1887
Rapid communication Open Access
Like 0

Abstract

We report an epidemic of parvovirus B19 infections in Denmark during the first quarter of 2024, with a peak incidence 3.5 times higher than during the most recent epidemic in 2017. In total, 20.1% (130/648) of laboratory-confirmed cases were pregnant. Severe adverse outcomes were observed among 12.3% (16/130) of pregnant people and included foetal anaemia, foetal hydrops and miscarriage. Parvovirus B19 infection is not systematically monitored, but a national laboratory-based surveillance system is currently being established in Denmark.

Loading

Article metrics loading...

/content/10.2807/1560-7917.ES.2024.29.24.2400299
2024-06-13
2024-06-30
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2024.29.24.2400299
Loading
Loading full text...

Full text loading...

/deliver/fulltext/eurosurveillance/29/24/eurosurv-29-24_2.html?itemId=/content/10.2807/1560-7917.ES.2024.29.24.2400299&mimeType=html&fmt=ahah

References

  1. Tolfvenstam T, Papadogiannakis N, Norbeck O, Petersson K, Broliden K. Frequency of human parvovirus B19 infection in intrauterine fetal death. Lancet. 2001;357(9267):1494-7.  https://doi.org/10.1016/S0140-6736(00)04647-X  PMID: 11377602 
  2. Mossong J, Hens N, Friederichs V, Davidkin I, Broman M, Litwinska B, et al. Parvovirus B19 infection in five European countries: seroepidemiology, force of infection and maternal risk of infection. Epidemiol Infect. 2008;136(8):1059-68.  https://doi.org/10.1017/S0950268807009661  PMID: 17956642 
  3. Valeur-Jensen AK, Pedersen CB, Westergaard T, Jensen IP, Lebech M, Andersen PK, et al. Risk factors for parvovirus B19 infection in pregnancy. JAMA. 1999;281(12):1099-105.  https://doi.org/10.1001/jama.281.12.1099  PMID: 10188660 
  4. Statens Serum Institut (SSI). Parvovirus B19 and pregnancy. Epi-News, no. 13 2024. Copenhagen: SSI; 10 Apr 2024. Available from: https://en.ssi.dk/news/epi-news/2024/no-13---2024
  5. Chisaka H, Morita E, Yaegashi N, Sugamura K. Parvovirus B19 and the pathogenesis of anaemia. Rev Med Virol. 2003;13(6):347-59.  https://doi.org/10.1002/rmv.395  PMID: 14625883 
  6. Enders M, Klingel K, Weidner A, Baisch C, Kandolf R, Schalasta G, et al. Risk of fetal hydrops and non-hydropic late intrauterine fetal death after gestational parvovirus B19 infection. J Clin Virol. 2010;49(3):163-8.  https://doi.org/10.1016/j.jcv.2010.07.014  PMID: 20729141 
  7. Puccetti C, Contoli M, Bonvicini F, Cervi F, Simonazzi G, Gallinella G, et al. Parvovirus B19 in pregnancy: possible consequences of vertical transmission. Prenat Diagn. 2012;32(9):897-902.  https://doi.org/10.1002/pd.3930  PMID: 22777688 
  8. Enders M, Weidner A, Zoellner I, Searle K, Enders G. Fetal morbidity and mortality after acute human parvovirus B19 infection in pregnancy: prospective evaluation of 1018 cases. Prenat Diagn. 2004;24(7):513-8.  https://doi.org/10.1002/pd.940  PMID: 15300741 
  9. Lamont RF, Sobel JD, Vaisbuch E, Kusanovic JP, Mazaki-Tovi S, Kim SK, et al. Parvovirus B19 infection in human pregnancy. BJOG. 2011;118(2):175-86.  https://doi.org/10.1111/j.1471-0528.2010.02749.x  PMID: 21040396 
  10. Kosian P, Hellmund A, Geipel A, Bald R, Geist OM, Böckenhoff P, et al. Intrauterine transfusion in 103 fetuses with severe anemia caused by parvovirus infection. A multicenter retrospective study. Arch Gynecol Obstet. 2023;308(1):117-25.  https://doi.org/10.1007/s00404-022-06712-z  PMID: 35916962 
  11. Valeur-Jensen AK, Pedersen CB, Westergaard T, Jensen IP, Lebech M, Andersen PK, et al. Risk factors for parvovirus B19 infection in pregnancy. JAMA. 1999;281(12):1099-105.  https://doi.org/10.1001/jama.281.12.1099  PMID: 10188660 
  12. Young NS, Brown KE. Parvovirus B19. N Engl J Med. 2004;350(6):586-97.  https://doi.org/10.1056/NEJMra030840  PMID: 14762186 
  13. Sundhedsstyrelsen (SST). Anbefalinger for svangreomsorgen. [Recommendations for pregnancy care]. Copenhagen: SST; 2021. Danish. Available from: https://www.sst.dk/-/media/Udgivelser/2021/Anbefalinger-svangreomsorgen/Svangreomsorg-2022-ny.ashx
  14. Sundhedsstyrelsen (SST). Information til læger om parvovirus B19 og graviditet. [Information to physicians on parvovirus B19 and pregnancy]. Copenhagen: SST; 29 Apr 2024. Danish. Available from: https://www.sst.dk/-/media/Udgivelser/2024/Lussingesyge/Information-til-laeger-om-parvovirus-B19-lussingesyge-og-graviditet.ashx?sc_lang=da&hash=686E5C137BEA99B089B96954EB09B5F1
  15. Santé Publique France (SPF). Epidémie d’infections à Parvovirus B19 en France. Point au 22 avril 2024. [Epidemic of parvovirus B19 infections in France. Update as of 22 April 2024]. Saint-Maurice: SPF; 22 Apr 2024. French. Available from: https://www.santepubliquefrance.fr/docs/epidemie-d-infections-a-parvovirus-b19-en-france.-point-au-22-avril-2024
  16. European Centre for Disease Prevention and Control (ECDC). Communicable Disease Threats Report. Week 16, 14-20 April. Stockholm: ECDC; 2024. Available from: https://www.ecdc.europa.eu/sites/default/files/documents/communicable-disease-threats-report-week-16-2024_final.pdf
/content/10.2807/1560-7917.ES.2024.29.24.2400299
Loading

Data & Media loading...

Submit comment
Close
Comment moderation successfully completed
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error