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Abstract

Annually, increasing numbers of OXA-244-producing in 13 German federal states prompted us to initiate an outbreak investigation. Whole genome sequencing revealed that among 148 isolates analysed, most belonged to sequence type 38 with 62 isolates forming a genetically distinct cluster. Although no epidemiological link could be identified between cases, ongoing investigations suggest non-healthcare associated transmission. A screening-PCR was developed facilitating early detection of ST38 cluster isolates to identify the source and transmission route.

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/content/10.2807/1560-7917.ES.2020.25.25.2000923
2020-06-25
2024-11-16
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2020.25.25.2000923
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Rapid spread of OXA-244-producing Escherichia coli ST38 in Germany: insights from an integrated molecular surveillance approach; 2017 to January 2020
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Katrin+Kremer&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kremer Katrin</a>, <a href="/search?value1=Rolf+Kramer&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kramer Rolf</a>, <a href="/search?value1=Bernd+Neumann&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Neumann Bernd</a>, <a href="/search?value1=Sebastian+Haller&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Haller Sebastian</a>, <a href="/search?value1=Niels+Pfennigwerth&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pfennigwerth Niels</a>, <a href="/search?value1=Guido+Werner&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Werner Guido</a>, <a href="/search?value1=S%C3%B6ren+Gatermann&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gatermann Sören</a>, <a href="/search?value1=Horst+Schroten&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Schroten Horst</a>, <a href="/search?value1=Tim+Eckmanns&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Eckmanns Tim</a>, <a href="/search?value1=J%C3%B6rg+B+Hans&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hans Jörg B</a></span>. Rapid spread of OXA-244-producing Escherichia coli ST38 in Germany: insights from an integrated molecular surveillance approach; 2017 to January 2020. <a href="/content/ecdc">Euro Surveill.</a> 2020;25(25):pii=2000923. <a href="https://doi.org/10.2807/1560-7917.ES.2020.25.25.2000923" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2020.25.25.2000923</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 13 May 2020;&nbsp;&nbsp; <span class="generated">Accepted</span>: 25 Jun 2020 </span> </p>
/content/10.2807/1560-7917.ES.2020.25.25.2000923
/content/10.2807/1560-7917.ES.2020.25.25.2000923
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