Early estimates of the effectiveness of the 2011/12 influenza vaccine in the population targeted for vaccination in Spain, 25 December 2011 to 19 February 2012

S Jiménez-Jorge; S de Mateo; F Pozo; I Casas; M García Cenoz; J Castilla; V Gallardo; E Pérez; T Vega; C Rodriguez; C Quiñones; E Martínez; J Giménez; J M Vanrell; D Castrillejo; M C Serrano; J M Ramos; A Larrauri

doi:10.2807/ese.17.12.20129-en

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Early estimates of the effectiveness of the 2011/12 influenza vaccine in the population targeted for vaccination in Spain, 25 December 2011 to 19 February 2012
S Jiménez-Jorge^1,2 , S de Mateo^1,2 , F Pozo³ , I Casas³ , M García Cenoz^2,4 , J Castilla^2,4 , V Gallardo⁵ , E Pérez⁵ , T Vega⁶ , C Rodriguez⁶ , C Quiñones⁷ , E Martínez⁷ , J Giménez⁸ , J M Vanrell⁸ , D Castrillejo⁹ , M C Serrano¹⁰ , J M Ramos¹⁰ , A Larrauri^1,2
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Affiliations: ¹ National Centre of Epidemiology, Institute of Health Carlos III, Madrid, Spain ² Ciber Epidemiología y Salud Pública (CIBERESP), Ministry of Economy and Competitiveness, Institute of Health Carlos III, Madrid, Spain ³ National Centre for Microbiology, World Health Organization National Influenza Centre, Institute of Health Carlos III, Madrid, Spain ⁴ Instituto de Salud Pública de Navarra, Navarra, Spain ⁵ Servicio de Epidemiología y Salud Laboral. Secretaría General de Salud Pública y Participación. Consejería de Salud de Andalucía, Seville, Spain ⁶ Dirección General de Salud Pública, Consejería de Sanidad de Castilla y León, Valladolid, Spain ⁷ Servicio de Epidemiología, Subdirección de Salud Pública de La Rioja, La Rioja, Spain ⁸ Servicio de Epidemiología, Dirección General de Salut Pública, Mallorca, Baleares, Spain ⁹ Servicio de Epidemiología, Dirección General de Sanidad y Consumo, Consejería de Bienestar Social y Sanidad, Ciudad Autónoma de Melilla, Spain ¹⁰ Dirección General de Salud Pública, Servicio Extremeño de Salud, Badajoz, Junta de Extremadura, Spain

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S Jiménez-Jorge
sjimenezj isciii.es
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Citation style for this article: Jiménez-Jorge S, de Mateo S, Pozo F, Casas I, García Cenoz M, Castilla J, Gallardo V, Pérez E, Vega T, Rodriguez C, Quiñones C, Martínez E, Giménez J, Vanrell J M, Castrillejo D, Serrano M C, Ramos J M, Larrauri A. Early estimates of the effectiveness of the 2011/12 influenza vaccine in the population targeted for vaccination in Spain, 25 December 2011 to 19 February 2012. Euro Surveill. 2012;17(12):pii=20129. https://doi.org/10.2807/ese.17.12.20129-en Received: 06 Mar 2012

Abstract

We present early estimates of influenza vaccine effectiveness (VE) in the population targeted for vaccination, during 25 December 2011 to 19 February 2012. The adjusted VE was 55% (95% CI: 3 to 79) against any type of influenza virus and 54% (95% CI: 1 to 79) against influenza A(H3N2) virus. This suggests a moderate protective effect of the vaccine in the targeted population in a late influenza epidemic with limited match between vaccine and circulating strains.