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Coronavirus disease (COVID-19) in a paucisymptomatic patient: epidemiological and clinical challenge in settings with limited community transmission, Italy, February 2020
- Emanuele Nicastri1,2 , Alessandra D’Abramo1,2 , Giovanni Faggioni3 , Riccardo De Santis3 , Andrea Mariano1 , Luciana Lepore1 , Filippo Molinari3 , Giancarlo Petralito3 , Silvia Fillo3 , Diego Munzi3 , Angela Corpolongo1 , Licia Bordi1 , Fabrizio Carletti1 , Concetta Castiletti1 , Francesca Colavita1 , Eleonora Lalle1 , Nazario Bevilacqua1 , Maria Letizia Giancola1 , Laura Scorzolini1 , Simone Lanini1 , Claudia Palazzolo1 , Angelo De Domenico4 , Maria Anna Spinelli3 , Paola Scognamiglio1 , Paolo Piredda4 , Raffaele Iacomino4 , Andrea Mone4 , Vincenzo Puro1 , Nicola Petrosillo1 , Antonio Battistini5 , Francesco Vairo1 , Florigio Lista3,6 , Giuseppe Ippolito1,6 , on behalf of INMI and the Italian Army COVID-19 study groups7
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View Affiliations Hide AffiliationsAffiliations: 1 National Institute for Infectious Diseases ‘Lazzaro Spallanzani’ IRCCS, Rome, Italy 2 These authors contributed equally to this article and share first authorship 3 Scientific Department, Italian Army Medical Center, Rome, Italy 4 Clinical Sciences Department, Italian Army Medical Center, Rome, Italy 5 Italian Army Surgeon General Office, Rome, Italy 6 These authors contributed equally to this article and share last authorship 7 The members of these groups are acknowledged at the end of the articleLuciana Leporeluciana.lepore inmi.it
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Citation style for this article: Nicastri Emanuele, D’Abramo Alessandra, Faggioni Giovanni, De Santis Riccardo, Mariano Andrea, Lepore Luciana, Molinari Filippo, Petralito Giancarlo, Fillo Silvia, Munzi Diego, Corpolongo Angela, Bordi Licia, Carletti Fabrizio, Castiletti Concetta, Colavita Francesca, Lalle Eleonora, Bevilacqua Nazario, Giancola Maria Letizia, Scorzolini Laura, Lanini Simone, Palazzolo Claudia, De Domenico Angelo, Spinelli Maria Anna, Scognamiglio Paola, Piredda Paolo, Iacomino Raffaele, Mone Andrea, Puro Vincenzo, Petrosillo Nicola, Battistini Antonio, Vairo Francesco, Lista Florigio, Ippolito Giuseppe, on behalf of INMI and the Italian Army COVID-19 study groups. Coronavirus disease (COVID-19) in a paucisymptomatic patient: epidemiological and clinical challenge in settings with limited community transmission, Italy, February 2020. Euro Surveill. 2020;25(11):pii=2000230. https://doi.org/10.2807/1560-7917.ES.2020.25.11.2000230 Received: 03 Mar 2020; Accepted: 18 Mar 2020
Abstract
Data concerning the transmission of the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) in paucisymptomatic patients are lacking. We report an Italian paucisymptomatic case of coronavirus disease 2019 with multiple biological samples positive for SARS-CoV-2. This case was detected using the World Health Organization protocol on cases and contact investigation. Current discharge criteria and the impact of extra-pulmonary SARS-CoV-2 samples are discussed.
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