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Ongoing mpox outbreak in Kamituga, South Kivu province, associated with monkeypox virus of a novel Clade I sub-lineage, Democratic Republic of the Congo, 2024
- Leandre Murhula Masirika1,2 , Jean Claude Udahemuka3,4 , Leonard Schuele5 , Pacifique Ndishimye4,6,7 , Saria Otani8 , Justin Bengehya Mbiribindi9 , Jean M. Marekani10 , Léandre Mutimbwa Mambo11 , Nadine Malyamungu Bubala12 , Marjan Boter5 , David F. Nieuwenhuijse5 , Trudie Lang13 , Ernest Balyahamwabo Kalalizi2 , Jean Pierre Musabyimana4,14 , Frank M. Aarestrup8 , Marion Koopmans5 , Bas B. Oude Munnink5,* , Freddy Belesi Siangoli9,*
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View Affiliations Hide AffiliationsAffiliations: 1 Centre de Recherche en Sciences Naturelles de Lwiro, DS Bukavu, South Kivu, Bukavu, Democratic Republic of the Congo 2 SaBio Instituto de Investigación en Recursos Cinegéticos IREC (Universidad de Castilla-La Mancha & CSIC), Ciudad Real, Spain 3 Department of Veterinary Medicine, University of Rwanda, Nyagatare, Rwanda 4 Stansile Research Organization, Kigali, Rwanda 5 Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands 6 Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada 7 Research and Innovation Centre, African Institute for Mathematical Sciences, Kigali, Rwanda 8 Research Group for Genomic Epidemiology, National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark 9 Division Provinciale de la Santé, South Kivu, Bukavu, Democratic Republic of the Congo 10 Unit of Animal Production and Health, Nature Conservation and Development, Department of Biology, Faculty of Science, University of Kinshasa, Kinshasa, Democratic Republic of the Congo 11 Zone de Santé de Kamituga, Kamituga, South Kivu, Bukavu, Democratic Republic of the Congo 12 Hôpital Général de Référence de Kamituga, South Kivu, Bukavu, Democratic Republic of the Congo 13 The Global Health Network, Oxford University, Oxford, United Kingdom 14 Research, innovation and data science division, Rwanda Biomedical Center, Kigali, Rwanda * These authors contributed equallyCorrespondence:Leandre Murhulaleandremurhula gmail.com
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Citation style for this article: Masirika Leandre Murhula, Udahemuka Jean Claude, Schuele Leonard, Ndishimye Pacifique, Otani Saria, Mbiribindi Justin Bengehya, Marekani Jean M., Mambo Léandre Mutimbwa, Bubala Nadine Malyamungu, Boter Marjan, Nieuwenhuijse David F., Lang Trudie, Kalalizi Ernest Balyahamwabo, Musabyimana Jean Pierre, Aarestrup Frank M., Koopmans Marion, Oude Munnink Bas B. , Siangoli Freddy Belesi. Ongoing mpox outbreak in Kamituga, South Kivu province, associated with monkeypox virus of a novel Clade I sub-lineage, Democratic Republic of the Congo, 2024. Euro Surveill. 2024;29(11):pii=2400106. https://doi.org/10.2807/1560-7917.ES.2024.29.11.2400106 Received: 14 Feb 2024; Accepted: 13 Mar 2024
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Abstract
Since the beginning of 2023, the number of people with suspected monkeypox virus (MPXV) infection have sharply increased in the Democratic Republic of the Congo (DRC). We report near-to-complete MPXV genome sequences derived from six cases from the South Kivu province. Phylogenetic analyses reveal that the MPXV affecting the cases belongs to a novel Clade I sub-lineage. The outbreak strain genome lacks the target sequence of the probe and primers of a commonly used Clade I-specific real-time PCR.
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This work is licensed under a Creative Commons Attribution 4.0 International License.
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2024-03-14
2024-11-21
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2024.29.11.2400106
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Ongoing mpox outbreak in Kamituga, South Kivu province, associated with monkeypox virus of a novel Clade I sub-lineage, Democratic Republic of the Congo, 2024
<p class="citation">
<span>Citation style for this article:</span>
<span class="meta-value authors">
<a href="/search?value1=Leandre+Murhula+Masirika&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Masirika Leandre Murhula</a>,
<a href="/search?value1=Jean+Claude+Udahemuka&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Udahemuka Jean Claude</a>,
<a href="/search?value1=Leonard+Schuele&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Schuele Leonard</a>,
<a href="/search?value1=Pacifique+Ndishimye&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ndishimye Pacifique</a>,
<a href="/search?value1=Saria+Otani&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Otani Saria</a>,
<a href="/search?value1=Justin+Bengehya+Mbiribindi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mbiribindi Justin Bengehya</a>,
<a href="/search?value1=Jean+M.+Marekani&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Marekani Jean M.</a>,
<a href="/search?value1=L%C3%A9andre+Mutimbwa+Mambo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mambo Léandre Mutimbwa</a>,
<a href="/search?value1=Nadine+Malyamungu+Bubala&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bubala Nadine Malyamungu</a>,
<a href="/search?value1=Marjan+Boter&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Boter Marjan</a>,
<a href="/search?value1=David+F.+Nieuwenhuijse&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nieuwenhuijse David F.</a>,
<a href="/search?value1=Trudie+Lang&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lang Trudie</a>,
<a href="/search?value1=Ernest+Balyahamwabo+Kalalizi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kalalizi Ernest Balyahamwabo</a>,
<a href="/search?value1=Jean+Pierre+Musabyimana&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Musabyimana Jean Pierre</a>,
<a href="/search?value1=Frank+M.+Aarestrup&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Aarestrup Frank M.</a>,
<a href="/search?value1=Marion+Koopmans&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Koopmans Marion</a>,
<a href="/search?value1=Bas+B.++Oude+Munnink&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Oude Munnink Bas B. </a>,
<a href="/search?value1=Freddy+Belesi+Siangoli&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Siangoli Freddy Belesi</a></span>.
Ongoing mpox outbreak in Kamituga, South Kivu province, associated with monkeypox virus of a novel Clade I sub-lineage, Democratic Republic of the Congo, 2024.
<a href="/content/ecdc">Euro Surveill.</a> 2024;29(11):pii=2400106.
<a href="https://doi.org/10.2807/1560-7917.ES.2024.29.11.2400106" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2024.29.11.2400106</a>
<span class="ES_Article_citation">
<span class="generated">Received</span>: 14 Feb 2024;
<span class="generated">Accepted</span>: 13 Mar 2024
</span>
</p>
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