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Abstract

We describe a ceftriaxone-resistant Typhi bacteraemia in a pregnant woman returning from a family visit in Pakistan. Whole genome sequencing confirmed similarity to a Pakistani outbreak clone. Pregnancy and unawareness of this outbreak delayed appropriate antibiotic therapy. Concurrently, we detected faecal carriage of a carbapenemase-producing Awareness of the ongoing outbreak should affect empiric treatment of typhoid fever and hygiene precautions in travellers returning from Pakistan. Meropenem may be warranted in severe cases.

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/content/10.2807/1560-7917.ES.2019.24.21.1900289
2019-05-23
2025-02-22
/content/10.2807/1560-7917.ES.2019.24.21.1900289
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Ceftriaxone-resistant Salmonella enterica serotype Typhi in a pregnant traveller returning from Karachi, Pakistan to Denmark, 2019
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Anne+Line+Engsbro&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Engsbro Anne Line</a>, <a href="/search?value1=Hans+S%C3%B8e+Riis+Jespersen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Riis Jespersen Hans Søe</a>, <a href="/search?value1=Maria+Ingeborg+Goldschmidt&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Goldschmidt Maria Ingeborg</a>, <a href="/search?value1=Sarah+Mollerup&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mollerup Sarah</a>, <a href="/search?value1=Peder+Worning&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Worning Peder</a>, <a href="/search?value1=Martin+Schou+Pedersen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pedersen Martin Schou</a>, <a href="/search?value1=Henrik+Westh&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Westh Henrik</a>, <a href="/search?value1=Uffe+Vest+Schneider&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Schneider Uffe Vest</a></span>. Ceftriaxone-resistant Salmonella enterica serotype Typhi in a pregnant traveller returning from Karachi, Pakistan to Denmark, 2019. <a href="/content/ecdc">Euro Surveill.</a> 2019;24(21):pii=1900289. <a href="https://doi.org/10.2807/1560-7917.ES.2019.24.21.1900289" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2019.24.21.1900289</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 13 May 2019;&nbsp;&nbsp; <span class="generated">Accepted</span>: 22 May 2019 </span> </p>
/content/10.2807/1560-7917.ES.2019.24.21.1900289
/content/10.2807/1560-7917.ES.2019.24.21.1900289
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