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- Volume 25, Issue 11, 19/Mar/2020
Eurosurveillance - Volume 25, Issue 11, 19 March 2020
Volume 25, Issue 11, 2020
- E-alert
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Rapidly increasing cumulative incidence of coronavirus disease (COVID-19) in the European Union/European Economic Area and the United Kingdom, 1 January to 15 March 2020
The cumulative incidence of coronavirus disease (COVID-19) cases is showing similar trends in European Union/European Economic Area countries and the United Kingdom confirming that, while at a different stage depending on the country, the COVID-19 pandemic is progressing rapidly in all countries. Based on the experience from Italy, countries, hospitals and intensive care units should increase their preparedness for a surge of patients with COVID-19 who will require healthcare, and in particular intensive care.
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- Rapid communication
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Influenza-associated pneumonia as reference to assess seriousness of coronavirus disease (COVID-19)
Information on severity of coronavirus disease (COVID-19) (transmissibility, disease seriousness, impact) is crucial for preparation of healthcare sectors. We present a simple approach to assess disease seriousness, creating a reference cohort of pneumonia patients from sentinel hospitals. First comparisons exposed a higher rate of COVID-19 patients requiring ventilation. There were more case fatalities among COVID-19 patients without comorbidities than in the reference cohort. Hospitals should prepare for high utilisation of ventilation and intensive care resources.
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Coronavirus disease (COVID-19) in a paucisymptomatic patient: epidemiological and clinical challenge in settings with limited community transmission, Italy, February 2020
Emanuele Nicastri , Alessandra D’Abramo , Giovanni Faggioni , Riccardo De Santis , Andrea Mariano , Luciana Lepore , Filippo Molinari , Giancarlo Petralito , Silvia Fillo , Diego Munzi , Angela Corpolongo , Licia Bordi , Fabrizio Carletti , Concetta Castiletti , Francesca Colavita , Eleonora Lalle , Nazario Bevilacqua , Maria Letizia Giancola , Laura Scorzolini , Simone Lanini , Claudia Palazzolo , Angelo De Domenico , Maria Anna Spinelli , Paola Scognamiglio , Paolo Piredda , Raffaele Iacomino , Andrea Mone , Vincenzo Puro , Nicola Petrosillo , Antonio Battistini , Francesco Vairo , Florigio Lista , Giuseppe Ippolito and on behalf of INMI and the Italian Army COVID-19 study groupsData concerning the transmission of the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) in paucisymptomatic patients are lacking. We report an Italian paucisymptomatic case of coronavirus disease 2019 with multiple biological samples positive for SARS-CoV-2. This case was detected using the World Health Organization protocol on cases and contact investigation. Current discharge criteria and the impact of extra-pulmonary SARS-CoV-2 samples are discussed.
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Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020
Anu Haveri , Teemu Smura , Suvi Kuivanen , Pamela Österlund , Jussi Hepojoki , Niina Ikonen , Marjaana Pitkäpaasi , Soile Blomqvist , Esa Rönkkö , Anu Kantele , Tomas Strandin , Hannimari Kallio-Kokko , Laura Mannonen , Maija Lappalainen , Markku Broas , Miao Jiang , Lotta Siira , Mika Salminen , Taneli Puumalainen , Jussi Sane , Merit Melin , Olli Vapalahti and Carita Savolainen-KopraThe first case of coronavirus disease (COVID-19) in Finland was confirmed on 29 January 2020. No secondary cases were detected. We describe the clinical picture and laboratory findings 3–23 days since the first symptoms. The SARS-CoV-2/Finland/1/2020 virus strain was isolated, the genome showing a single nucleotide substitution to the reference strain from Wuhan. Neutralising antibody response appeared within 9 days along with specific IgM and IgG response, targeting particularly nucleocapsid and spike proteins.
