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Abstract

Antimicrobial agents used to treat infections are life-saving. Overuse may result in more frequent adverse effects and emergence of multidrug-resistant microorganisms. In 2016–17, we performed the second point-prevalence survey (PPS) of healthcare-associated infections (HAIs) and antimicrobial use in European acute care hospitals. We included 1,209 hospitals and 310,755 patients in 28 of 31 European Union/European Economic Area (EU/EEA) countries. The weighted prevalence of antimicrobial use in the EU/EEA was 30.5% (95% CI: 29.2–31.9%). The most common indication for prescribing antimicrobials was treatment of a community-acquired infection, followed by treatment of HAI and surgical prophylaxis. Over half (54.2%) of antimicrobials for surgical prophylaxis were prescribed for more than 1 day. The most common infections treated by antimicrobials were respiratory tract infections and the most commonly prescribed antimicrobial agents were penicillins with beta-lactamase inhibitors. There was wide variation of patients on antimicrobials, in the selection of antimicrobial agents and in antimicrobial stewardship resources and activities across the participating countries. The results of the PPS provide detailed information on antimicrobial use in European acute care hospitals, enable comparisons between countries and hospitals, and highlight key areas for national and European action that will support efforts towards prudent use of antimicrobials.

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/content/10.2807/1560-7917.ES.23.46.1800393
2018-11-15
2024-11-25
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.23.46.1800393
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Antimicrobial use in European acute care hospitals: results from the second point prevalence survey (PPS) of healthcare-associated infections and antimicrobial use, 2016 to 2017
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Diamantis+Plachouras&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Plachouras Diamantis</a>, <a href="/search?value1=Tommi+K%C3%A4rki&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kärki Tommi</a>, <a href="/search?value1=Sonja+Hansen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hansen Sonja</a>, <a href="/search?value1=Susan+Hopkins&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hopkins Susan</a>, <a href="/search?value1=Outi+Lyytik%C3%A4inen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lyytikäinen Outi</a>, <a href="/search?value1=Maria+Luisa+Moro&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Moro Maria Luisa</a>, <a href="/search?value1=Jacqui+Reilly&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Reilly Jacqui</a>, <a href="/search?value1=Peter+Zarb&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Zarb Peter</a>, <a href="/search?value1=Walter+Zingg&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Zingg Walter</a>, <a href="/search?value1=Pete+Kinross&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kinross Pete</a>, <a href="/search?value1=Klaus+Weist&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Weist Klaus</a>, <a href="/search?value1=Dominique+L.+Monnet&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Monnet Dominique L.</a>, <a href="/search?value1=Carl+Suetens&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Suetens Carl</a>, <a href="/search?value1=the+Point+Prevalence+Survey+Study+Group&option1=author&noRedirect=true" class="nonDisambigAuthorLink">the Point Prevalence Survey Study Group</a></span>. Antimicrobial use in European acute care hospitals: results from the second point prevalence survey (PPS) of healthcare-associated infections and antimicrobial use, 2016 to 2017. <a href="/content/ecdc">Euro Surveill.</a> 2018;23(46):pii=1800393. <a href="https://doi.org/10.2807/1560-7917.ES.23.46.1800393" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.23.46.1800393</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 18 Jul 2018;&nbsp;&nbsp; <span class="generated">Accepted</span>: 16 Oct 2018 </span> </p>
/content/10.2807/1560-7917.ES.23.46.1800393
/content/10.2807/1560-7917.ES.23.46.1800393
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