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Abstract

Measles cases have recently been increasing in Romania, with 460 confirmed cases by August 2023. From March 2023, measles cases increased, and outbreaks were recorded in Cluj, Bistrita Nasaud, Sibiu and Mures counties. New D8 virus variants were identified, different from the variants detected in Romania before the COVID-19 pandemic. We here provide epidemiological and molecular data on the current increase in measles cases in the context of the measles elimination process in the World Health Organization European Region.

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/content/10.2807/1560-7917.ES.2023.28.35.2300423
2023-08-31
2024-11-21
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2023.28.35.2300423
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References

  1. European Commission (EC). Commission implementing decision (EU) 2018/945 of 22 June 2018 on the communicable diseases and related special health issues to be covered by epidemiological surveillance as well as relevant case definitions. Brussels: EC; 2018. Available from: https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32018D0945&from=EN#page=30
  2. Stanescu A, Janta D, Lupulescu E, Necula G, Lazar M, Molnar G, et al. Ongoing measles outbreak in Romania, 2011. Euro Surveill. 2011;16(31):19932.  https://doi.org/10.2807/ese.16.31.19932-en  PMID: 21871218 
  3. Lazar M, Stănescu A, Penedos AR, Pistol A. Characterisation of measles after the introduction of the combined measles-mumps-rubella (MMR) vaccine in 2004 with focus on the laboratory data, 2016 to 2019 outbreak, Romania. Euro Surveill. 2019;24(29):1900041.  https://doi.org/10.2807/1560-7917.ES.2019.24.29.1900041  PMID: 31339098 
  4. Necula G, Lazar M, Stanescu A, Pistol A, Santibanez S, Mankertz A, et al. Transmission and molecular characterisation of wild measles virus in Romania, 2008 to 2012. Euro Surveill. 2013;18(50):20658.  https://doi.org/10.2807/1560-7917.ES2013.18.50.20658  PMID: 24342518 
  5. World Health Organization (WHO). Annex 7.1. Protocol for amplification of measles sequencing window (N-450). Geneva: WHO; 2015. Geneva: WHO; 2022. Available from: https://cdn.who.int/media/docs/default-source/immunization/vpd_surveillance/lab_networks/measles_rubella/manual/annex-7.1-protocol-for-amplification-of-measles-sequencing-window-(n-450).pdf?sfvrsn=b2f7886b_5
  6. Rota PA, Brown K, Mankertz A, Santibanez S, Shulga S, Muller CP, et al. Global distribution of measles genotypes and measles molecular epidemiology. J Infect Dis. 2011;204(Suppl 1):S514-23.  https://doi.org/10.1093/infdis/jir118  PMID: 21666208 
  7. Kumar S, Stecher G, Li M, Knyaz C, Tamura K. MEGA X: Molecular Evolutionary Genetics Analysis across computing platforms. Mol Biol Evol. 2018;35(6):1547-9.  https://doi.org/10.1093/molbev/msy096  PMID: 29722887 
  8. Genetic diversity of wild-type measles viruses and the global measles nucleotide surveillance database (MeaNS). Wkly Epidemiol Rec. 2015;90(30):373-80. PMID: 26211016 
  9. Benson DA, Cavanaugh M, Clark K, Karsch-Mizrachi I, Lipman DJ, Ostell J, et al. GenBank. Nucleic Acids Res. 2013;41(Database issue):D36-42. PMID: 23193287 
  10. World Health Organization (WHO). Chapter 7: Manual for the Laboratory-based Surveillance of Measles, Rubella, and Congenital Rubella Syndrome. Molecular epidemiology of measles and rubella. Geneva: WHO; 2018. Available from: https://www.who.int/publications/m/item/chapter-7-manual-for-the-laboratory-based-surveillance-of-measles-rubella-and-congenital-rubella-syndrome
  11. World Health Organization (WHO). Measles. Geneva: WHO; 2023. Available from: https://www.who.int/news-room/fact-sheets/detail/measles#:~:text=An%20estimated%20128%20000%20people,safe%20and%20cost%2Deffective%20vaccine
  12. World Health Organization (WHO). UNICEF and WHO warn of perfect storm of conditions for measles outbreaks, affecting children. Geneva: WHO; 2022. Available from: https://www.who.int/news/item/27-04-2022-unicef-and-who-warn-of--perfect-storm--of-conditions-for-measles-outbreaks--affecting-children
  13. World Health Organization (WHO). Countries in the European Region stepping up to stop the spread of measles as cases in 2023 already exceed all those in 2022. Geneva: WHO; 2023. Available from: https://www.who.int/europe/news/item/26-04-2023-countries-in-the-european-region-stepping-up-to-stop-the-spread-of-measles-as-cases-in-2023-already-exceed-all-those-in-2022
  14. World Health Organization (WHO). Measles vaccines: WHO position paper – April 2017. Wkly Epidemiol Rec. 2017;92(17):205-27. Available from: https://www.who.int/publications/i/item/who-wer9217-205-227 PMID: 28459148 
  15. Romanian National Institute of Public Health (INSP). Centrul National de Supraveghere si Control al Bolilor Transmisibile Informari saptamanale. [National Centre for Communicable Diseases Surveillance and Control, Weekly reports]. Bucharest: INSP. [Accessed: 18 Jun 2023]. Romanian. Available from: https://www.cnscbt.ro/index.php/analiza-date-supraveghere/evaluarea-acoperirii-vaccinale
  16. Dube E, Pistol A, Stanescu A, Butu C, Guirguis S, Motea O, et al. Vaccination barriers and drivers in Romania: a focused ethnographic study. Eur J Public Health. 2023;33(2):222-7.  https://doi.org/10.1093/eurpub/ckac135  PMID: 36416573 
  17. Habersaat KB, Pistol A, Stanescu A, Hewitt C, Grbic M, Butu C, et al. Measles outbreak in Romania: understanding factors related to suboptimal vaccination uptake. Eur J Public Health. 2020;30(5):986-92.  https://doi.org/10.1093/eurpub/ckaa079  PMID: 32460309 
  18. Hübschen JM, Gouandjika-Vasilache I, Dina J. Measles. Lancet. 2022;399(10325):678-90.  https://doi.org/10.1016/S0140-6736(21)02004-3  PMID: 35093206 
Ongoing measles outbreaks in Romania, March 2023 to August 2023
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Mihaela+Lazar&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lazar Mihaela</a>, <a href="/search?value1=C%C4%83t%C4%83lina+Pascu&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pascu Cătălina</a>, <a href="/search?value1=Maria+Ro%C8%99ca&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Roșca Maria</a>, <a href="/search?value1=Aurora+St%C4%83nescu&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Stănescu Aurora</a></span>. Ongoing measles outbreaks in Romania, March 2023 to August 2023. <a href="/content/ecdc">Euro Surveill.</a> 2023;28(35):pii=2300423. <a href="https://doi.org/10.2807/1560-7917.ES.2023.28.35.2300423" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2023.28.35.2300423</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 09 Aug 2023;&nbsp;&nbsp; <span class="generated">Accepted</span>: 30 Aug 2023 </span> </p>
/content/10.2807/1560-7917.ES.2023.28.35.2300423
/content/10.2807/1560-7917.ES.2023.28.35.2300423
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