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Abstract

Background

is a leading cause of moderate-to-severe diarrhoea worldwide and diarrhoeal deaths in children in low- and-middle-income countries.

Aim

We investigated trends and characteristics of shigellosis and antimicrobial resistance of in Israel.

Methods

We analysed data generated by the Sentinel Laboratory-Based Surveillance Network for Enteric Pathogens that systematically collects data on detection of at sentinel laboratories, along with the characterisation of the isolates at the National Reference Laboratory. Trends in the shigellosis incidence were assessed using Joinpoint regression and interrupted time-series analyses.

Results

The average incidence of culture-confirmed shigellosis in Israel declined from 114 per 100,000 population (95% confidence interval (CI): 112–115) 1998–2004 to 80 per 100,000 population (95% CI: 79–82) 2005–2011. This rate remained stable 2012–2019, being 18–32 times higher than that reported from the United States or European high-income countries. After decreasing to its lowest values during the COVID-19 pandemic years (19/100,000 in 2020 and 5/100,000 in 2021), the incidence of culture-confirmed shigellosis increased to 39 per 100,000 population in 2022. is the most common serogroup, responsible for a cyclic occurrence of propagated epidemics, and the proportion of has decreased. Simultaneous resistance of to ceftriaxone, ampicillin and sulphamethoxazole-trimethoprim increased from 8.5% (34/402) in 2020 to 92.0% (801/876) in 2022.

Conclusions

These findings reinforce the need for continuous laboratory-based surveillance and inform the primary and secondary prevention strategies for shigellosis in Israel and other endemic high-income countries or communities.

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This work is licensed under a Creative Commons Attribution 4.0 International License.
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2024-08-01
2024-11-19
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2024.29.31.2400022
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Twenty-five years of sentinel laboratory-based surveillance of shigellosis in a high-income country endemic for the disease, Israel, 1998 to 2022
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Dani+Cohen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cohen Dani</a>, <a href="/search?value1=Orit+Treygerman&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Treygerman Orit</a>, <a href="/search?value1=Shifra+Ken-Dror&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ken-Dror Shifra</a>, <a href="/search?value1=Orli+Sagi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sagi Orli</a>, <a href="/search?value1=Merav+Strauss&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Strauss Merav</a>, <a href="/search?value1=Miriam+Parizade&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Parizade Miriam</a>, <a href="/search?value1=Sophy+Goren&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Goren Sophy</a>, <a href="/search?value1=Anal%C3%ADa+V+Ezernitchi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ezernitchi Analía V</a>, <a href="/search?value1=Assaf+Rokney&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rokney Assaf</a>, <a href="/search?value1=Lital+Keinan-Boker&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Keinan-Boker Lital</a>, <a href="/search?value1=Ravit+Bassal&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bassal Ravit</a></span>. Twenty-five years of sentinel laboratory-based surveillance of shigellosis in a high-income country endemic for the disease, Israel, 1998 to 2022. <a href="/content/ecdc">Euro Surveill.</a> 2024;29(31):pii=2400022. <a href="https://doi.org/10.2807/1560-7917.ES.2024.29.31.2400022" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2024.29.31.2400022</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 03 Jan 2024;&nbsp;&nbsp; <span class="generated">Accepted</span>: 16 May 2024 </span> </p>
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