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Abstract

The SARS-CoV-2 BA.2.86 Omicron subvariant was first detected in wastewater in Sweden in week 31 2023, using 21 highly specific markers from the 50 investigated. We report BA.2.86’s introduction and subsequent spread to all 14 regions performing wastewater sampling, and on 70 confirmed COVID-19 cases, along with the emergence of sublineages JN.1 and JN.2. Further, we investigated two novel mutations defining the unique BA.2.86 branching in Sweden. Our integrated approach enabled variant tracking, offering evidence for well-informed public health interventions.

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/content/10.2807/1560-7917.ES.2023.28.46.2300595
2023-11-16
2024-11-21
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2023.28.46.2300595
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Early detection of the emerging SARS-CoV-2 BA.2.86 lineage through integrated genomic surveillance of wastewater and COVID-19 cases in Sweden, weeks 31 to 38 2023
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Carmen+Espinosa-Gongora&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Espinosa-Gongora Carmen</a>, <a href="/search?value1=Carlo+Berg&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Berg Carlo</a>, <a href="/search?value1=Moa+Rehn&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rehn Moa</a>, <a href="/search?value1=Javier+Edo+Varg&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Varg Javier Edo</a>, <a href="/search?value1=Lena+Dillner&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Dillner Lena</a>, <a href="/search?value1=Neus+Latorre-Margalef&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Latorre-Margalef Neus</a>, <a href="/search?value1=Anna+J+Sz%C3%A9kely&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Székely Anna J</a>, <a href="/search?value1=Emmi+Andersson&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Andersson Emmi</a>, <a href="/search?value1=Elin+Movert&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Movert Elin</a></span>. Early detection of the emerging SARS-CoV-2 BA.2.86 lineage through integrated genomic surveillance of wastewater and COVID-19 cases in Sweden, weeks 31 to 38 2023. <a href="/content/ecdc">Euro Surveill.</a> 2023;28(46):pii=2300595. <a href="https://doi.org/10.2807/1560-7917.ES.2023.28.46.2300595" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2023.28.46.2300595</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 27 Oct 2023;&nbsp;&nbsp; <span class="generated">Accepted</span>: 15 Nov 2023 </span> </p>
/content/10.2807/1560-7917.ES.2023.28.46.2300595
/content/10.2807/1560-7917.ES.2023.28.46.2300595
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