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Abstract

We report two importations of monkeypox virus clade Ib infection to the United Kingdom in 2024. The first was a traveller returning from Tanzania, Rwanda and Uganda, the second from Uganda. Both presented with fever and typical skin lesions; 147 contacts were followed up, 19 vaccinated with MVA-BN. Three household contacts of the first individual, including two children, became infected. These are the first reported autochthonous transmissions of clade Ib in Europe, and first paediatric cases outside the African continent.

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/content/10.2807/1560-7917.ES.2025.30.10.2500131
2025-03-13
2025-03-17
/content/10.2807/1560-7917.ES.2025.30.10.2500131
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Case series of the first five human infections with monkeypox virus clade Ib and report on the public health response, United Kingdom, October to November 2024
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Muhammad+Ibaad+Alvi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Alvi Muhammad Ibaad</a>, <a href="/search?value1=Merav+Kliner&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kliner Merav</a>, <a href="/search?value1=William+Welfare&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Welfare William</a>, <a href="/search?value1=N+Claire+Gordon&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gordon N Claire</a>, <a href="/search?value1=Sherine+Thomas&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Thomas Sherine</a>, <a href="/search?value1=Simon+Padfield&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Padfield Simon</a>, <a href="/search?value1=Hannah+E+Emmett&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Emmett Hannah E</a>, <a href="/search?value1=Ellen+Heinsbroek&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Heinsbroek Ellen</a>, <a href="/search?value1=Gareth+J+Hughes&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hughes Gareth J</a>, <a href="/search?value1=Natalie+Groves&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Groves Natalie</a>, <a href="/search?value1=Eileen+Gallagher&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gallagher Eileen</a>, <a href="/search?value1=Steven+Pullan&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pullan Steven</a>, <a href="/search?value1=Amy+Belfield&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Belfield Amy</a>, <a href="/search?value1=Catherine+F+Houlihan&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Houlihan Catherine F</a>, <a href="/search?value1=Tommy+Rampling&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rampling Tommy</a>, <a href="/search?value1=Geraldine+O%E2%80%99Hara&option1=author&noRedirect=true" class="nonDisambigAuthorLink">O’Hara Geraldine</a>, <a href="/search?value1=Anne+Tunbridge&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Tunbridge Anne</a>, <a href="/search?value1=Jake+Dunning&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Dunning Jake</a>, <a href="/search?value1=Elizabeth+Whittaker&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Whittaker Elizabeth</a>, <a href="/search?value1=Alejandra+Alonso&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Alonso Alejandra</a>, <a href="/search?value1=Mike+Beadsworth&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Beadsworth Mike</a>, <a href="/search?value1=Brendan+AI+Payne&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Payne Brendan AI</a>, <a href="/search?value1=Meera+Chand&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Chand Meera</a>, <a href="/search?value1=Susan+Hopkins&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hopkins Susan</a>, <a href="/search?value1=Gillian+Armstrong&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Armstrong Gillian</a></span>. Case series of the first five human infections with monkeypox virus clade Ib and report on the public health response, United Kingdom, October to November 2024. <a href="/content/ecdc">Euro Surveill.</a> 2025;30(10):pii=2500131. <a href="https://doi.org/10.2807/1560-7917.ES.2025.30.10.2500131" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2025.30.10.2500131</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 24 Feb 2025;&nbsp;&nbsp; <span class="generated">Accepted</span>: 12 Mar 2025 </span> </p>
/content/10.2807/1560-7917.ES.2025.30.10.2500131
/content/10.2807/1560-7917.ES.2025.30.10.2500131
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