1887
  1. Home
  2. Eurosurveillance
  3. Volume 29, Issue 24, 13/Jun/2024
  4. Article
Rapid communication Open Access
Like 0
Download

SDG 3: Antimicrobial resistance

Abstract

In 2003−2023, amid 5,436 isolates collected globally through the Multidrug-Resistant Organism Repository and Surveillance Network, 97 were ST19PAS, 34 of which carbapenem-resistant. Strains (n = 32) sampled after 2019 harboured either , , and/or . Phylogenetic analysis of the 97 isolates and 11 publicly available ST19 genomes revealed three sub-lineages of carbapenemase-producing isolates from mainly Ukraine and Georgia, including an epidemic clone carrying all three carbapenemase genes. Infection control and global surveillance of carbapenem-resistant remain important.

© Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Loading

Article metrics loading...

/content/10.2807/1560-7917.ES.2024.29.24.2400259
2024-06-13
2025-02-12
/content/10.2807/1560-7917.ES.2024.29.24.2400259
Loading
Loading full text...

Full text loading...

/deliver/fulltext/eurosurveillance/29/24/eurosurv-29-24_3.html?itemId=/content/10.2807/1560-7917.ES.2024.29.24.2400259&mimeType=html&fmt=ahah

References

  1. Lesho E, Craft D, Kirkup BC Jr, Waterman P, Summers A, Vahey MT, et al. Surveillance, characterisation, and preservation of multidrug-resistant bacteria. Lancet Infect Dis. 2011;11(1):8-10.  https://doi.org/10.1016/S1473-3099(10)70261-9  PMID: 21183141 
  2. Waterman P, Kwak Y, Clifford R, Julius M, Onmus-Leone F, Tsurgeon C, et al. A multidrug-resistance surveillance network: 1 year on. Lancet Infect Dis. 2012;12(8):587-8.  https://doi.org/10.1016/S1473-3099(12)70149-4  PMID: 22835896 
  3. Magiorakos AP, Srinivasan A, Carey RB, Carmeli Y, Falagas ME, Giske CG, et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect. 2012;18(3):268-81.  https://doi.org/10.1111/j.1469-0691.2011.03570.x  PMID: 21793988 
  4. Galac MR, Snesrud E, Lebreton F, Stam J, Julius M, Ong AC, et al. A diverse panel of clinical Acinetobacter baumannii for research and development. Antimicrob Agents Chemother. 2020;64(10):e00840-20.  https://doi.org/10.1128/AAC.00840-20  PMID: 32718956 
  5. Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Susceptibility Testing. 33rd ed. CLSI Supplement M100. CLSI; 2023. Available from: https://clsi.org/media/tc4b1paf/m10033_samplepages-1.pdf
  6. Hamed SM, Hussein AFA, Al-Agamy MH, Radwan HH, Zafer MM. Genetic configuration of genomic resistance islands in Acinetobacter baumannii clinical isolates from Egypt. Front Microbiol. 2022;13:878912.  https://doi.org/10.3389/fmicb.2022.878912  PMID: 35935207 
  7. Russo TA, Alvarado CL, Davies CJ, Drayer ZJ, Carlino-MacDonald U, Hutson A, et al. Differentiation of hypervirulent and classical Klebsiella pneumoniae with acquired drug resistance. MBio. 2024;15(2):e0286723.  https://doi.org/10.1128/mbio.02867-23  PMID: 38231533 
  8. Lam MMC, Koong J, Holt KE, Hall RM, Hamidian M. Detection and typing of plasmids in Acinetobacter baumannii using rep genes encoding replication initiation proteins. Microbiol Spectr. 2023;11(1):e0247822.  https://doi.org/10.1128/spectrum.02478-22  PMID: 36472426 
  9. Ross K, Varani AM, Snesrud E, Huang H, Alvarenga DO, Zhang J, et al. TnCentral: a Prokaryotic transposable element database and web portal for transposon analysis. MBio. 2021;12(5):e0206021.  https://doi.org/10.1128/mBio.02060-21  PMID: 34517763 
  10. Nigro S, Hall RM. Distribution of the blaOXA-23-containing transposons Tn2006 and Tn2008 in Australian carbapenem-resistant Acinetobacter baumannii isolates. J Antimicrob Chemother. 2015;70(8):2409-11.  https://doi.org/10.1093/jac/dkv102  PMID: 25881617 
  11. Hamidian M, Hall RM. AbaR4 replaces AbaR3 in a carbapenem-resistant Acinetobacter baumannii isolate belonging to global clone 1 from an Australian hospital. J Antimicrob Chemother. 2011;66(11):2484-91.  https://doi.org/10.1093/jac/dkr356  PMID: 21873287 
  12. Hamidian M, Nigro SJ. Emergence, molecular mechanisms and global spread of carbapenem-resistant Acinetobacter baumannii. Microb Genom. 2019;5(10):e000306.  https://doi.org/10.1099/mgen.0.000306  PMID: 31599224 
  13. European Centre for Disease Prevention and Control (ECDC). Antimicrobial resistance surveillance in Europe 2022-2020 data. Stockholm: ECDC; 2022. Available from: https://www.ecdc.europa.eu/en/publications-data/antimicrobial-resistance-surveillance-europe-2022-2020-data
  14. Tamma PD, Aitken SL, Bonomo RA, Mathers AJ, van Duin D, Clancy CJ. Infectious Diseases Society of America 2023 guidance on the treatment of antimicrobial resistant gram-negative infections. Clin Infect Dis. 2023;ciad428. Epub ahead of print.  https://doi.org/10.1093/cid/ciad428  PMID: 37463564 
  15. Poirel L, Nordmann P. Carbapenem resistance in Acinetobacter baumannii: mechanisms and epidemiology. Clin Microbiol Infect. 2006;12(9):826-36.  https://doi.org/10.1111/j.1469-0691.2006.01456.x  PMID: 16882287 
