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Abstract

COVID-19 vaccine effectiveness was evaluated in close contacts of cases diagnosed during January–April 2021. Among 20,961 contacts, 7,240 SARS-CoV-2 infections were confirmed, with 5,467 being symptomatic and 559 leading to hospitalisations. Non-brand-specific one and two dose vaccine effectiveness were respectively, 35% (95% confidence interval (CI): 25 to 44) and 66% (95% CI: 57 to 74) against infections, 42% (95% CI: 31 to 52) and 82% (95% CI: 74 to 88) against symptomatic infection, and 72% (95% CI: 47 to 85) and 95% (95% CI: 62 to 99) against COVID-19 hospitalisation. The second dose significantly increased effectiveness. Findings support continuing complete vaccination.

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/content/10.2807/1560-7917.ES.2021.26.21.2100438
2021-05-27
2024-11-28
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2021.26.21.2100438
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Effectiveness of COVID-19 vaccines in preventing SARS-CoV-2 infection and hospitalisation, Navarre, Spain, January to April 2021
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Iv%C3%A1n+Mart%C3%ADnez-Baz&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Martínez-Baz Iván</a>, <a href="/search?value1=Ana+Miqueleiz&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Miqueleiz Ana</a>, <a href="/search?value1=Itziar+Casado&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Casado Itziar</a>, <a href="/search?value1=Ana+Navascu%C3%A9s&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Navascués Ana</a>, <a href="/search?value1=Camino+Trobajo-Sanmart%C3%ADn&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Trobajo-Sanmartín Camino</a>, <a href="/search?value1=Cristina+Burgui&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Burgui Cristina</a>, <a href="/search?value1=Marcela+Guevara&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Guevara Marcela</a>, <a href="/search?value1=Carmen+Ezpeleta&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ezpeleta Carmen</a>, <a href="/search?value1=Jes%C3%BAs+Castilla&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Castilla Jesús</a>, <a href="/search?value1=Working+Group+for+the+Study+of+COVID-19+in+Navarra&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Working Group for the Study of COVID-19 in Navarra</a></span>. Effectiveness of COVID-19 vaccines in preventing SARS-CoV-2 infection and hospitalisation, Navarre, Spain, January to April 2021. <a href="/content/ecdc">Euro Surveill.</a> 2021;26(21):pii=2100438. <a href="https://doi.org/10.2807/1560-7917.ES.2021.26.21.2100438" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2021.26.21.2100438</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 11 May 2021;&nbsp;&nbsp; <span class="generated">Accepted</span>: 27 May 2021 </span> </p>
/content/10.2807/1560-7917.ES.2021.26.21.2100438
/content/10.2807/1560-7917.ES.2021.26.21.2100438
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