1887
  1. Home
  2. Eurosurveillance
  3. Volume 28, Issue 37, 14/Sep/2023
  4. Article
Rapid communication Open Access
Like 0
Download

Abstract

In August 2023, six locally acquired dengue virus 1 infections were detected in Lodi province, Lombardy Region, in northern Italy, where the vector is present. Four cases were hospitalised, none died. The viruses clustered with Peruvian and Brazilian strains collected between 2021 and 2023. This preliminary report highlights the importance of continued integrated surveillance of imported vector-borne virus infections and the potential for tropical disease outbreaks in highly populated regions of northern Italy where competent vectors are present.

© Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Loading

Article metrics loading...

/content/10.2807/1560-7917.ES.2023.28.37.2300471
2023-09-14
2024-11-24
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2023.28.37.2300471
Loading
Loading full text...

Full text loading...

/deliver/fulltext/eurosurveillance/28/37/eurosurv-28-37-1.html?itemId=/content/10.2807/1560-7917.ES.2023.28.37.2300471&mimeType=html&fmt=ahah

References

  1. Bhatt S, Gething PW, Brady OJ, Messina JP, Farlow AW, Moyes CL, et al. The global distribution and burden of dengue. Nature. 2013;496(7446):504-7.  https://doi.org/10.1038/nature12060  PMID: 23563266 
  2. Wilder-Smith A, Ooi EE, Horstick O, Wills B. Dengue. Lancet. 2019;393(10169):350-63.  https://doi.org/10.1016/S0140-6736(18)32560-1  PMID: 30696575 
  3. La Ruche G, Souarès Y, Armengaud A, Peloux-Petiot F, Delaunay P, Desprès P, et al. First two autochthonous dengue virus infections in metropolitan France, September 2010. Euro Surveill. 2010;15(39):19676.  https://doi.org/10.2807/ese.15.39.19676-en  PMID: 20929659 
  4. Gjenero-Margan I, Aleraj B, Krajcar D, Lesnikar V, Klobučar A, Pem-Novosel I, et al. Autochthonous dengue fever in Croatia, August-September 2010. Euro Surveill. 2011;16(9):19805.  https://doi.org/10.2807/ese.16.09.19805-en  PMID: 21392489 
  5. Alves MJ, Fernandes PL, Amaro F, Osório H, Luz T, Parreira P, et al. Clinical presentation and laboratory findings for the first autochthonous cases of dengue fever in Madeira Island, Portugal, October 2012. Euro Surveill. 2013;18(6):20398.  https://doi.org/10.2807/ese.18.06.20398-en  PMID: 23410256 
  6. Lazzarini L, Barzon L, Foglia F, Manfrin V, Pacenti M, Pavan G, et al. First autochthonous dengue outbreak in Italy, August 2020. Euro Surveill. 2020;25(36):2001606.  https://doi.org/10.2807/1560-7917.ES.2020.25.36.2001606  PMID: 32914745 
  7. Navero-Castillejos J, Benitez R, Torner N, Muñoz J, Camprubí-Ferrer D, Peiró-Mestres A, et al. Molecular characterization of imported and autochthonous Dengue in northeastern Spain. Viruses. 2021;13(10):1910.  https://doi.org/10.3390/v13101910  PMID: 34696340 
  8. Scaramozzino N, Crance JM, Jouan A, DeBriel DA, Stoll F, Garin D. Comparison of flavivirus universal primer pairs and development of a rapid, highly sensitive heminested reverse transcription-PCR assay for detection of flaviviruses targeted to a conserved region of the NS5 gene sequences. J Clin Microbiol. 2001;39(5):1922-7.  https://doi.org/10.1128/JCM.39.5.1922-1927.2001  PMID: 11326014 
  9. Linke S, Ellerbrok H, Niedrig M, Nitsche A, Pauli G. Detection of West Nile virus lineages 1 and 2 by real-time PCR. J Virol Methods. 2007;146(1-2):355-8.  https://doi.org/10.1016/j.jviromet.2007.05.021  PMID: 17604132 
  10. Huhtamo E, Hasu E, Uzcátegui NY, Erra E, Nikkari S, Kantele A, et al. Early diagnosis of dengue in travelers: comparison of a novel real-time RT-PCR, NS1 antigen detection and serology. J Clin Virol. 2010;47(1):49-53.  https://doi.org/10.1016/j.jcv.2009.11.001  PMID: 19963435 
