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Abstract

Two London care homes experienced a second COVID-19 outbreak, with 29/209 (13.9%) SARS-CoV-2 RT-PCR-positive cases (16/103 residents, 13/106 staff). In those with prior SARS-CoV-2 exposure, 1/88 (1.1%) individuals (antibody positive: 87; RT-PCR-positive: 1) became PCR-positive compared with 22/73 (30.1%) with confirmed seronegative status. After four months protection offered by prior infection against re-infection was 96.2% (95% confidence interval (CI): 72.7–99.5%) using risk ratios from comparison of proportions and 96.1% (95% CI: 78.8–99.3%) using a penalised logistic regression model.

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/content/10.2807/1560-7917.ES.2021.26.5.2100092
2021-02-04
2024-12-22
/content/10.2807/1560-7917.ES.2021.26.5.2100092
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Antibodies to SARS-CoV-2 protect against re-infection during outbreaks in care homes, September and October 2020
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Anna+Jeffery-Smith&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Jeffery-Smith Anna</a>, <a href="/search?value1=Nalini+Iyanger&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Iyanger Nalini</a>, <a href="/search?value1=Sarah+V+Williams&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Williams Sarah V</a>, <a href="/search?value1=J+Yimmy+Chow&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Chow J Yimmy</a>, <a href="/search?value1=Felicity+Aiano&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Aiano Felicity</a>, <a href="/search?value1=Katja+Hoschler&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hoschler Katja</a>, <a href="/search?value1=Angie+Lackenby&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lackenby Angie</a>, <a href="/search?value1=Joanna+Ellis&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ellis Joanna</a>, <a href="/search?value1=Steven+Platt&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Platt Steven</a>, <a href="/search?value1=Shahjahan+Miah&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Miah Shahjahan</a>, <a href="/search?value1=Kevin+Brown&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Brown Kevin</a>, <a href="/search?value1=Gayatri+Amirthalingam&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Amirthalingam Gayatri</a>, <a href="/search?value1=Monika+Patel&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Patel Monika</a>, <a href="/search?value1=Mary+E+Ramsay&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ramsay Mary E</a>, <a href="/search?value1=Robin+Gopal&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gopal Robin</a>, <a href="/search?value1=Andre+Charlett&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Charlett Andre</a>, <a href="/search?value1=Shamez+N+Ladhani&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ladhani Shamez N</a>, <a href="/search?value1=Maria+Zambon&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Zambon Maria</a></span>. Antibodies to SARS-CoV-2 protect against re-infection during outbreaks in care homes, September and October 2020. <a href="/content/ecdc">Euro Surveill.</a> 2021;26(5):pii=2100092. <a href="https://doi.org/10.2807/1560-7917.ES.2021.26.5.2100092" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2021.26.5.2100092</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 23 Jan 2021;&nbsp;&nbsp; <span class="generated">Accepted</span>: 04 Feb 2021 </span> </p>
/content/10.2807/1560-7917.ES.2021.26.5.2100092
/content/10.2807/1560-7917.ES.2021.26.5.2100092
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