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Abstract

Vaccination is important in containing the 2022 mpox (formerly monkeypox) epidemic. We describe five Belgian patients with localised severe symptoms of proctitis and penile oedema, occurring between 4 and 35 days after post-exposure preventive vaccination or after one- or two-dose off-label pre-exposure preventive vaccination with MVA-BN vaccine. Genome sequencing did not reveal evidence for immune escape variants. Healthcare workers and those at risk should be aware of possible infections occurring shortly after vaccination and the need for other preventive measures.

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/content/10.2807/1560-7917.ES.2022.27.48.2200894
2022-12-01
2024-11-22
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2022.27.48.2200894
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Severe mpox (formerly monkeypox) disease in five patients after recent vaccination with MVA-BN vaccine, Belgium, July to October 2022
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Nicole+Berens-Riha&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Berens-Riha Nicole</a>, <a href="/search?value1=Tessa+De+Block&option1=author&noRedirect=true" class="nonDisambigAuthorLink">De Block Tessa</a>, <a href="/search?value1=Jojanneke+Rutgers&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rutgers Jojanneke</a>, <a href="/search?value1=Johan+Michiels&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Michiels Johan</a>, <a href="/search?value1=Liesbeth+Van+Gestel&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Van Gestel Liesbeth</a>, <a href="/search?value1=Matilde+Hens&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hens Matilde</a>, <a href="/search?value1=ITM+monkeypox+study+group&option1=author&noRedirect=true" class="nonDisambigAuthorLink">ITM monkeypox study group</a>, <a href="/search?value1=Chris+Kenyon&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kenyon Chris</a>, <a href="/search?value1=Emmanuel+Bottieau&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bottieau Emmanuel</a>, <a href="/search?value1=Patrick+Soentjens&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Soentjens Patrick</a>, <a href="/search?value1=Johan+van+Griensven&option1=author&noRedirect=true" class="nonDisambigAuthorLink">van Griensven Johan</a>, <a href="/search?value1=Isabel+Brosius&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Brosius Isabel</a>, <a href="/search?value1=Kevin+K+Ari%C3%ABn&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ariën Kevin K</a>, <a href="/search?value1=Marjan+Van+Esbroeck&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Van Esbroeck Marjan</a>, <a href="/search?value1=Antonio+Mauro+Rezende&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rezende Antonio Mauro</a>, <a href="/search?value1=Koen+Vercauteren&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Vercauteren Koen</a>, <a href="/search?value1=Laurens+Liesenborghs&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Liesenborghs Laurens</a></span>. Severe mpox (formerly monkeypox) disease in five patients after recent vaccination with MVA-BN vaccine, Belgium, July to October 2022. <a href="/content/ecdc">Euro Surveill.</a> 2022;27(48):pii=2200894. <a href="https://doi.org/10.2807/1560-7917.ES.2022.27.48.2200894" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2022.27.48.2200894</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 21 Nov 2022;&nbsp;&nbsp; <span class="generated">Accepted</span>: 01 Dec 2022 </span> </p>
/content/10.2807/1560-7917.ES.2022.27.48.2200894
/content/10.2807/1560-7917.ES.2022.27.48.2200894
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