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Co-circulation of monkeypox virus subclades Ia and Ib in Kinshasa Province, Democratic Republic of the Congo, July to August 2024
- Tony Wawina-Bokalanga1,2,3 , Prince Akil-Bandali1 , Eddy Kinganda-Lusamaki1,2,4 , Emmanuel Lokilo1 , Daan Jansen3 , Adrienne Amuri-Aziza1 , Jean-Claude Makangara-Cigolo1,2,5 , Elisabeth Pukuta-Simbu1 , Rilia Ola-Mpumbe1 , Mamito Muyembe1 , Cris Kacita6 , Princesse Paku-Tshambu1 , Pedro HLF Dantas3 , Olivier Tshiani-Mbaya1,2 , Gradi Luakanda1 , Antoine Nkuba-Ndaye1,2 , Meris Matondo1,2 , Emmanuel Hasivirwe Vakaniaki1,3 , Sofonias Tessema7 , Nicaise Ndembi7 , Áine O’Toole8 , Tessa De Block3 , Christian Ngandu6 , Nicole A Hoff9 , Nicola Low10 , Lorenzo Subissi11 , Sydney Merritt9 , Jean-Jacques Muyembe-Tamfum1,2 , Laurens Liesenborghs3,12 , Martine Peeters4 , Eric Delaporte4 , Jason Kindrachuk13 , Anne W Rimoin9 , Steve Ahuka-Mundeke1,2 , Andrew Rambaut8 , Dieudonné Mwamba6 , Koen Vercauteren3,* , Placide Mbala-Kingebeni1,2,*
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View Affiliations Hide AffiliationsAffiliations: 1 Institut National de Recherche Biomédicale (INRB), Kinshasa, Democratic Republic of the Congo 2 Service de Microbiologie, Département de Biologie Médicale, Cliniques Universitaires de Kinshasa, Université de Kinshasa, Kinshasa, Democratic Republic of the Congo 3 Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium 4 TransVIHMI, Université de Montpellier, INSERM, IRD, Montpellier, France 5 Graduate School of Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland 6 Institut National de Santé Publique (INSP), Kinshasa, Democratic Republic of the Congo 7 Africa Centres for Disease Control and Prevention, Addis Ababa, Ethiopia 8 Institute of Ecology and Evolution, University of Edinburgh, Edinburgh, United Kingdom 9 Department of Epidemiology, Jonathan and Karin Fielding School of Public Health, University of California, Los Angeles, CA, United States 10 Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland 11 World Health Organization, Geneva, Switzerland 12 Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium 13 Department of Medical Microbiology & Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada; Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada * These authors contributed equally to this work and share last authorship.
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Citation style for this article: Wawina-Bokalanga Tony, Akil-Bandali Prince, Kinganda-Lusamaki Eddy, Lokilo Emmanuel, Jansen Daan, Amuri-Aziza Adrienne, Makangara-Cigolo Jean-Claude, Pukuta-Simbu Elisabeth, Ola-Mpumbe Rilia, Muyembe Mamito, Kacita Cris, Paku-Tshambu Princesse, Dantas Pedro HLF, Tshiani-Mbaya Olivier, Luakanda Gradi, Nkuba-Ndaye Antoine, Matondo Meris, Vakaniaki Emmanuel Hasivirwe, Tessema Sofonias, Ndembi Nicaise, O’Toole Áine, De Block Tessa, Ngandu Christian, Hoff Nicole A, Low Nicola, Subissi Lorenzo, Merritt Sydney, Muyembe-Tamfum Jean-Jacques, Liesenborghs Laurens, Peeters Martine, Delaporte Eric, Kindrachuk Jason, Rimoin Anne W, Ahuka-Mundeke Steve, Rambaut Andrew, Mwamba Dieudonné, Vercauteren Koen, Mbala-Kingebeni Placide. Co-circulation of monkeypox virus subclades Ia and Ib in Kinshasa Province, Democratic Republic of the Congo, July to August 2024. Euro Surveill. 2024;29(38):pii=2400592. https://doi.org/10.2807/1560-7917.ES.2024.29.38.2400592 Received: 07 Sept 2024; Accepted: 19 Sept 2024
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Abstract
Between January and August 2024, mpox cases have been reported in nearly all provinces of the Democratic Republic of the Congo (DRC). Monkeypox virus genome sequences were obtained from 11 mpox cases’ samples, collected in July–August 2024 in several health zones of Kinshasa. Characterisation of the sequences showed subclades Ia and Ib co-circulating in the Limete health zone, while phylogenetic analyses suggested multiple introductions of the two subclades in Kinshasa. This illustrates the growing complexity of Clade I mpox outbreaks in DRC.
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