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Abstract

We analysed 9,030 variant-specific RT-PCR tests performed on SARS-CoV-2-positive samples collected in France between 31 May and 21 June 2021. This analysis revealed rapid growth of the Delta variant in three of the 13 metropolitan French regions and estimated a +79% (95% confidence interval: 52–110%) transmission advantage compared with the Alpha variant. The next weeks will prove decisive and the magnitude of the estimated transmission advantages of the Delta variant could represent a major challenge for public health authorities.

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/content/10.2807/1560-7917.ES.2021.26.28.2100573
2021-07-15
2024-12-30
/content/10.2807/1560-7917.ES.2021.26.28.2100573
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References

  1. Davies NG, Abbott S, Barnard RC, Jarvis CI, Kucharski AJ, Munday JD, et al. Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England. Science. 2021;372(6538):eabg3055.  https://doi.org/10.1126/science.abg3055  PMID: 33658326 
  2. Volz E, Mishra S, Chand M, Barrett JC, Johnson R, Geidelberg L, et al. Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England. Nature. 2021;593(7858):266-9.  https://doi.org/10.1038/s41586-021-03470-x  PMID: 33767447 
  3. Faria NR, Mellan TA, Whittaker C, Claro IM, Candido DDS, Mishra S, et al. Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil. Science. 2021;372(6544):815-21.  https://doi.org/10.1126/science.abh2644  PMID: 33853970 
  4. Tegally H, Wilkinson E, Giovanetti M, Iranzadeh A, Fonseca V, Giandhari J, et al. Detection of a SARS-CoV-2 variant of concern in South Africa. Nature. 2021;592(7854):438-43.  https://doi.org/10.1038/s41586-021-03402-9  PMID: 33690265 
  5. World Health Organization (WHO). Tracking SARS-CoV-2 variants. Geneva: WHO. [Accessed: 1 Jul 2021]. Available from: https://www.who.int/en/activities/tracking-SARS-CoV-2-variants
  6. Public Health England (PHE). SARS-CoV-2 variants of concern and variants under investigation in England. Technical briefing 14. London: PHS. [Accessed: 3 Jun 2021]. Available from: https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/991343/Variants_of_Concern_VOC_Technical_Briefing_14.pdf
  7. Public Health England (PHE). SARS-CoV-2 variants of concern and variants under investigation - Technical briefing 15; London: PHE; 2021. Available from: https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/993879/Variants_of_Concern_VOC_Technical_Briefing_15.pdf
  8. Bernal JL, Andrews N, Gower C, Gallagher E, Simmons R, Thelwall S, et al. Effectiveness of COVID-19 vaccines against the B.1.617.2 variant. medRxiv. 2021;p.2021.05.22.21257658  https://doi.org/10.1101/2021.05.22.21257658 
  9. Haim-Boukobza S, Roquebert B, Trombert-Paolantoni S, Lecorche E, Verdurme L, Foulongne V, et al. Detecting rapid spread of SARS-CoV-2 variants, France, January 26-February 16, 2021. Emerg Infect Dis. 2021;27(5):1496-9.  https://doi.org/10.3201/eid2705.210397  PMID: 33769253 
  10. Gaymard A, Bosetti P, Feri A, Destras G, Enouf V, Andronico A, et al. Early assessment of diffusion and possible expansion of SARS-CoV-2 Lineage 20I/501Y.V1 (B.1.1.7, variant of concern 202012/01) in France, January to March 2021. Euro Surveill. 2021;26(9):2100133.  https://doi.org/10.2807/1560-7917.ES.2021.26.9.2100133  PMID: 33663644 
  11. Rambaut A, Holmes EC, O’Toole Á, Hill V, McCrone JT, Ruis C, et al. A dynamic nomenclature proposal for SARS-CoV-2 lineages to assist genomic epidemiology. Nat Microbiol. 2020;5(11):1403-7.  https://doi.org/10.1038/s41564-020-0770-5  PMID: 32669681 
