 to 34) after the start of BA.2.86/JN.1 predominant circulation. Autumn 2023 COVID-19 vaccination led to a moderate-to-low reduction in SARS-CoV-2 infection incidence in HCWs. Monitoring of CVE is crucial for COVID-19 prevention.

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/content/10.2807/1560-7917.ES.2024.29.44.2400680
2024-10-31
2024-11-01
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2024.29.44.2400680
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Effectiveness of the autumn 2023 COVID-19 vaccine dose in hospital-based healthcare workers: results of the VEBIS healthcare worker vaccine effectiveness cohort study, seven European countries, season 2023/24
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Camelia+Savulescu&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Savulescu Camelia</a>, <a href="/search?value1=Albert+Prats-Uribe&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Prats-Uribe Albert</a>, <a href="/search?value1=Kim+Brolin&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Brolin Kim</a>, <a href="/search?value1=Anneli+Uusk%C3%BCla&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Uusküla Anneli</a>, <a href="/search?value1=Colm+Bergin&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bergin Colm</a>, <a href="/search?value1=Catherine+Fleming&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Fleming Catherine</a>, <a href="/search?value1=Rita+Murri&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Murri Rita</a>, <a href="/search?value1=Viesturs+Zvirbulis&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Zvirbulis Viesturs</a>, <a href="/search?value1=Dace+Zavadska&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Zavadska Dace</a>, <a href="/search?value1=Vania+Gaio&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gaio Vania</a>, <a href="/search?value1=Corneliu+P+Popescu&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Popescu Corneliu P</a>, <a href="/search?value1=Raluca+Hrisca&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hrisca Raluca</a>, <a href="/search?value1=Maria+Cisneros&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cisneros Maria</a>, <a href="/search?value1=Miriam+Latorre-Mill%C3%A1n&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Latorre-Millán Miriam</a>, <a href="/search?value1=Liis+Lohur&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lohur Liis</a>, <a href="/search?value1=Jonathan+McGrath&option1=author&noRedirect=true" class="nonDisambigAuthorLink">McGrath Jonathan</a>, <a href="/search?value1=Lauren+Ferguson&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ferguson Lauren</a>, <a href="/search?value1=Katleen+De+Gaetano+Donati&option1=author&noRedirect=true" class="nonDisambigAuthorLink">De Gaetano Donati Katleen</a>, <a href="/search?value1=Ilze+Abolina&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Abolina Ilze</a>, <a href="/search?value1=Dagne+Gravele&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gravele Dagne</a>, <a href="/search?value1=Ausenda+Machado&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Machado Ausenda</a>, <a href="/search?value1=Simin-Aysel+Florescu&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Florescu Simin-Aysel</a>, <a href="/search?value1=Mihaela+Lazar&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lazar Mihaela</a>, <a href="/search?value1=Pilar+Subirats&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Subirats Pilar</a>, <a href="/search?value1=Laura+Clusa+Cuesta&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Clusa Cuesta Laura</a>, <a href="/search?value1=Jacklyn+Sui&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sui Jacklyn</a>, <a href="/search?value1=Claire+Kenny&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kenny Claire</a>, <a href="/search?value1=Rosaria+Santangelo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Santangelo Rosaria</a>, <a href="/search?value1=Dainis+Krievins&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Krievins Dainis</a>, <a href="/search?value1=Elza+Anna+Barzdina&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Barzdina Elza Anna</a>, <a href="/search?value1=Camila+Valadas+Henriques&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Valadas Henriques Camila</a>, <a href="/search?value1=Alma+Gabriela+Kosa&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kosa Alma Gabriela</a>, <a href="/search?value1=Saftica-Mariana+Pohrib&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pohrib Saftica-Mariana</a>, <a href="/search?value1=Carmen+Mu%C3%B1oz-Almagro&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Muñoz-Almagro Carmen</a>, <a href="/search?value1=Ana+Milagro&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Milagro Ana</a>, <a href="/search?value1=Sabrina+Bacci&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bacci Sabrina</a>, <a href="/search?value1=Anthony+Nardone&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nardone Anthony</a>, <a href="/search?value1=VEBIS+HCW+VE+study+group&option1=author&noRedirect=true" class="nonDisambigAuthorLink">VEBIS HCW VE study group</a></span>. Effectiveness of the autumn 2023 COVID-19 vaccine dose in hospital-based healthcare workers: results of the VEBIS healthcare worker vaccine effectiveness cohort study, seven European countries, season 2023/24. <a href="/content/ecdc">Euro Surveill.</a> 2024;29(44):pii=2400680. <a href="https://doi.org/10.2807/1560-7917.ES.2024.29.44.2400680" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2024.29.44.2400680</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 14 Oct 2024;&nbsp;&nbsp; <span class="generated">Accepted</span>: 31 Oct 2024 </span> </p>
/content/10.2807/1560-7917.ES.2024.29.44.2400680
/content/10.2807/1560-7917.ES.2024.29.44.2400680
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