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The cost of insecurity: from flare-up to control of a major Ebola virus disease hotspot during the outbreak in the Democratic Republic of the Congo, 2019
- Thibaut Jombart1,2,3,4 , Christopher I Jarvis1,2,4 , Samuel Mesfin5 , Nabil Tabal5 , Mathias Mossoko6 , Luigino Minikulu Mpia6 , Aaron Aruna Abedi6 , Sonia Chene5 , Ekokobe Elias Forbin5 , Marie Roseline D Belizaire5 , Xavier de Radiguès5 , Richy Ngombo5 , Yannick Tutu6 , Flavio Finger1,4 , Madeleine Crowe5 , W John Edmunds1 , Justus Nsio6 , Abdoulaye Yam5 , Boubacar Diallo5 , Abdou Salam Gueye5 , Steve Ahuka-Mundeke7 , Michel Yao5 , Ibrahima Socé Fall5
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View Affiliations Hide AffiliationsAffiliations: 1 Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom 2 UK Public Health Rapid Support Team, London, United Kingdom 3 MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom 4 Global Outbreak Alert and Response Network, Geneva, Switzerland 5 World Health Organization, Geneva, Switzerland 6 Ministère de la Santé Publique, Kinshasa, Democratic Republic of the Congo 7 Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the CongoThibaut Jombartthibautjombart gmail.com
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Citation style for this article: Jombart Thibaut, Jarvis Christopher I, Mesfin Samuel, Tabal Nabil, Mossoko Mathias, Mpia Luigino Minikulu, Abedi Aaron Aruna, Chene Sonia, Forbin Ekokobe Elias, Belizaire Marie Roseline D, de Radiguès Xavier, Ngombo Richy, Tutu Yannick, Finger Flavio, Crowe Madeleine, Edmunds W John, Nsio Justus, Yam Abdoulaye, Diallo Boubacar, Gueye Abdou Salam, Ahuka-Mundeke Steve, Yao Michel, Fall Ibrahima Socé. The cost of insecurity: from flare-up to control of a major Ebola virus disease hotspot during the outbreak in the Democratic Republic of the Congo, 2019. Euro Surveill. 2020;25(2):pii=1900735. https://doi.org/10.2807/1560-7917.ES.2020.25.2.1900735 Received: 03 Dec 2019; Accepted: 15 Jan 2020
Abstract
The ongoing Ebola outbreak in the eastern Democratic Republic of the Congo is facing unprecedented levels of insecurity and violence. We evaluate the likely impact in terms of added transmissibility and cases of major security incidents in the Butembo coordination hub. We also show that despite this additional burden, an adapted response strategy involving enlarged ring vaccination around clusters of cases and enhanced community engagement managed to bring this main hotspot under control.
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References
-
Aylward B, Barboza P, Bawo L, Bertherat E, Bilivogui P, Blake I, et al. Ebola virus disease in West Africa--the first 9 months of the epidemic and forward projections. N Engl J Med. 2014;371(16):1481-95. https://doi.org/10.1056/NEJMoa1411100 PMID: 25244186
-
Agua-Agum J, Ariyarajah A, Aylward B, Bawo L, Bilivogui P, Blake IM, et al. Exposure patterns driving Ebola transmission in West Africa: a retrospective observational study. PLoS Med. 2016;13(11):e1002170. https://doi.org/10.1371/journal.pmed.1002170 PMID: 27846234
-
Agua-Agum J, Ariyarajah A, Aylward B, Blake IM, Brennan R, Cori A, et al. West African Ebola epidemic after one year--slowing but not yet under control. N Engl J Med. 2015;372(6):584-7. https://doi.org/10.1056/NEJMc1414992 PMID: 25539446
-
Heymann DL, Chen L, Takemi K, Fidler DP, Tappero JW, Thomas MJ, et al. Global health security: the wider lessons from the west African Ebola virus disease epidemic. Lancet. 2015;385(9980):1884-901. https://doi.org/10.1016/S0140-6736(15)60858-3 PMID: 25987157
-
Coltart CEM, Lindsey B, Ghinai I, Johnson AM, Heymann DL. The Ebola outbreak, 2013-2016: old lessons for new epidemics. Philos Trans R Soc Lond B Biol Sci. 2017;372(1721):20160297. https://doi.org/10.1098/rstb.2016.0297 PMID: 28396469
-
Moon S, Sridhar D, Pate MA, Jha AK, Clinton C, Delaunay S, et al. Will Ebola change the game? Ten essential reforms before the next pandemic. The report of the Harvard-LSHTM Independent Panel on the Global Response to Ebola. Lancet. 2015;386(10009):2204-21. https://doi.org/10.1016/S0140-6736(15)00946-0 PMID: 26615326
-
Barry A, Ahuka-Mundeke S, Ali Ahmed Y, Allarangar Y, Anoko J, Archer BN, et al. Outbreak of Ebola virus disease in the Democratic Republic of the Congo, April-May, 2018: an epidemiological study. Lancet. 2018;392(10143):213-21. https://doi.org/10.1016/S0140-6736(18)31387-4 PMID: 30047375
-
Ilunga Kalenga O, Moeti M, Sparrow A, Nguyen VK, Lucey D, Ghebreyesus TA. The ongoing Ebola epidemic in the Democratic Republic of Congo, 2018-2019. N Engl J Med. 2019;381(4):373-83. https://doi.org/10.1056/NEJMsr1904253 PMID: 31141654
-
Regules JA, Beigel JH, Paolino KM, Voell J, Castellano AR, Hu Z, et al. A recombinant vesicular stomatitis virus Ebola vaccine. N Engl J Med. 2017;376(4):330-41. https://doi.org/10.1056/NEJMoa1414216 PMID: 25830322
-
World Health Organization (WHO). Surveillance System of Attacks on Healthcare (SSA). Geneva: WHO; 2019. Available from: https://www.who.int/emergencies/attacks-on-health-care/surveillance-system/en/
-
World Health Organization (WHO). Dead and injured following attacks on Ebola responders in the Democratic Republic of the Congo. Geneva: WHO; 2019. Available from: https://www.who.int/news-room/detail/28-11-2019-dead-and-injured-following-attacks-on-ebola-responders-in-the-democratic-republic-of-the-congo
-
Wannier SR, Worden L, Hoff NA, Amezcua E, Selo B, Sinai C, et al. Estimating the impact of violent events on transmission in Ebola virus disease outbreak, Democratic Republic of the Congo, 2018-2019. Epidemics. 2019;28:100353. https://doi.org/10.1016/j.epidem.2019.100353 PMID: 31378584
-
Wells CR, Pandey A, Ndeffo Mbah ML, Gaüzère BA, Malvy D, Singer BH, et al. The exacerbation of Ebola outbreaks by conflict in the Democratic Republic of the Congo. Proc Natl Acad Sci USA. 2019;116(48):24366-72. https://doi.org/10.1073/pnas.1913980116 PMID: 31636188
-
Kamvar ZN, Cai J, Pulliam JRC, Schumacher J, Jombart T. Epidemic curves made easy using the R package incidence. F1000 Res. 2019;8:139. https://doi.org/10.12688/f1000research.18002.1 PMID: 31119031
-
Wallinga J, Lipsitch M. How generation intervals shape the relationship between growth rates and reproductive numbers. Proc Biol Sci. 2007;274(1609):599-604. https://doi.org/10.1098/rspb.2006.3754 PMID: 17476782
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