1887
  1. Home
  2. Eurosurveillance
  3. Volume 29, Issue 18, 02/May/2024
  4. Article
Rapid communication Open Access
Like 0
Download

Abstract

In March 2024, the first ever human case of rabies, following a dog bite, was detected in Timor-Leste. This paper briefly discusses the circumstances of transmission, clinical presentation, palliative care of the case and public health measures taken. Timor-Leste was previously considered rabies-free. Any person who is bitten or scratched by an animal that could potentially transmit rabies virus (especially dogs, bats, monkeys or cats) in Timor-Leste should be assessed for consideration of provision of rabies post-exposure prophylaxis.

© Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Loading

Article metrics loading...

/content/10.2807/1560-7917.ES.2024.29.18.2400241
2024-05-02
2025-03-13
/content/10.2807/1560-7917.ES.2024.29.18.2400241
Loading
Loading full text...

Full text loading...

/deliver/fulltext/eurosurveillance/29/18/eurosurv-29-18_1.html?itemId=/content/10.2807/1560-7917.ES.2024.29.18.2400241&mimeType=html&fmt=ahah

References

  1. World Health Organization (WHO). Rabies. Geneva: WHO; 20 Sep 2023. Available from: https://www.who.int/news-room/fact-sheets/detail/rabies/
  2. World Health Organization (WHO). Zero by 30: the global strategic plan to end human deaths from dog-mediated rabies by 2030. Geneva: WHO; 3 Jun 2018. Available from: https://www.who.int/publications/i/item/9789241513838
  3. Franka R. Rabies. In: Heymann DL, editor. Control of Communicable Diseases Manual. Washington: American Public Health Association; 2015, p. 497-508.
  4. Centers for Disease Control and Prevention (CDC). Rabies Post-exposure Prophylaxis (PEP). Atlanta: CDC; 4 May 2022. Available from: https://www.cdc.gov/rabies/medical_care/index.html
  5. Government of Timor-Leste. Timor-Leste Population and Housing Census. Dili: Government of Timor-Leste; Nov 2022. Available from: https://timor-leste.unfpa.org/sites/default/files/pub-pdf/censuspreliminaryresults2022_4.pdf
  6. World Health Organization Regional Office for South-East Asia (WHO/South-East Asia). Rabies outbreak response: Accelerating a One Health approach in East Nusa Tenggara. New Delhi: WHO/South-East Asia; 18 Oct 2023. Available from https://www.who.int/indonesia/news/detail/18-10-2023-rabies-outbreak-response--accelerating-a-one-health-approach-in-east-nusa-tenggara
  7. Timor-Leste News Agency (Tatoli). Anti-rabies vaccine administered to 57% of registered dogs. Dili: Tatoli; 9 Apr 2024. Available from: https://en.tatoli.tl/2024/04/09/anti-rabies-vaccine-administered-to-57-of-registered-dogs/19/
  8. Instituto Nasional de Saude Publica Timor-Leste (INSPTL). Integrated Disease Surveillance and Response. Dili: INSPTL; Sep 2022. Available from https://ins.gov.tl/wp-content/uploads/2024/01/Integrated-Disease-Surveillance-and-Response-IDSR-1.pdf
  9. Instituto Nasional de Saude Publica Timor-Leste (INSPTL). Guidelines for responding to dog bites in Timor-Leste including pre- and post-exposure rabies prophylaxis. Dili: INSPTL; Dec 2023. Available from https://ins.gov.tl/wp-content/uploads/2024/01/Guidelines-for-Responding-to-Dog-bites-in-Timor-Leste-Including-Pre-and-Post-Exposure-Rabies-Prophylaxis.pdf
  10. Nadin-Davis SA, Sheen M, Wandeler AI. Development of real-time reverse transcriptase polymerase chain reaction methods for human rabies diagnosis. J Med Virol. 2009;81(8):1484-97.  https://doi.org/10.1002/jmv.21547  PMID: 19551825 
  11. Mani RS, Madhusudana SN, Mahadevan A, Reddy V, Belludi AY, Shankar SK. Utility of real-time Taqman PCR for antemortem and postmortem diagnosis of human rabies. J Med Virol. 2014;86(10):1804-12.  https://doi.org/10.1002/jmv.23814  PMID: 24136727 
The first confirmed human case of rabies, Timor-Leste, 2024
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Marcelo+Amaral+Mali&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Amaral Mali Marcelo</a>, <a href="/search?value1=Filipe+de+Neri+Machado&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Machado Filipe de Neri</a>, <a href="/search?value1=Filomeno+Pinto+Moniz&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Moniz Filomeno Pinto</a>, <a href="/search?value1=Frederico+Bosco+Alves+dos+Santos&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bosco Alves dos Santos Frederico</a>, <a href="/search?value1=Perpetua+Ana+Mery+Estela+Laot&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Laot Perpetua Ana Mery Estela</a>, <a href="/search?value1=Ari+Jayanti+Pereira+Tilman&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pereira Tilman Ari Jayanti</a>, <a href="/search?value1=Tanizio+Ebryes+Florindo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Florindo Tanizio Ebryes</a>, <a href="/search?value1=Cristovao+de+Alexandria+Barros&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Barros Cristovao de Alexandria</a>, <a href="/search?value1=Adriano+Barbosa&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Barbosa Adriano</a>, <a href="/search?value1=Jose+A+Oliveira+Lima&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Oliveira Lima Jose A</a>, <a href="/search?value1=Joao+Paulo+Goncalves&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Goncalves Joao Paulo</a>, <a href="/search?value1=Francisco+Borges&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Borges Francisco</a>, <a href="/search?value1=Elisabeth+Hornay&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hornay Elisabeth</a>, <a href="/search?value1=Joanico+Moises&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Moises Joanico</a>, <a href="/search?value1=Osmenia+de+Jesus+Neto&option1=author&noRedirect=true" class="nonDisambigAuthorLink">de Jesus Neto Osmenia</a>, <a href="/search?value1=Liliana+Varela&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Varela Liliana</a>, <a href="/search?value1=Agapito+da+Costa&option1=author&noRedirect=true" class="nonDisambigAuthorLink">da Costa Agapito</a>, <a href="/search?value1=Anthony+DK+Draper&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Draper Anthony DK</a>, <a href="/search?value1=Joshua+R+Francis&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Francis Joshua R</a>, <a href="/search?value1=Merita+Antonio+A+Monteiro&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Monteiro Merita Antonio A</a></span>. The first confirmed human case of rabies, Timor-Leste, 2024. <a href="/content/ecdc">Euro Surveill.</a> 2024;29(18):pii=2400241. <a href="https://doi.org/10.2807/1560-7917.ES.2024.29.18.2400241" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2024.29.18.2400241</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 22 Apr 2024;&nbsp;&nbsp; <span class="generated">Accepted</span>: 26 Apr 2024 </span> </p>
/content/10.2807/1560-7917.ES.2024.29.18.2400241
/content/10.2807/1560-7917.ES.2024.29.18.2400241
Loading

Data & Media loading...

Submit comment
Close
Comment moderation successfully completed
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error