  11. Piralla A, Borghesi A, Di Comite A, Giardina F, Ferrari G, Zanette S, et al. Fulminant echovirus 11 hepatitis in male non-identical twins in northern Italy, April 2023. Euro Surveill. 2023;28(24):2300289.  https://doi.org/10.2807/1560-7917.ES.2023.28.24.2300289  PMID: 37318763 
  12. Borges V, Pinheiro M, Pechirra P, Guiomar R, Gomes JP. INSaFLU: an automated open web-based bioinformatics suite "from-reads" for influenza whole-genome-sequencing-based surveillance. Genome Med. 2018;10(1):46.  https://doi.org/10.1186/s13073-018-0555-0  PMID: 29954441 
  13. Minh BQ, Schmidt HA, Chernomor O, Schrempf D, Woodhams MD, von Haeseler A, et al. IQ-TREE 2: New models and efficient methods for phylogenetic inference in the genomic era. Mol Biol Evol. 2020;37(5):1530-4.  https://doi.org/10.1093/molbev/msaa015  PMID: 32011700 
  14. European Commission (EC). Commission Implementing Decision (EU) 2018/945 of 22 June 2018 on the communicable diseases and related special health issues to be covered by epidemiological surveillance as well as relevant case definitions. Brussels: EC; 2018. Available from: https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32018D0945&from=EN#page=18
  15. Italian Ministry of Health. Piano Nazionale di prevenzione, sorveglianza e risposta alle Arbovirosi (PNA) 2020-2025. [National plan for prevention, surveillance and response to arboviruses (2020-2025)]. Rome: Ministry of Health; 2019. Italian. Available from: https://www.salute.gov.it/imgs/C_17_pubblicazioni_2947_allegato.pdf
  16. Becker N, Petric D, Zgomba M, Boase C, Madon M, Dahl C, et al. Mosquitoes and their control. Berlin, Heidelberg: Springer; 2010. Available from: https://link.springer.com/book/10.1007/978-3-540-92874-4
  17. Malavige GN, Fernando S, Fernando DJ, Seneviratne SL. Dengue viral infections. Postgrad Med J. 2004;80(948):588-601.  https://doi.org/10.1136/pgmj.2004.019638  PMID: 15466994 
  18. Gubler DJ. Epidemic dengue/dengue hemorrhagic fever as a public health, social and economic problem in the 21st century. Trends Microbiol. 2002;10(2):100-3.  https://doi.org/10.1016/S0966-842X(01)02288-0  PMID: 11827812 
  19. Cochet A, Calba C, Jourdain F, Grard G, Durand GA, Guinard A, et al. Autochthonous dengue in mainland France, 2022: geographical extension and incidence increase. Euro Surveill. 2022;27(44):2200818.  https://doi.org/10.2807/1560-7917.ES.2022.27.44.2200818  PMID: 36330819 
  20. Romi R. History and updating on the spread of Aedes albopictus in Italy. Parassitologia. 1995;37(2-3):99-103. PMID: 8778671 
  21. Romi R. [Aedes albopictus in Italy: an underestimated health problem]. Ann Ist Super Sanita. 2001;37(2):241-7. Italian. PMID:11758282 PMID: 11758282 
  22. Barzon L, Gobbi F, Capelli G, Montarsi F, Martini S, Riccetti S, et al. Autochthonous dengue outbreak in Italy 2020: clinical, virological and entomological findings. J Travel Med. 2021;28(8):taab130.  https://doi.org/10.1093/jtm/taab130  PMID: 34409443 
  23. European Centre for Disease Prevention and Control (ECDC). Communicable disease threats report. Week 36, 3-9 September 2023. Stockholm: ECDC; 2023. Available from: https://www.ecdc.europa.eu/sites/default/files/documents/Communicable_disease_threats_report_3-9_September_2023_week_36.pdf
  24. Auerswald H, de Jesus A, Seixas G, Nazareth T, In S, Mao S, et al. First dengue virus seroprevalence study on Madeira Island after the 2012 outbreak indicates unreported dengue circulation. Parasit Vectors. 2019;12(1):103.  https://doi.org/10.1186/s13071-019-3357-3  PMID: 30867031 
  25. Rovida F, Percivalle E, Campanini G, Piralla A, Novati S, Muscatello A, et al. Viremic dengue virus infections in travellers: potential for local outbreak in Northern Italy. J Clin Virol. 2011;50(1):76-9.  https://doi.org/10.1016/j.jcv.2010.09.015  PMID: 21056002 
