Molecular characterisation of PFGE non-typable methicillin-resistant Staphylococcus aureus in the Netherlands, 2007

X W Huijsdens; T Bosch; M G van Santen-Verheuvel; E Spalburg; G N Pluister; M van Luit; M E Heck; A Haenen; A J de Neeling

doi:10.2807/ese.14.38.19335-en

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Molecular characterisation of PFGE non-typable methicillin-resistant Staphylococcus aureus in the Netherlands, 2007
X W Huijsdens¹ , T Bosch¹ , M G van Santen-Verheuvel¹ , E Spalburg¹ , G N Pluister¹ , M van Luit¹ , M E Heck¹ , A Haenen¹ , A J de Neeling¹
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Affiliations: ¹ National Institute for Public Health and the Environment, Bilthoven, The Netherlands

Correspondence:
X Huijsdens
Xander.Huijsdens rivm.nl
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Citation style for this article: Huijsdens X W, Bosch T, van Santen-Verheuvel M G, Spalburg E, Pluister G N, van Luit M, Heck M E, Haenen A, de Neeling A J. Molecular characterisation of PFGE non-typable methicillin-resistant Staphylococcus aureus in the Netherlands, 2007. Euro Surveill. 2009;14(38):pii=19335. https://doi.org/10.2807/ese.14.38.19335-en Received: 20 Feb 2009

Abstract

In 2007 in the Netherlands, 30% of all human isolates of methicillin-resistant Staphylococcus aureus (MRSA) sent to the National Institute for Public Health and the Environment could not be typed by pulsed-field gel electrophoresis (non-typable (NT)-MRSA). Molecular characterisation of the NT-MRSA isolates revealed 27 different spa types and two distinct SCCmec types, type IV and V. All NT-MRSA isolates were closely related based on spa and multi-locus sequence typing and belonged to the ST398 lineage. The rapid increase of NT-MRSA (ST398) isolates over the last years shows the importance of this relatively new clonal lineage.