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2023/24 mid-season influenza and Omicron XBB.1.5 vaccine effectiveness estimates from the Canadian Sentinel Practitioner Surveillance Network (SPSN)
- Danuta M Skowronski1,2 , Yuping Zhan1 , Samantha E Kaweski1 , Suzana Sabaiduc1 , Ayisha Khalid1 , Romy Olsha3 , Sara Carazo4 , James A Dickinson5 , Richard G Mather3,6 , Hugues Charest4 , Agatha N Jassem1 , Inès Levade4 , Maan Hasso3 , Nathan Zelyas7 , Ruimin Gao8 , Nathalie Bastien8
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View Affiliations Hide AffiliationsAffiliations: 1 British Columbia Centre for Disease Control, Vancouver, Canada 2 University of British Columbia, Vancouver, Canada 3 Public Health Ontario, Toronto, Canada 4 Institut National de Santé Publique du Québec, Québec, Canada 5 University of Calgary, Calgary, Canada 6 Queen’s University, Kingston, Canada 7 Public Health Laboratory, Alberta Precision Laboratories, Edmonton, Canada 8 National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, CanadaDanuta M SkowronskiDanuta.Skowronski bccdc.ca
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Citation style for this article: Skowronski Danuta M, Zhan Yuping, Kaweski Samantha E, Sabaiduc Suzana, Khalid Ayisha, Olsha Romy, Carazo Sara, Dickinson James A, Mather Richard G, Charest Hugues, Jassem Agatha N, Levade Inès, Hasso Maan, Zelyas Nathan, Gao Ruimin, Bastien Nathalie. 2023/24 mid-season influenza and Omicron XBB.1.5 vaccine effectiveness estimates from the Canadian Sentinel Practitioner Surveillance Network (SPSN). Euro Surveill. 2024;29(7):pii=2400076. https://doi.org/10.2807/1560-7917.ES.2024.29.7.2400076 Received: 03 Feb 2024; Accepted: 14 Feb 2024
Abstract
The Canadian Sentinel Practitioner Surveillance Network reports mid-season 2023/24 influenza vaccine effectiveness (VE) of 63% (95% CI: 51–72) against influenza A(H1N1)pdm09, lower for clade 5a.2a.1 (56%; 95% CI: 33–71) than clade 5a.2a (67%; 95% CI: 48–80), and lowest against influenza A(H3N2) (40%; 95% CI: 5–61). The Omicron XBB.1.5 vaccine protected comparably well, with VE of 47% (95% CI: 21–65) against medically attended COVID-19, higher among people reporting a prior confirmed SARS-CoV-2 infection at 67% (95% CI: 28–85).
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