Association between 2009 seasonal influenza vaccine and influenza-like illness during the 2009 pandemic: preliminary results of a large household transmission study in Western Australia

D Carcione; C Giele; L S Goggin; K S Kwan; D W Smith; G K Dowse; D B Mak; P Effler

doi:10.2807/ese.15.28.19616-en

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Association between 2009 seasonal influenza vaccine and influenza-like illness during the 2009 pandemic: preliminary results of a large household transmission study in Western Australia
D Carcione¹ , C Giele¹ , L S Goggin¹ , K S Kwan¹ , D W Smith² , G K Dowse¹ , D B Mak¹ , P Effler¹
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Affiliations: ¹ Communicable Disease Control Directorate, Department of Health, Perth, Western Australia, Australia ² PathWest Laboratory Medicine WA, Nedlands, Western Australia, Australia

Correspondence:
P Effler
Paul.Effler health.wa.gov.au
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Citation style for this article: Carcione D, Giele C, Goggin L S, Kwan K S, Smith D W, Dowse G K, Mak D B, Effler P. Association between 2009 seasonal influenza vaccine and influenza-like illness during the 2009 pandemic: preliminary results of a large household transmission study in Western Australia. Euro Surveill. 2010;15(28):pii=19616. https://doi.org/10.2807/ese.15.28.19616-en Received: 08 Jul 2010

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Abstract

We conducted a prospective household transmission study to examine whether receipt of 2009 trivalent influenza vaccine (TIV) was associated with increased risk of influenza-like illness (ILI) among contacts of confirmed pandemic influenza A(H1N1) 2009 patients. In the week following onset of pandemic illness in a household member, 46 (15%) of 304 TIV-vaccinated contacts, and 174 (15%) of 1,162 unvaccinated contacts developed ILI (p= 0.95). Receipt of 2009 TIV had no effect on one's risk of pandemic illness. .