Early estimates of seasonal influenza vaccine effectiveness in Europe among target groups for vaccination: results from the I-MOVE multicentre case–control study, 2011/12

E Kissling; M Valenciano; Collective I-MOVE case–control studies team

doi:10.2807/ese.17.15.20146-en

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Early estimates of seasonal influenza vaccine effectiveness in Europe among target groups for vaccination: results from the I-MOVE multicentre case–control study, 2011/12
E Kissling¹ , M Valenciano¹ , Collective I-MOVE case–control studies team²
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Affiliations: ¹ EpiConcept, Paris, France ² Members of the team are listed at the end of the article

Correspondence:
E Kissling
e.kissling epiconcept.fr
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Citation style for this article: Kissling E, Valenciano M, I-MOVE case–control studies team Collective. Early estimates of seasonal influenza vaccine effectiveness in Europe among target groups for vaccination: results from the I-MOVE multicentre case–control study, 2011/12. Euro Surveill. 2012;17(15):pii=20146. https://doi.org/10.2807/ese.17.15.20146-en Received: 03 Apr 2012

Abstract

To provide an early estimate of 2011/12 influenza vaccine effectiveness (VE), we conducted a multicentre case-control study based on seven sentinel surveillance networks. We included influenza-like illness cases up to week 7/2012 from the vaccination target groups, swabbed less than eight days after symptom onset. Laboratory-confirmed influenza A(H3) cases were compared to negative controls. Adjusted VE was 43% (95% confidence interval: -0.4 to 67.7), suggesting low to moderate VE against influenza A(H3) in the early 2011/12 season.