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Abstract

We describe a gonorrhoea case with ceftriaxone plus high-level azithromycin resistance. In April 2022, an Austrian heterosexual male was diagnosed with gonorrhoea after sexual intercourse with a female sex worker in Cambodia. Recommended treatment with ceftriaxone (1 g) plus azithromycin (1.5 g) possibly failed. Worryingly, this is the second strain in an Asian genomic sublineage including high-level azithromycin-resistant strains that developed ceftriaxone resistance by acquisition of mosaic -60.001. Enhanced resistance surveillance and actions are imperative to prevent spread.

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/content/10.2807/1560-7917.ES.2022.27.24.2200455
2022-06-16
2024-11-21
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2022.27.24.2200455
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Extensively drug-resistant (XDR) Neisseria gonorrhoeae causing possible gonorrhoea treatment failure with ceftriaxone plus azithromycin in Austria, April 2022
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Sonja+Pleininger&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pleininger Sonja</a>, <a href="/search?value1=Alexander+Indra&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Indra Alexander</a>, <a href="/search?value1=Daniel+Golparian&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Golparian Daniel</a>, <a href="/search?value1=Florian+Heger&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Heger Florian</a>, <a href="/search?value1=Stefanie+Schindler&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Schindler Stefanie</a>, <a href="/search?value1=Susanne+Jacobsson&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Jacobsson Susanne</a>, <a href="/search?value1=Stefan+Heidler&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Heidler Stefan</a>, <a href="/search?value1=Magnus+Unemo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Unemo Magnus</a></span>. Extensively drug-resistant (XDR) Neisseria gonorrhoeae causing possible gonorrhoea treatment failure with ceftriaxone plus azithromycin in Austria, April 2022. <a href="/content/ecdc">Euro Surveill.</a> 2022;27(24):pii=2200455. <a href="https://doi.org/10.2807/1560-7917.ES.2022.27.24.2200455" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2022.27.24.2200455</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 07 Jun 2022;&nbsp;&nbsp; <span class="generated">Accepted</span>: 14 Jun 2022 </span> </p>
/content/10.2807/1560-7917.ES.2022.27.24.2200455
/content/10.2807/1560-7917.ES.2022.27.24.2200455
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