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Abstract

We followed 4,081,257 Australian adults aged ≥ 65 years between November 2022 and May 2023 for COVID-19-specific mortality, when recombinant SARS-CoV-2 Omicron lineages (predominantly XB and XBB) as well as BA.2.75 were circulating. Compared with a COVID-19 booster targeting ancestral SARS-CoV-2 given > 180 days earlier, the relative vaccine effectiveness against COVID-19 death of a bivalent (ancestral/BA.1 or ancestral/BA.4-5) booster given 8 to 90 days earlier was 66.0% (95%CI: 57.6 to 72.2%) and that of a monovalent ancestral booster given 8 to 90 days earlier was 44.7% (95%CI: 23.9 to 59.7%).

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2023-11-23
2024-11-21
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2023.28.47.2300603
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Effectiveness of bivalent COVID-19 boosters against COVID-19 mortality in people aged 65 years and older, Australia, November 2022 to May 2023
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Bette+Liu&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Liu Bette</a>, <a href="/search?value1=Sandrine+Stepien&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Stepien Sandrine</a>, <a href="/search?value1=Ketaki+Sharma&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sharma Ketaki</a>, <a href="/search?value1=Kristine+Macartney&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Macartney Kristine</a></span>. Effectiveness of bivalent COVID-19 boosters against COVID-19 mortality in people aged 65 years and older, Australia, November 2022 to May 2023. <a href="/content/ecdc">Euro Surveill.</a> 2023;28(47):pii=2300603. <a href="https://doi.org/10.2807/1560-7917.ES.2023.28.47.2300603" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2023.28.47.2300603</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 02 Nov 2023;&nbsp;&nbsp; <span class="generated">Accepted</span>: 23 Nov 2023 </span> </p>
/content/10.2807/1560-7917.ES.2023.28.47.2300603
/content/10.2807/1560-7917.ES.2023.28.47.2300603
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