The re-emergence of highly pathogenic avian influenza H7N9 viruses in humans in mainland China, 2019

Deshan Yu; Guofeng Xiang; Wenfei Zhu; Xia Lei; Baodi Li; Yao Meng; Lei Yang; Hongyan Jiao; Xiyan Li; Weijuan Huang; Hejiang Wei; Yanping Zhang; Yan Hai; Hui Zhang; Hua Yue; Shumei Zou; Xiang Zhao; Chao Li; Deng Ao; Ye Zhang; Minju Tan; Jia Liu; Xuemei Zhang; George F. Gao; Lei Meng; Dayan Wang

doi:10.2807/1560-7917.ES.2019.24.21.1900273

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The re-emergence of highly pathogenic avian influenza H7N9 viruses in humans in mainland China, 2019
Deshan Yu^1,2 , Guofeng Xiang^1,3 , Wenfei Zhu^1,4 , Xia Lei^1,5 , Baodi Li² , Yao Meng⁴ , Lei Yang⁴ , Hongyan Jiao⁶ , Xiyan Li⁴ , Weijuan Huang⁴ , Hejiang Wei⁴ , Yanping Zhang⁷ , Yan Hai⁵ , Hui Zhang² , Hua Yue⁵ , Shumei Zou⁴ , Xiang Zhao⁴ , Chao Li⁷ , Deng Ao⁶ , Ye Zhang⁴ , Minju Tan⁴ , Jia Liu⁴ , Xuemei Zhang⁶ , George F. Gao^4,7 , Lei Meng^2,8 , Dayan Wang^4,8
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Affiliations: ¹ These authors contributed equally in this study as first authors ² Gansu Provincial Center for Disease Control and Prevention, Lanzhou China ³ Jiuquan Center for Disease Control and Prevention, Jiuquan, China ⁴ National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention; WHO Collaborating Center for Reference and Research on Influenza; Key Laboratory for Medical Virology, National Health Commission, Beijing, China ⁵ Inner Mongolia Center for Disease Control and Prevention, Hohehot, China ⁶ Alasan League Center for Disease Control and Prevention, Alasan, China ⁷ Chinese Center for Disease Control and Prevention, Beijing, China ⁸ These authors contributed equally as last authors in this study

Correspondence:
Dayan Wang
dayanwang cnic.org.cn
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Citation style for this article: Yu Deshan, Xiang Guofeng, Zhu Wenfei, Lei Xia, Li Baodi, Meng Yao, Yang Lei, Jiao Hongyan, Li Xiyan, Huang Weijuan, Wei Hejiang, Zhang Yanping, Hai Yan, Zhang Hui, Yue Hua, Zou Shumei, Zhao Xiang, Li Chao, Ao Deng, Zhang Ye, Tan Minju, Liu Jia, Zhang Xuemei, Gao George F., Meng Lei, Wang Dayan. The re-emergence of highly pathogenic avian influenza H7N9 viruses in humans in mainland China, 2019. Euro Surveill. 2019;24(21):pii=1900273. https://doi.org/10.2807/1560-7917.ES.2019.24.21.1900273 Received: 06 May 2019; Accepted: 23 May 2019

Abstract

After no reported human cases of highly pathogenic avian influenza (HPAI) H7N9 for over a year, a case with severe disease occurred in late March 2019. Among HPAI H7N9 viral sequences, those recovered from the case and from environmental samples of a poultry slaughtering stall near their home formed a distinct clade from 2017 viral sequences. Several mutations possibly associated to antigenic drift occurred in the haemagglutinin gene, potentially warranting update of H7N9 vaccine strains.

This work is licensed under a Creative Commons Attribution 4.0 International License.

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2019-05-23

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The re-emergence of highly pathogenic avian influenza H7N9 viruses in humans in mainland China, 2019

Citation style for this article: <a href="/search?value1=Deshan+Yu&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Yu Deshan</a>, <a href="/search?value1=Guofeng+Xiang&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Xiang Guofeng</a>, <a href="/search?value1=Wenfei+Zhu&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Zhu Wenfei</a>, <a href="/search?value1=Xia+Lei&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lei Xia</a>, <a href="/search?value1=Baodi+Li&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Li Baodi</a>, <a href="/search?value1=Yao+Meng&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Meng Yao</a>, <a href="/search?value1=Lei+Yang&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Yang Lei</a>, <a href="/search?value1=Hongyan+Jiao&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Jiao Hongyan</a>, <a href="/search?value1=Xiyan+Li&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Li Xiyan</a>, <a href="/search?value1=Weijuan+Huang&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Huang Weijuan</a>, <a href="/search?value1=Hejiang+Wei&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Wei Hejiang</a>, <a href="/search?value1=Yanping+Zhang&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Zhang Yanping</a>, <a href="/search?value1=Yan+Hai&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hai Yan</a>, <a href="/search?value1=Hui+Zhang&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Zhang Hui</a>, <a href="/search?value1=Hua+Yue&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Yue Hua</a>, <a href="/search?value1=Shumei+Zou&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Zou Shumei</a>, <a href="/search?value1=Xiang+Zhao&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Zhao Xiang</a>, <a href="/search?value1=Chao+Li&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Li Chao</a>, <a href="/search?value1=Deng+Ao&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ao Deng</a>, <a href="/search?value1=Ye+Zhang&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Zhang Ye</a>, <a href="/search?value1=Minju+Tan&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Tan Minju</a>, <a href="/search?value1=Jia+Liu&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Liu Jia</a>, <a href="/search?value1=Xuemei+Zhang&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Zhang Xuemei</a>, <a href="/search?value1=George+F.+Gao&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gao George F.</a>, <a href="/search?value1=Lei+Meng&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Meng Lei</a>, <a href="/search?value1=Dayan+Wang&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Wang Dayan</a>. The re-emergence of highly pathogenic avian influenza H7N9 viruses in humans in mainland China, 2019. <a href="/content/ecdc">Euro Surveill.</a> 2019;24(21):pii=1900273. <a href="https://doi.org/10.2807/1560-7917.ES.2019.24.21.1900273" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2019.24.21.1900273</a> Received: 06 May 2019;   Accepted: 23 May 2019

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The re-emergence of highly pathogenic avian influenza H7N9 viruses in humans in mainland China, 2019

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