1887
  1. Home
  2. Eurosurveillance
  3. Volume 26, Issue 21, 27/May/2021
  4. Article
Rapid communication Open Access
Like 0
Download

Abstract

We investigated three SARS-CoV-2 variant B.1.1.7 childcare centre and related household outbreaks. Despite group cohorting, cases occurred in almost all groups, i.e. also among persons without close contact. Children’s secondary attack rates (SAR) were similar to adults (childcare centres: 23% vs 30%; p = 0.15; households: 32% vs 39%; p = 0.27); child- and adult-induced household outbreaks also led to similar SAR. With the advent of B.1.1.7, susceptibility and infectiousness of children and adults seem to converge. Public health measures should be revisited accordingly.

© Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Loading

Article metrics loading...

/content/10.2807/1560-7917.ES.2021.26.21.2100433
2021-05-27
2024-11-21
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2021.26.21.2100433
Loading
Loading full text...

Full text loading...

/deliver/fulltext/eurosurveillance/26/21/eurosurv-26-21-1.html?itemId=/content/10.2807/1560-7917.ES.2021.26.21.2100433&mimeType=html&fmt=ahah

References

  1. Robert Koch-Institut (RKI). Bericht zu Virusvarianten von SARS-CoV-2 in Deutschland, insbesondere zur Variant of Concern (VOC) B.1.1.7, Stand 03.März 2021. [Report about variants of SARS-CoV-2 in Germany, particularly the variant of concern (VOC) B.1.1.7, status: 3 March 2021]. Berlin: RKI. [Accessed: 12 Mar 2021]. German. Available from: https://www.rki.de/DE/Content/InfAZ/N/Neuartiges_Coronavirus/DESH/Bericht_VOC_2021-03-03.pdf?__blob=publicationFile
  2. Davies NG, Barnard RC, Jarvis CI, Kucharski AJ, Munday J, Pearson CAB, et al. Estimated transmissibility and severity of novel SARS-CoV-2 Variant of Concern 202012/01 in England. medRxiv. 20 Dec 2020.  https://doi.org/10.1101/2020.12.24.20248822 
  3. Walker AS, Vihta K-D, Gethings O, Pritchard E, Jones J, House T, et al. Increased infections, but not viral burden, with a new SARS-CoV-2 variant. medRxiv. 15 Jan 2021.  https://doi.org/10.1101/2021.01.13.21249721 
  4. Graham MS, Sudre CH, May A, Antonelli M, Murray B, Varsavsky T, et al. The effect of SARS-CoV-2 variant B.1.1.7 on symptomatology, re-infection and transmissibility. medRxiv. 29 Jan 2021.  https://doi.org/10.1101/2021.01.28.21250680 
  5. Public Health England (PHE). Investigation of novel SARS-CoV-2 variant - Variant of Concern 202012/01 - Technical briefing 3. London: PHE. [Accessed: 15 May 2021]. Available from: https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/959360/Variant_of_Concern_VOC_202012_01_Technical_Briefing_3.pdf
  6. Lyngse FP, Mølbak K, Skov RL, Christiansen LE, Albertsen M, Møller CH, et al. Increased transmissibility of SARS-CoV-2 lineage by age and viral load: evidence from Danish households. 19 Apr 2021. medRxiv.  https://doi.org/10.1101/2021.04.16.21255459 
  7. Böhmer MM, Buchholz U, Corman VM, Hoch M, Katz K, Marosevic DV, et al. Investigation of a COVID-19 outbreak in Germany resulting from a single travel-associated primary case: a case series. Lancet Infect Dis. 2020;20(8):920-8.  https://doi.org/10.1016/S1473-3099(20)30314-5  PMID: 32422201 
  8. Chu DK, Akl EA, Duda S, Solo K, Yaacoub S, Schünemann HJ, et al. Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis. Lancet. 2020;395(10242):1973-87.  https://doi.org/10.1016/S0140-6736(20)31142-9  PMID: 32497510 
  9. Viner RM, Mytton OT, Bonell C, Melendez-Torres GJ, Ward J, Hudson L, et al. Susceptibility to SARS-CoV-2 Infection Among Children and Adolescents Compared With Adults: A Systematic Review and Meta-analysis. JAMA Pediatr. 2021;175(2):143-56.  https://doi.org/10.1001/jamapediatrics.2020.4573  PMID: 32975552 
  10. Koh WC, Naing L, Rosledzana MA, Alikhan MF, Chaw L, Griffith M, et al. What do we know about SARS-CoV-2 transmission? A systematic review and meta-analysis of the secondary attack rate, serial interval, and asymptomatic infection. 23 May 2020. medRxiv.  https://doi.org/10.1101/2020.05.21.20108746 
  11. Madewell ZJ, Yang Y, Longini IM Jr, Halloran ME, Dean NE. Household Transmission of SARS-CoV-2: A Systematic Review and Meta-analysis. JAMA Netw Open. 2020;3(12):e2031756.  https://doi.org/10.1001/jamanetworkopen.2020.31756  PMID: 33315116 
SARS-CoV-2 variant B.1.1.7 susceptibility and infectiousness of children and adults deduced from investigations of childcare centre outbreaks, Germany, 2021
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Anna+Loenenbach&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Loenenbach Anna</a>, <a href="/search?value1=Inessa+Markus&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Markus Inessa</a>, <a href="/search?value1=Ann-Sophie+Lehfeld&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lehfeld Ann-Sophie</a>, <a href="/search?value1=Matthias+an+der+Heiden&option1=author&noRedirect=true" class="nonDisambigAuthorLink">an der Heiden Matthias</a>, <a href="/search?value1=Walter+Haas&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Haas Walter</a>, <a href="/search?value1=Maya+Kiegele&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kiegele Maya</a>, <a href="/search?value1=Andr%C3%A9+Ponzi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ponzi André</a>, <a href="/search?value1=Barbara+Unger-Goldinger&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Unger-Goldinger Barbara</a>, <a href="/search?value1=Cornelius+Weidenauer&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Weidenauer Cornelius</a>, <a href="/search?value1=Helen+Schlosser&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Schlosser Helen</a>, <a href="/search?value1=Alexander+Beile&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Beile Alexander</a>, <a href="/search?value1=Udo+Buchholz&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Buchholz Udo</a></span>. SARS-CoV-2 variant B.1.1.7 susceptibility and infectiousness of children and adults deduced from investigations of childcare centre outbreaks, Germany, 2021. <a href="/content/ecdc">Euro Surveill.</a> 2021;26(21):pii=2100433. <a href="https://doi.org/10.2807/1560-7917.ES.2021.26.21.2100433" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2021.26.21.2100433</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 03 May 2021;&nbsp;&nbsp; <span class="generated">Accepted</span>: 26 May 2021 </span> </p>
/content/10.2807/1560-7917.ES.2021.26.21.2100433
/content/10.2807/1560-7917.ES.2021.26.21.2100433
Loading

Data & Media loading...

Submit comment
Close
Comment moderation successfully completed
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error