  16. Diancourt L, Passet V, Nemec A, Dijkshoorn L, Brisse S. The population structure of Acinetobacter baumannii: expanding multiresistant clones from an ancestral susceptible genetic pool. PLoS One. 2010;5(4):e10034.  https://doi.org/10.1371/journal.pone.0010034  PMID: 20383326 
  17. Zenati K, Touati A, Bakour S, Sahli F, Rolain JM. Characterization of NDM-1- and OXA-23-producing Acinetobacter baumannii isolates from inanimate surfaces in a hospital environment in Algeria. J Hosp Infect. 2016;92(1):19-26.  https://doi.org/10.1016/j.jhin.2015.09.020  PMID: 26615460 
  18. Lorenzin G, Scaltriti E, Gargiulo F, Caccuri F, Piccinelli G, Gurrieri F, et al. Extensively drug-resistant Acinetobacter baumannii isolated from intensive care units in northern Italy: a genomic approach to characterize new sequence types. Future Microbiol. 2019;14(15):1281-92.  https://doi.org/10.2217/fmb-2019-0083  PMID: 31638422 
  19. Fursova NK, Fursov MV, Astashkin EI, Fursova AD, Novikova TS, Kislichkina AA, et al. Multidrug-resistant and extensively drug-resistant Acinetobacter baumannii causing nosocomial meningitis in the neurological intensive care unit. Microorganisms. 2023;11(8):2020.  https://doi.org/10.3390/microorganisms11082020  PMID: 37630581 
  20. Farlow J, Nozadze M, Mitaishvili N, Kotorashvili A, Kotoria N, Arobelidze K, et al. Comparative genomic analysis of four multidrug-resistant isolates of Acinetobacter baumannii from Georgia. J Glob Antimicrob Resist. 2020;21:363-8.  https://doi.org/10.1016/j.jgar.2019.11.002  PMID: 31730823 
  21. Poirel L, Bonnin RA, Nordmann P. Genetic basis of antibiotic resistance in pathogenic Acinetobacter species. IUBMB Life. 2011;63(12):1061-7.  https://doi.org/10.1002/iub.532  PMID: 21990280 
  22. Kitti T, Manrueang S, Leungtongkam U, Khongfak S, Thummeepak R, Wannalerdsakun S, et al. Genomic relatedness and dissemination of blaNDM-5 among Acinetobacter baumannii isolated from hospital environments and clinical specimens in Thailand. PeerJ. 2023;11:e14831.  https://doi.org/10.7717/peerj.14831  PMID: 36778153 
  23. Luo TL, Harmer CJ, Lebreton F, Stam J, Bennett JW, Hall RM, et al. Identification of an outbreak cluster of extensively antibiotic-resistant GC1 Acinetobacter baumannii isolates in U.S. military treatment facilities. Microbiol Spectr. 2023;11(3):e0046223.  https://doi.org/10.1128/spectrum.00462-23  PMID: 37140387 
Detection of carbapenemase producing Acinetobacter baumannii ST19 from Georgia and Ukraine carrying blaOXA-23, blaOXA-72, and/or blaNDM-5, December 2019 to June 2023
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Ting+L+Luo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Luo Ting L</a>, <a href="/search?value1=Melissa+J+Martin&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Martin Melissa J</a>, <a href="/search?value1=Valentyn+Kovalchuk&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kovalchuk Valentyn</a>, <a href="/search?value1=Viacheslav+Kondratiuk&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kondratiuk Viacheslav</a>, <a href="/search?value1=Nino+Trapaidze&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Trapaidze Nino</a>, <a href="/search?value1=Magda+Metreveli&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Metreveli Magda</a>, <a href="/search?value1=Christine+E+Hulseberg&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hulseberg Christine E</a>, <a href="/search?value1=Henry+D+Dao&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Dao Henry D</a>, <a href="/search?value1=Yoon+I+Kwak&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kwak Yoon I</a>, <a href="/search?value1=Rosslyn+Maybank&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Maybank Rosslyn</a>, <a href="/search?value1=Thomas+A+Musich&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Musich Thomas A</a>, <a href="/search?value1=Matthew+R+Scherer&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Scherer Matthew R</a>, <a href="/search?value1=Jason+W+Bennett&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bennett Jason W</a>, <a href="/search?value1=Patrick+T+Mc+Gann&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mc Gann Patrick T</a>, <a href="/search?value1=Francois+Lebreton&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lebreton Francois</a></span>. Detection of carbapenemase producing Acinetobacter baumannii ST19 from Georgia and Ukraine carrying blaOXA-23, blaOXA-72, and/or blaNDM-5, December 2019 to June 2023. <a href="/content/ecdc">Euro Surveill.</a> 2024;29(24):pii=2400259. <a href="https://doi.org/10.2807/1560-7917.ES.2024.29.24.2400259" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2024.29.24.2400259</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 26 Apr 2024;&nbsp;&nbsp; <span class="generated">Accepted</span>: 12 Jun 2024 </span> </p>
/content/10.2807/1560-7917.ES.2024.29.24.2400259
/content/10.2807/1560-7917.ES.2024.29.24.2400259
Loading

Data & Media loading...

Supplementary data

Submit comment
Close
Comment moderation successfully completed
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error