  12. Santé Publique France. Analyse de risque sur les variants émergents du SARS-CoV-2 réalisée conjointe-ment par Santé publique France et le CNR des virus des infections respiratoires. Mise à jour du 30/06/2021. [SARS-CoV-2 emerging variant risk analysis jointly realised by French public health national agency (Santé Publique France) and the national reference center (Centre National de Référence) for respiratory infection viruses]. Saint-Maurice cedex: Santé Publique France. [Accessed: 14 Jul 2021]. French. Available from: https://www.santepubliquefrance.fr/media/files/01-maladies-et-traumatismes/maladies-et-infections-respiratoires/infection-a-coronavirus/analyse-de-risque-des-variants-emergents-de-sars-cov-2-30-06-21
  13. Roquebert B, Trombert-Paolantoni S, Haim-Boukobza S, Lecorche E, Verdurme L, Foulongne V, et al. The SARS-CoV-2 B.1.351 lineage (VOC β) is outgrowing the B.1.1.7 lineage (VOC α) in some French regions in April 2021. Euro Surveill. 2021;26(23):2100447.  https://doi.org/10.2807/1560-7917.ES.2021.26.23.2100447  PMID: 34114541 
  14. Chevin LM. On measuring selection in experimental evolution. Biol Lett. 2011;7(2):210-3.  https://doi.org/10.1098/rsbl.2010.0580  PMID: 20810425 
  15. Sofonea MT, Reyné B, Elie B, Djidjou-Demasse R, Selinger C, Michalakis Y, et al. Memory is key in capturing COVID-19 epidemiological dynamics. Epidemics. 2021;35:100459.  https://doi.org/10.1016/j.epidem.2021.100459  PMID: 34015676 
  16. Santé Publique France. Quelle est l’évolution moléculaire des virus SARS-CoV-2 circulant sur le terri-toire? Résultats de l’enquête Flash#9. [What is the molecular evolution of SARS-CoV-2 viruses circulat-ing in the territory? Flash survey results # 9]. Saint-Maurice cedex: Santé Publique France. [Accessed: 16 Jun 2021]. French. Available from: https://www.santepubliquefrance.fr/maladies-et-traumatismes/maladies-et-infections-respiratoires/infection-a-coronavirus/documents/enquetes-etudes/quelle-est-l-evolution-moleculaire-des-virus-sars-cov-2-circulant-sur-le-territoire-resultats-de-l-enquete-flash-9
  17. Campbell F, Archer B, Laurenson-Schafer H, Jinnai Y, Konings F, Batra N, et al. Increased transmissibility and global spread of SARS-CoV-2 variants of concern as at June 2021. Euro Surveill. 2021;26(24):2100509.  https://doi.org/10.2807/1560-7917.ES.2021.26.24.2100509  PMID: 34142653 
Rapid spread of the SARS-CoV-2 Delta variant in some French regions, June 2021
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Samuel+Alizon&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Alizon Samuel</a>, <a href="/search?value1=St%C3%A9phanie+Haim-Boukobza&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Haim-Boukobza Stéphanie</a>, <a href="/search?value1=Vincent+Foulongne&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Foulongne Vincent</a>, <a href="/search?value1=Laura+Verdurme&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Verdurme Laura</a>, <a href="/search?value1=Sabine+Trombert-Paolantoni&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Trombert-Paolantoni Sabine</a>, <a href="/search?value1=Emmanuel+Lecorche&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lecorche Emmanuel</a>, <a href="/search?value1=B%C3%A9n%C3%A9dicte+Roquebert&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Roquebert Bénédicte</a>, <a href="/search?value1=Mircea+T.+Sofonea&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sofonea Mircea T.</a></span>. Rapid spread of the SARS-CoV-2 Delta variant in some French regions, June 2021. <a href="/content/ecdc">Euro Surveill.</a> 2021;26(28):pii=2100573. <a href="https://doi.org/10.2807/1560-7917.ES.2021.26.28.2100573" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2021.26.28.2100573</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 17 Jun 2021;&nbsp;&nbsp; <span class="generated">Accepted</span>: 15 Jul 2021 </span> </p>
/content/10.2807/1560-7917.ES.2021.26.28.2100573
/content/10.2807/1560-7917.ES.2021.26.28.2100573
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