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Asymptomatic infection with clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) in carnivore pets, Italy, April 2023
- Ana Moreno1 , Francesco Bonfante2 , Alessio Bortolami2 , Irene Cassaniti3,4 , Anna Caruana8 , Vincenzo Cottini7 , Danilo Cereda5 , Marco Farioli5 , Alice Fusaro2 , Antonio Lavazza1 , Pierdavide Lecchini6 , Davide Lelli1 , Andrea Maroni Ponti6 , Claudia Nassuato7 , Ambra Pastori2 , Francesca Rovida3,4 , Luigi Ruocco6 , Marco Sordilli6 , Fausto Baldanti3,4,* , Calogero Terregino2,*
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View Affiliations Hide AffiliationsAffiliations: 1 Istituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna (IZSLER), Brescia, Italy 2 Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe), Legnaro (Padua), Italy 3 Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Pavia, Italy 4 SC Microbiology and Virology, IRCCS Policlinico San Matteo, Pavia, Italy 5 General Directorate of Welfare, Regione Lombardia, Milan, Italy 6 Sanità Animale e Farmaci Veterinari, Ministero della Salute, Rome, Italy 7 Dipartimento Veterinario e Sicurezza degli Alimenti di origine animale-ATS Brescia Direzione Generale, Brescia, Italy 8 Dipartimento di Igiene e Prevenzione Sanitaria-ATS Brescia, Brescia, Italy * These authors contributed equally to this work and share last authorship.Ana Morenoanamaria.morenomartin izsler.it
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Citation style for this article: Moreno Ana, Bonfante Francesco, Bortolami Alessio, Cassaniti Irene, Caruana Anna, Cottini Vincenzo, Cereda Danilo, Farioli Marco, Fusaro Alice, Lavazza Antonio, Lecchini Pierdavide, Lelli Davide, Maroni Ponti Andrea, Nassuato Claudia, Pastori Ambra, Rovida Francesca, Ruocco Luigi, Sordilli Marco, Baldanti Fausto, Terregino Calogero. Asymptomatic infection with clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) in carnivore pets, Italy, April 2023. Euro Surveill. 2023;28(35):pii=2300441. https://doi.org/10.2807/1560-7917.ES.2023.28.35.2300441 Received: 21 Aug 2023; Accepted: 31 Aug 2023
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Abstract
In April 2023, an outbreak of clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) viruses carrying the T271A mammalian adaptive mutation in the PB2 protein was detected in a backyard poultry farm in Italy. Five domestic dogs and one cat living on the premises had seroconverted in the absence of clinical signs. Virological and serological monitoring of individuals exposed to the virus proved the absence of human transmission, however, asymptomatic influenza A(H5N1) infections in mammalian pets may have important public health implications.
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