1887
  1. Home
  2. Eurosurveillance
  3. Volume 29, Issue 31, 01/Aug/2024
  4. Article
Rapid communication Open Access
Like 0
Download

Abstract

As other European countries, France is experiencing a resurgence of pertussis in 2024. Between 1 January and 31 May 2024, 5,616 (24.9%) positive qPCR tests were identified, following a 3-year period of almost null incidence. Of 67 cultured and whole genome sequenced isolates, 66 produced pertactin and 56 produced FIM2, in contrast to pre-COVID-19 years. One isolate of genotype Bp-AgST4 was resistant to macrolides. Pertussis resurgence may favour isolates that produce FIM2 and pertactin.

© Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Loading

Article metrics loading...

/content/10.2807/1560-7917.ES.2024.29.31.2400459
2024-08-01
2024-09-08
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2024.29.31.2400459
Loading
Loading full text...

Full text loading...

/deliver/fulltext/eurosurveillance/29/31/eurosurv-29-31-1.html?itemId=/content/10.2807/1560-7917.ES.2024.29.31.2400459&mimeType=html&fmt=ahah

References

  1. Machado MB, Passos SD. Severe pertussis in childhood: update and controversy - systematic review. Rev Paul Pediatr. 2019;37(3):351-62.  https://doi.org/10.1590/1984-0462/;2019;37;3;00006  PMID: 31116241 
  2. Matczak S, Levy C, Fortas C, Cohen JF, Béchet S, Aït El Belghiti F, et al. Association between the COVID-19 pandemic and pertussis derived from multiple nationwide data sources, France, 2013 to 2020. Euro Surveill. 2022;27(25):2100933.  https://doi.org/10.2807/1560-7917.ES.2022.27.25.2100933  PMID: 35748301 
  3. Tubiana S, Belchior E, Guillot S, Guiso N, Lévy-Bruhl D, Renacoq Participants. Monitoring the impact of vaccination on pertussis in infants using an active hospital-based pediatric surveillance network: results from 17 years’ experience, 1996-2012, France. Pediatr Infect Dis J. 2015;34(8):814-20.  https://doi.org/10.1097/INF.0000000000000739  PMID: 25955837 
  4. Bouchez V, Guillot S, Landier A, Armatys N, Matczak S, Toubiana J, et al. Evolution of Bordetella pertussis over a 23-year period in France, 1996 to 2018. Euro Surveill. 2021;26(37):2001213.  https://doi.org/10.2807/1560-7917.ES.2021.26.37.2001213  PMID: 34533118 
  5. Bouchez V, Brun D, Cantinelli T, Dore G, Njamkepo E, Guiso N. First report and detailed characterization of B. pertussis isolates not expressing pertussis toxin or pertactin. Vaccine. 2009;27(43):6034-41.  https://doi.org/10.1016/j.vaccine.2009.07.074  PMID: 19666155 
  6. Guillot S, Descours G, Gillet Y, Etienne J, Floret D, Guiso N. Macrolide-resistant Bordetella pertussis infection in newborn girl, France. Emerg Infect Dis. 2012;18(6):966-8.  https://doi.org/10.3201/eid1806.120091  PMID: 22608348 
  7. Bouchez V, Guglielmini J, Dazas M, Landier A, Toubiana J, Guillot S, et al. Genomic sequencing of Bordetella pertussis for epidemiology and global surveillance of whooping cough. Emerg Infect Dis. 2018;24(6):988-94.  https://doi.org/10.3201/eid2406.171464  PMID: 29774847 
  8. Bridel S, Bouchez V, Brancotte B, Hauck S, Armatys N, Landier A, et al. A comprehensive resource for Bordetella genomic epidemiology and biodiversity studies. Nat Commun. 2022;13(1):3807.  https://doi.org/10.1038/s41467-022-31517-8  PMID: 35778384 
  9. Domenech de Cellès M, Magpantay FMG, King AA, Rohani P. The pertussis enigma: reconciling epidemiology, immunology and evolution. Proc Biol Sci. 2016;283(1822):283.  https://doi.org/10.1098/rspb.2015.2309  PMID: 26763701 
  10. Tessier E, Campbell H, Ribeiro S, Rai Y, Burton S, Roy P, et al. Impact of the COVID-19 pandemic on Bordetella pertussis infections in England. BMC Public Health. 2022;22(1):405.  https://doi.org/10.1186/s12889-022-12830-9  PMID: 35220973 
  11. Bouchez V, Toubiana J, Guillot S, Parapertussis Study Group, El Belghiti FA, Landier A, et al. . Transient reemergence of Bordetella parapertussis in France in 2022. J Med Microbiol. 2024;73(7): (Forthcoming).  https://doi.org/10.1099/jmm.0.001843  PMID: 38995835 
  12. Feinmann J. Analysis reveals global post-covid surge in infectious diseases. BMJ. 2024;385:q1348.  https://doi.org/10.1136/bmj.q1348  PMID: 38889948 
