Household transmission of haemolytic uraemic syndrome associated with Escherichia coli O104:H4 in the Netherlands, May 2011

E J Kuijper; D Soonawala; C Vermont; J T van Dissel

doi:10.2807/ese.16.25.19897-en

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Household transmission of haemolytic uraemic syndrome associated with Escherichia coli O104:H4 in the Netherlands, May 2011
E J Kuijper¹ , D Soonawala² , C Vermont³ , J T van Dissel⁴
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Affiliations: ¹ Department Medical Microbiology, Centre for Infectious Diseases, Leiden University Medical Centre, Leiden, the Netherlands ² Department of Nefrology, Leiden University Medical Centre, Leiden, the Netherlands ³ Department of Paediatrics, Leiden University Medical Centre, Leiden, the Netherlands ⁴ Department of Infectious Disease, Centre for Infectious Diseases, Leiden University Medical Centre, Leiden, the Netherlands

Correspondence:
E Kuijper
e.j.kuijper lumc.nl
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Citation style for this article: Kuijper E J, Soonawala D, Vermont C, van Dissel J T. Household transmission of haemolytic uraemic syndrome associated with Escherichia coli O104:H4 in the Netherlands, May 2011. Euro Surveill. 2011;16(25):pii=19897. https://doi.org/10.2807/ese.16.25.19897-en Received: 22 Jun 2011

Abstract

Following the outbreak of haemolytic uraemic syndrome (HUS) and haemorrhagic colitis in Germany, two patients returning from a stay in Germany developed HUS due to Escherichia coli O104:H4 in the Netherlands. The index case developed symptoms eight days, and her child 15 days after their return. It is very likely that transmission resulted from secondary spread from mother to child. Recommendations should be made to prevent secondary transmission within households.