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Abstract

In 2023, an increase of OXA-48-producing was noticed by the Lithuanian National Public Health Surveillance Laboratory. Whole genome sequencing (WGS) of 106 OXA-48-producing isolates revealed three distinct clusters of carbapenemase-producing high-risk clones, including sequence type (ST) 45 (n = 35 isolates), ST392 (n = 32) and ST395 (n = 28), involving six, six and nine hospitals in different regions, respectively. These results enabled targeted investigation and control, and underscore the value of national WGS-based surveillance for antimicrobial resistance.

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/content/10.2807/1560-7917.ES.2024.29.16.2400188
2024-04-18
2024-12-22
/content/10.2807/1560-7917.ES.2024.29.16.2400188
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Emergence of OXA-48-producing Klebsiella pneumoniae in Lithuania, 2023: a multi-cluster, multi-hospital outbreak
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Paulius+Grei%C4%8Dius&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Greičius Paulius</a>, <a href="/search?value1=Marius+Linkevicius&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Linkevicius Marius</a>, <a href="/search?value1=Jelena+Razmuk&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Razmuk Jelena</a>, <a href="/search?value1=Jekaterina+Sinotova&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sinotova Jekaterina</a>, <a href="/search?value1=Erik+Alm&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Alm Erik</a>, <a href="/search?value1=Olov+Svartstr%C3%B6m&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Svartström Olov</a>, <a href="/search?value1=Valeria+Bortolaia&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bortolaia Valeria</a>, <a href="/search?value1=Egl%C4%97+Kudirkien%C4%97&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kudirkienė Eglė</a>, <a href="/search?value1=Louise+Roer&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Roer Louise</a>, <a href="/search?value1=Rene+S+Hendriksen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hendriksen Rene S</a>, <a href="/search?value1=Gabija+Tamoli%C5%ABnait%C4%97&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Tamoliūnaitė Gabija</a>, <a href="/search?value1=Daniel+Palm&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Palm Daniel</a>, <a href="/search?value1=Dominique+L+Monnet&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Monnet Dominique L</a>, <a href="/search?value1=Anke+Kohlenberg&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kohlenberg Anke</a>, <a href="/search?value1=Algirdas+Gri%C5%A1kevi%C4%8Dius&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Griškevičius Algirdas</a></span>. Emergence of OXA-48-producing Klebsiella pneumoniae in Lithuania, 2023: a multi-cluster, multi-hospital outbreak. <a href="/content/ecdc">Euro Surveill.</a> 2024;29(16):pii=2400188. <a href="https://doi.org/10.2807/1560-7917.ES.2024.29.16.2400188" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2024.29.16.2400188</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 28 Mar 2024;&nbsp;&nbsp; <span class="generated">Accepted</span>: 17 Apr 2024 </span> </p>
/content/10.2807/1560-7917.ES.2024.29.16.2400188
/content/10.2807/1560-7917.ES.2024.29.16.2400188
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