1887
  1. Home
  2. Eurosurveillance
  3. Volume 25, Issue 18, 07/May/2020
  4. Article
Rapid communication Open Access
Like 0
Download

Abstract

Data on features of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children and adolescents are scarce. We report preliminary results of an Italian multicentre study comprising 168 laboratory-confirmed paediatric cases (median: 2.3 years, range: 1 day–17.7 years, 55.9% males), of which 67.9% were hospitalised and 19.6% had comorbidities. Fever was the most common symptom, gastrointestinal manifestations were frequent; two children required intensive care, five had seizures, 49 received experimental treatments and all recovered.

© Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Closure
A corrected article has been published for this content:
Authors’ correction for Euro Surveill. 2020;25(18)
Loading

Article metrics loading...

/content/10.2807/1560-7917.ES.2020.25.18.2000600
2020-05-07
2024-12-30
/content/10.2807/1560-7917.ES.2020.25.18.2000600
Loading
Loading full text...

Full text loading...

/deliver/fulltext/eurosurveillance/25/18/eurosurv-25-18-1.html?itemId=/content/10.2807/1560-7917.ES.2020.25.18.2000600&mimeType=html&fmt=ahah

References

  1. Bialek S, Gierke R, Hughes M, McNamara LA, Pilishvili T, Skoff T, CDC COVID-19 Response Team. Coronavirus disease 2019 in children - United States, February 12-April 2, 2020. MMWR Morb Mortal Wkly Rep. 2020;69(14):422-6.  https://doi.org/10.15585/mmwr.mm6914e4  PMID: 32271728 
  2. Lu X, Zhang L, Du H, Zhang J, Li YY, Qu J, et al. SARS-CoV-2 Infection in Children. N Engl J Med. 2020;382(17):1663-5.  https://doi.org/10.1056/NEJMc2005073  PMID: 32187458 
  3. European Centre for Disease Prevention and Control (ECDC). Rapid risk assessment. Coronavirus disease 2019 (COVID-19) in the EU/EEA and the UK – eighth update. Stockholm: ECDC; 2020. Available from: https://www.ecdc.europa.eu/sites/default/files/documents/covid-19-rapid-risk-assessment-coronavirus-disease-2019-eighth-update-8-april-2020.pdf
  4. Epicentro, Istituto Superiore di Sanità (ISS). Epidemia COVID-19. Aggiornamento nazionale 9 aprile 2020 – ore 16:00. [COVID-19 epidemic. 9 April 2020 national update – 4 pm]. Rome: ISS; 10 April 2020. Italian. Available from: https://www.epicentro.iss.it/coronavirus/bollettino/Bollettino-sorveglianza-integrata-COVID-19_9-aprile-2020.pdf
  5. Onder G, Rezza G, Brusaferro S. Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy. JAMA. 2020.  https://doi.org/10.1001/jama.2020.4683  PMID: 32203977 
  6. Lee PI, Hu YL, Chen PY, Huang YC, Hsueh PR. Are children less susceptible to COVID-19? J Microbiol Immunol Infect. 2020. PMID: 32147409 
  7. Italian Ministry of Health. Rapporto annuale sull’attività di ricovero ospedaliero (DATI SDO 2018). [Annual report on hospitalization activity. Hospital discharge records data 2018]. Rome: Italian Ministry of Health; 2020. Italian. Available from: http://www.salute.gov.it/portale/documentazione/p6_2_2_1.jsp?lingua=italiano&id=2898
  8. Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z, et al. Epidemiology of COVID-19 among children in China. Pediatrics. 2020; e20200702.  https://doi.org/10.1542/peds.2020-0702  PMID: 32179660 
  9. Qiu H, Wu J, Hong L, Luo Y, Song Q, Chen D. Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study. Lancet Infect Dis. 2020.  https://doi.org/10.1016/S1473-3099(20)30198-5  PMID: 32220650 
  10. She J, Liu L, Liu W. COVID-19 epidemic: Disease characteristics in children. J Med Virol. 2020.  https://doi.org/10.1002/jmv.25807  PMID: 32232980 
  11. Ludvigsson JF. Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults. Acta Paediatr. 2020.  https://doi.org/10.1111/apa.15270  PMID: 32202343 
Multicentre Italian study of SARS-CoV-2 infection in children and adolescents, preliminary data as at 10 April 2020
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Silvia+Garazzino&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Garazzino Silvia</a>, <a href="/search?value1=Carlotta+Montagnani&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Montagnani Carlotta</a>, <a href="/search?value1=Daniele+Don%C3%A0&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Donà Daniele</a>, <a href="/search?value1=Antonella+Meini&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Meini Antonella</a>, <a href="/search?value1=Enrico+Felici&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Felici Enrico</a>, <a href="/search?value1=Gianluca+Vergine&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Vergine Gianluca</a>, <a href="/search?value1=Stefania+Bernardi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bernardi Stefania</a>, <a href="/search?value1=Roberta+Giacchero&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Giacchero Roberta</a>, <a href="/search?value1=Andrea+Lo+Vecchio&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lo Vecchio Andrea</a>, <a href="/search?value1=Paola+Marchisio&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Marchisio Paola</a>, <a href="/search?value1=Giangiacomo+Nicolini&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nicolini Giangiacomo</a>, <a href="/search?value1=Luca+Pierantoni&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pierantoni Luca</a>, <a href="/search?value1=Ivana+Rabbone&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rabbone Ivana</a>, <a href="/search?value1=Giuseppe+Banderali&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Banderali Giuseppe</a>, <a href="/search?value1=Marco+Denina&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Denina Marco</a>, <a href="/search?value1=Elisabetta+Venturini&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Venturini Elisabetta</a>, <a href="/search?value1=Andrzej+Krzysztofiak&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Krzysztofiak Andrzej</a>, <a href="/search?value1=Raffaele+Badolato&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Badolato Raffaele</a>, <a href="/search?value1=Sonia+Bianchini&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bianchini Sonia</a>, <a href="/search?value1=Luisa+Galli&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Galli Luisa</a>, <a href="/search?value1=Alberto+Villani&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Villani Alberto</a>, <a href="/search?value1=Guido+Castelli-Gattinara&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Castelli-Gattinara Guido</a>, <a href="/search?value1=the+Italian+SITIP-SIP+Pediatric+Infection+Study+Group&option1=author&noRedirect=true" class="nonDisambigAuthorLink">the Italian SITIP-SIP Pediatric Infection Study Group</a></span>. Multicentre Italian study of SARS-CoV-2 infection in children and adolescents, preliminary data as at 10 April 2020. <a href="/content/ecdc">Euro Surveill.</a> 2020;25(18):pii=2000600. <a href="https://doi.org/10.2807/1560-7917.ES.2020.25.18.2000600" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2020.25.18.2000600</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 11 Apr 2020;&nbsp;&nbsp; <span class="generated">Accepted</span>: 07 May 2020 </span> </p>
/content/10.2807/1560-7917.ES.2020.25.18.2000600
/content/10.2807/1560-7917.ES.2020.25.18.2000600
Loading

Data & Media loading...

Submit comment
Close
Comment moderation successfully completed
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error