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Abstract

Two new SARS-CoV-2 lineages with the N501Y mutation in the receptor-binding domain of the spike protein spread rapidly in the United Kingdom. We estimated that the earlier 501Y lineage without amino acid deletion Δ69/Δ70, circulating mainly between early September and mid-November, was 10% (6–13%) more transmissible than the 501N lineage, and the 501Y lineage with amino acid deletion Δ69/Δ70, circulating since late September, was 75% (70–80%) more transmissible than the 501N lineage.

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An addendum has been published for this content:
Addendum for Euro Surveill. 2021;26(1)
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/content/10.2807/1560-7917.ES.2020.26.1.2002106
2021-01-07
2024-12-21
/content/10.2807/1560-7917.ES.2020.26.1.2002106
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Early transmissibility assessment of the N501Y mutant strains of SARS-CoV-2 in the United Kingdom, October to November 2020
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Kathy+Leung&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Leung Kathy</a>, <a href="/search?value1=Marcus+HH+Shum&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Shum Marcus HH</a>, <a href="/search?value1=Gabriel+M+Leung&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Leung Gabriel M</a>, <a href="/search?value1=Tommy+TY+Lam&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lam Tommy TY</a>, <a href="/search?value1=Joseph+T+Wu&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Wu Joseph T</a></span>. Early transmissibility assessment of the N501Y mutant strains of SARS-CoV-2 in the United Kingdom, October to November 2020. <a href="/content/ecdc">Euro Surveill.</a> 2021;26(1):pii=2002106. <a href="https://doi.org/10.2807/1560-7917.ES.2020.26.1.2002106" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2020.26.1.2002106</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 20 Dec 2020;&nbsp;&nbsp; <span class="generated">Accepted</span>: 28 Dec 2020 </span> </p>
/content/10.2807/1560-7917.ES.2020.26.1.2002106
/content/10.2807/1560-7917.ES.2020.26.1.2002106
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