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Detection of circulating vaccine-derived poliovirus type 2 (cVDPV2) in wastewater samples: a wake-up call, Finland, Germany, Poland, Spain, the United Kingdom, 2024
- Sindy Böttcher1 , Julian Kreibich1 , Thomas Wilton2 , Vanessa Saliba3 , Soile Blomqvist4 , Haider Al-Hello4 , Carita Savolainen-Kopra4 , Magdalena Wieczorek5 , Beata Gad5 , Arleta Krzysztoszek5 , Rosa M Pintó6 , María Cabrerizo7 , Albert Bosch6 , Eugene Saxentoff8 , Sabine Diedrich1 , Javier Martin2
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View Affiliations Hide AffiliationsAffiliations: 1 Robert Koch Institute (RKI), Berlin, Germany 2 Medicines and Healthcare products Regulatory Agency (MHRA), South Mimms (Potters Bar), United Kingdom 3 United Kingdom Health Security Agency (UKHSA), London, United Kingdom 4 Finnish Institute for Health and Welfare (THL), Helsinki, Finland 5 National Institute of Public Health NIH – National Institute of Research, Warsaw, Poland 6 University of Barcelona, Barcelona, Spain 7 Instituto de Salud Carlos III (ISCII), Madrid, Spain 8 World Health Organization Regional Office for Europe (WHO/Europe), Copenhagen, DenmarkJavier MartinJavier.Martin mhra.gov.uk
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Citation style for this article: Böttcher Sindy, Kreibich Julian, Wilton Thomas, Saliba Vanessa, Blomqvist Soile, Al-Hello Haider, Savolainen-Kopra Carita, Wieczorek Magdalena, Gad Beata, Krzysztoszek Arleta, Pintó Rosa M, Cabrerizo María, Bosch Albert, Saxentoff Eugene, Diedrich Sabine, Martin Javier. Detection of circulating vaccine-derived poliovirus type 2 (cVDPV2) in wastewater samples: a wake-up call, Finland, Germany, Poland, Spain, the United Kingdom, 2024. Euro Surveill. 2025;30(3):pii=2500037. https://doi.org/10.2807/1560-7917.ES.2025.30.3.2500037 Received: 13 Jan 2025; Accepted: 23 Jan 2025
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Abstract
In 2024, circulating vaccine-derived poliovirus type 2 (cVDPV2) was detected in wastewater samples in Finland, Germany, Poland, Spain and the United Kingdom (UK). All strains were genetically linked, but sequence analysis showed high genetic diversity among the strains identified within individual wastewater sites and countries and an unexpected high genetic proximity among isolates from different countries. Taken together these results, with sequential samples having tested positive in various sites, a broader geographic distribution beyond positive sampling sites must be considered.
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