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SDG goal 3: hepatitis

Abstract

Background

The World Health Organization European Action Plan 2020 targets for the elimination of viral hepatitis are that > 75% of eligible individuals with chronic hepatitis B (HBV) or hepatitis C (HCV) are treated, of whom > 90% achieve viral suppression.

Aim

To report the results from a pilot sentinel surveillance to monitor chronic HBV and HCV treatment uptake and outcomes in 2019.

Methods

We undertook retrospective enhanced data collection on patients with a confirmed chronic HBV or HCV infection presenting at one of seven clinics in three countries (Croatia, Romania and Spain) for the first time between 1 January 2019 and 30 June 2019. Clinical records were reviewed from date of first attendance to 31 December 2019 and data on sociodemographics, clinical history, laboratory results, treatment and treatment outcomes were collected. Treatment eligibility, uptake and case outcome were assessed.

Results

Of 229 individuals with chronic HBV infection, treatment status was reported for 203 (89%). Of the 80 individuals reported as eligible for treatment, 51% (41/80) were treated of whom 89% (33/37) had achieved viral suppression. Of 240 individuals with chronic HCV infection, treatment status was reported for 231 (96%). Of 231 eligible individuals, 77% (179/231) were treated, the majority of whom had received direct acting antivirals (99%, 174/176) and had achieved sustained virological response (98%, 165/169).

Conclusion

Treatment targets for global elimination were missed for HBV but not for HCV. A wider European implementation of sentinel surveillance with a representative sample of sites could help monitor progress towards achieving hepatitis control targets.

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This work is licensed under a Creative Commons Attribution 4.0 International License.
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2023-02-09
2024-12-22
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A pilot sentinel surveillance system to monitor treatment and treatment outcomes of chronic hepatitis B and C infections in clinical centres in three European countries, 2019
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Anthony+Nardone&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nardone Anthony</a>, <a href="/search?value1=Lina+Nerlander&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nerlander Lina</a>, <a href="/search?value1=Erika+Duffell&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Duffell Erika</a>, <a href="/search?value1=Marta+Valenciano&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Valenciano Marta</a>, <a href="/search?value1=Maria+Buti&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Buti Maria</a>, <a href="/search?value1=Cristina+Marcos-Fosch&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Marcos-Fosch Cristina</a>, <a href="/search?value1=Tatjana+Nemeth-Bla%C5%BEi%C4%87&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nemeth-Blažić Tatjana</a>, <a href="/search?value1=Odette+Popovici&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Popovici Odette</a>, <a href="/search?value1=Adriana+Vince&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Vince Adriana</a>, <a href="/search?value1=Petruta+Violeta+Filip&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Filip Petruta Violeta</a>, <a href="/search?value1=Tajana+Filipec&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Filipec Tajana</a>, <a href="/search?value1=Mirjana+Lana+Kosanovi%C4%87+Li%C4%8Dina&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kosanović Ličina Mirjana Lana</a>, <a href="/search?value1=Boris+Luksic&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Luksic Boris</a>, <a href="/search?value1=Diana+Nonkovi%C4%87&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nonković Diana</a>, <a href="/search?value1=Corina+Silvia+Pop&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pop Corina Silvia</a>, <a href="/search?value1=Fabiana+Radu&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Radu Fabiana</a>, <a href="/search?value1=Irina+Teodorescu&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Teodorescu Irina</a>, <a href="/search?value1=Adriana+Violeta+Topan&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Topan Adriana Violeta</a></span>. A pilot sentinel surveillance system to monitor treatment and treatment outcomes of chronic hepatitis B and C infections in clinical centres in three European countries, 2019. <a href="/content/ecdc">Euro Surveill.</a> 2023;28(6):pii=2200184. <a href="https://doi.org/10.2807/1560-7917.ES.2023.28.6.2200184" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2023.28.6.2200184</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 15 Feb 2022;&nbsp;&nbsp; <span class="generated">Accepted</span>: 19 Sept 2022 </span> </p>
/content/10.2807/1560-7917.ES.2023.28.6.2200184
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