  13. Ma L, Caulfield A, Dewan KK, Harvill ET. Pertactin-deficient Bordetella pertussis, vaccine-driven evolution, and reemergence of pertussis. Emerg Infect Dis. 2021;27(6):1561-6.  https://doi.org/10.3201/eid2706.203850  PMID: 34014152 
  14. Barkoff AM, Mertsola J, Pierard D, Dalby T, Hoegh SV, Guillot S, et al. Pertactin-deficient Bordetella pertussis isolates: evidence of increased circulation in Europe, 1998 to 2015. Euro Surveill. 2019;24(7):1700832.  https://doi.org/10.2807/1560-7917.ES.2019.24.7.1700832  PMID: 30782265 
  15. Gorringe AR, Vaughan TE. Bordetella pertussis fimbriae (Fim): relevance for vaccines. Expert Rev Vaccines. 2014;13(10):1205-14.  https://doi.org/10.1586/14760584.2014.930667  PMID: 25102891 
  16. Matczak S, Bouchez V, Leroux P, Douché T, Collinet N, Landier A, et al. Biological differences between FIM2 and FIM3 fimbriae of Bordetella pertussis: not just the serotype. Microbes Infect. 2023;25(7):105152.  https://doi.org/10.1016/j.micinf.2023.105152  PMID: 37245862 
  17. Bart MJ, Harris SR, Advani A, Arakawa Y, Bottero D, Bouchez V, et al. Global population structure and evolution of Bordetella pertussis and their relationship with vaccination. MBio. 2014;5(2):e01074.  https://doi.org/10.1128/mBio.01074-14  PMID: 24757216 
  18. Lefrancq N, Bouchez V, Fernandes N, Barkoff AM, Bosch T, Dalby T, et al. Global spatial dynamics and vaccine-induced fitness changes of Bordetella pertussis. Sci Transl Med. 2022;14(642):eabn3253.  https://doi.org/10.1126/scitranslmed.abn3253  PMID: 35476597 
  19. Ivaska L, Barkoff AM, Mertsola J, He Q. Macrolide resistance in Bordetella pertussis: current situation and future challenges. Antibiotics (Basel). 2022;11(11):1570.  https://doi.org/10.3390/antibiotics11111570  PMID: 36358225 
  20. Pfister P, Corti N, Hobbie S, Bruell C, Zarivach R, Yonath A, et al. 23S rRNA base pair 2057-2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A-->G. Proc Natl Acad Sci USA. 2005;102(14):5180-5.  https://doi.org/10.1073/pnas.0501598102  PMID: 15795375 
Resurgence of Bordetella pertussis, including one macrolide-resistant isolate, France, 2024
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Carla+Rodrigues&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rodrigues Carla</a>, <a href="/search?value1=Val%C3%A9rie+Bouchez&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bouchez Valérie</a>, <a href="/search?value1=Ana%C3%AFs+Soares&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Soares Anaïs</a>, <a href="/search?value1=Sabine+Trombert-Paolantoni&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Trombert-Paolantoni Sabine</a>, <a href="/search?value1=Fatima+A%C3%AFt+El+Belghiti&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Aït El Belghiti Fatima</a>, <a href="/search?value1=J%C3%A9r%C3%A9mie+F+Cohen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cohen Jérémie F</a>, <a href="/search?value1=Nathalie+Armatys&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Armatys Nathalie</a>, <a href="/search?value1=Annie+Landier&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Landier Annie</a>, <a href="/search?value1=Thomas+Blanchot&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Blanchot Thomas</a>, <a href="/search?value1=Marie+Hervo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hervo Marie</a>, <a href="/search?value1=REMICOQ+study+group&option1=author&noRedirect=true" class="nonDisambigAuthorLink">REMICOQ study group</a>, <a href="/search?value1=Julie+Toubiana&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Toubiana Julie</a>, <a href="/search?value1=Sylvain+Brisse&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Brisse Sylvain</a></span>. Resurgence of Bordetella pertussis, including one macrolide-resistant isolate, France, 2024. <a href="/content/ecdc">Euro Surveill.</a> 2024;29(31):pii=2400459. <a href="https://doi.org/10.2807/1560-7917.ES.2024.29.31.2400459" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2024.29.31.2400459</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 15 Jul 2024;&nbsp;&nbsp; <span class="generated">Accepted</span>: 31 Jul 2024 </span> </p>
/content/10.2807/1560-7917.ES.2024.29.31.2400459
/content/10.2807/1560-7917.ES.2024.29.31.2400459
Loading

Data & Media loading...

Supplementary data

Submit comment
Close
Comment moderation successfully completed
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error