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Product-specific COVID-19 vaccine effectiveness against secondary infection in close contacts, Navarre, Spain, April to August 2021
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View Affiliations Hide AffiliationsJesús Castillajcastilc navarra.es
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Investigators, other members of the Working Group for the Study of COVID-19 in Navarre: Carmen Martín, Isabel Polo, Amaya Bacaicoa, Judith Chamorro, Juana Vidán, Ingrid Estévez, Igberto Tordoya, Delia Quílez, Francisco Lameiro, Ana Isabel Álvaro, Esther Albéniz, Aitziber Echeverría, Paula López Moreno, Javier Gorricho, Eva Ardanaz, Maite Arriazu, Fernando Baigorria, Aurelio Barricarte, Enrique de la Cruz, Jorge Díaz, Nerea Egüés, Manuel García Cenoz, Nerea Iriarte, Kenya Nekotxea, Conchi Moreno-Iribas, Carmen Sayón, Maitane Tellechea, Marian NuínView Citation Hide Citation
Citation style for this article: . Product-specific COVID-19 vaccine effectiveness against secondary infection in close contacts, Navarre, Spain, April to August 2021. Euro Surveill. 2021;26(39):pii=2100894. https://doi.org/10.2807/1560-7917.ES.2021.26.39.2100894 Received: 15 Sept 2021; Accepted: 30 Sept 2021
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Abstract
COVID-19 vaccine effectiveness by product (two doses Comirnaty, Spikevax or Vaxzevria and one of Janssen), against infection ranged from 50% (95% CI: 42 to 57) for Janssen to 86% (70 to 93) for Vaxzevria-Comirnaty combination; among ≥ 60 year-olds, from 17% (−26 to 45) for Janssen to 68% (48 to 80) for Spikevax; and against hospitalisation from 74% (43 to 88) for Janssen to > 90% for other products. Two doses of vaccine were highly effective against hospitalisation, but suboptimal for infection control.
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