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Outbreak of pneumococcal pneumonia among shipyard workers in Marseille, France, January to February 2020
Nadim Cassir , Laurence Pascal , David Ferrieux , Christiane Bruel , Christophe Guervilly , Stanislas Rebaudet , Kostas Danis , Lora Kopec , Florence Fenollar , Emmanuelle Varon , Véronique Vig , Jean-Luc Lasalle , Lauriane Ramalli , Pierre Michelet , Jean-Christophe Lagier , Nicolas Persico , Philippe Brouqui , Philippe Malfait and Philippe ParolaWe report the third outbreak of pneumococcal pneumonia within one year among workers in European shipyards. During January and February 2020, 37 cases of pneumonia were identified in a shipyard in Marseille, south-eastern France. Outbreak control measures were implemented, including a mass vaccination campaign with 23-valent pneumococcal polysaccharide vaccine targeting all shipyard workers. Given the high mobility of shipyard workers, coordinated responses between European public health institutes are necessary to avoid further outbreaks.
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- Surveillance
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The changing epidemiology of diphtheria in the United Kingdom, 2009 to 2017
BackgroundDiphtheria is a potentially fatal disease caused by toxigenic strains of Corynebacterium diphtheriae, C. ulcerans or C. pseudotuberculosis.
AimOur objective was to review the epidemiology of diphtheria in the United Kingdom (UK) and the impact of recent changes in public health management and surveillance.
MethodsPutative human toxigenic diphtheria isolates in the UK are sent for species confirmation and toxigenicity testing to the National Reference Laboratory. Clinical, epidemiological and microbiological information for toxigenic cases between 2009 and 2017 are described in this population-based prospective surveillance study.
ResultsThere were 33 toxigenic cases of diphtheria aged 4 to 82 years. Causative species were C. diphtheriae (n = 18) and C. ulcerans (n = 15). Most C. diphtheriae cases were cutaneous (14/18) while more than half of C. ulcerans cases had respiratory presentations (8/15). Two thirds (23/33) of cases were inadequately immunised. Two cases with C. ulcerans infections died, both inadequately immunised. The major risk factor for C. diphtheriae aquisition was travel to an endemic area and for C. ulcerans, contact with a companion animal. Most confirmed C. diphtheriae or C. ulcerans isolates (441/507; 87%) submitted for toxigenicity testing were non-toxigenic, however, toxin positivity rates were higher (15/23) for C. ulcerans than C. diphtheriae (18/469). Ten non-toxigenic toxin gene-bearing (NTTB) C. diphtheriae were also detected.
ConclusionDiphtheria is a rare disease in the UK. In the last decade, milder cutaneous C. diphtheriae cases have become more frequent. Incomplete vaccination status was strongly associated with the risk of hospitalisation and death.
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Volumes & issues
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Volume 29 (2024)
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Volume 28 (2023)
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Volume 27 (2022)
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Volume 26 (2021)
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Volume 25 (2020)
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Volume 24 (2019)
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Volume 23 (2018)
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Volume 22 (2017)
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Volume 21 (2016)
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Volume 20 (2015)
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Volume 19 (2014)
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Volume 18 (2013)
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Volume 17 (2012)
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Volume 16 (2011)
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Volume 15 (2010)
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Volume 14 (2009)
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Volume 13 (2008)
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Volume 12 (2007)
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Volume 11 (2006)
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Volume 10 (2005)
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Volume 9 (2004)
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Volume 8 (2003)
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Volume 7 (2002)
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Volume 6 (2001)
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Volume 5 (2000)
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Volume 4 (1999)
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Volume 3 (1998)
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Volume 2 (1997)
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Volume 1 (1996)
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Volume 0 (1995)
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Victor M Corman , Olfert Landt , Marco Kaiser , Richard Molenkamp , Adam Meijer , Daniel KW Chu , Tobias Bleicker , Sebastian Brünink , Julia Schneider , Marie Luisa Schmidt , Daphne GJC Mulders , Bart L Haagmans , Bas van der Veer , Sharon van den Brink , Lisa Wijsman , Gabriel Goderski , Jean-Louis Romette , Joanna Ellis , Maria Zambon , Malik Peiris , Herman Goossens , Chantal Reusken , Marion PG Koopmans and Christian Drosten
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