Preliminary results on an autochthonous dengue outbreak in Lombardy Region, Italy, August 2023
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Irene+Cassaniti&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cassaniti Irene</a>, <a href="/search?value1=Guglielmo+Ferrari&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ferrari Guglielmo</a>, <a href="/search?value1=Sabrina+Senatore&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Senatore Sabrina</a>, <a href="/search?value1=Eva+Rossetti&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rossetti Eva</a>, <a href="/search?value1=Francesco+Defilippo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Defilippo Francesco</a>, <a href="/search?value1=Manuel+Maffeo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Maffeo Manuel</a>, <a href="/search?value1=Luigi+Vezzosi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Vezzosi Luigi</a>, <a href="/search?value1=Giulia+Campanini&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Campanini Giulia</a>, <a href="/search?value1=Antonella+Sarasini&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sarasini Antonella</a>, <a href="/search?value1=Stefania+Paolucci&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Paolucci Stefania</a>, <a href="/search?value1=Antonio+Piralla&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Piralla Antonio</a>, <a href="/search?value1=Davide+Lelli&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lelli Davide</a>, <a href="/search?value1=Ana+Moreno&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Moreno Ana</a>, <a href="/search?value1=Maira+Bonini&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bonini Maira</a>, <a href="/search?value1=Marcello+Tirani&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Tirani Marcello</a>, <a href="/search?value1=Lorenzo+Cerutti&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cerutti Lorenzo</a>, <a href="/search?value1=Stefano+Paglia&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Paglia Stefano</a>, <a href="/search?value1=Angelo+Regazzetti&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Regazzetti Angelo</a>, <a href="/search?value1=Marco+Farioli&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Farioli Marco</a>, <a href="/search?value1=Antonio+Lavazza&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lavazza Antonio</a>, <a href="/search?value1=Marino+Faccini&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Faccini Marino</a>, <a href="/search?value1=Francesca+Rovida&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rovida Francesca</a>, <a href="/search?value1=Danilo+Cereda&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cereda Danilo</a>, <a href="/search?value1=Fausto+Baldanti&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Baldanti Fausto</a>, <a href="/search?value1=Lombardy+Dengue+network&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lombardy Dengue network</a></span>. Preliminary results on an autochthonous dengue outbreak in Lombardy Region, Italy, August 2023. <a href="/content/ecdc">Euro Surveill.</a> 2023;28(37):pii=2300471. <a href="https://doi.org/10.2807/1560-7917.ES.2023.28.37.2300471" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2023.28.37.2300471</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 04 Sept 2023;&nbsp;&nbsp; <span class="generated">Accepted</span>: 13 Sept 2023 </span> </p>
/content/10.2807/1560-7917.ES.2023.28.37.2300471
/content/10.2807/1560-7917.ES.2023.28.37.2300471
Loading

Data & Media loading...

Submit comment
Close
Comment moderation successfully completed
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error