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Abstract

Background

In 2020, due to the COVID-19 pandemic, the European Centre for Disease Prevention and Control (ECDC) accelerated development of European-level severe acute respiratory infection (SARI) surveillance.

Aim

We aimed to establish SARI surveillance in one Irish hospital as part of a European network E-SARI-NET.

Methods

We used routine emergency department records to identify cases in one adult acute hospital. The SARI case definition was adapted from the ECDC clinical criteria for a possible COVID-19 case. Clinical data were collected using an online questionnaire. Cases were tested for SARS-CoV-2, influenza and respiratory syncytial virus (RSV), including whole genome sequencing (WGS) on SARS-CoV-2 RNA-positive samples and viral characterisation/sequencing on influenza RNA-positive samples. Descriptive analysis was conducted for SARI cases hospitalised between July 2021 and April 2022.

Results

Overall, we identified 437 SARI cases, the incidence ranged from two to 28 cases per week (0.7–9.2/100,000 hospital catchment population). Of 431 cases tested for SARS-CoV-2 RNA, 226 (52%) were positive. Of 349 (80%) cases tested for influenza and RSV RNA, 15 (4.3%) were positive for influenza and eight (2.3%) for RSV. Using WGS, we identified Delta- and Omicron-dominant periods. The resource-intensive nature of manual clinical data collection, specimen management and laboratory supply shortages for influenza and RSV testing were challenging.

Conclusion

We successfully established SARI surveillance as part of E-SARI-NET. Expansion to additional sentinel sites is planned following formal evaluation of the existing system. SARI surveillance requires multidisciplinary collaboration, automated data collection where possible, and dedicated personnel resources, including for specimen management.

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This work is licensed under a Creative Commons Attribution 4.0 International License.
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/content/10.2807/1560-7917.ES.2023.28.23.2200740
2023-06-08
2024-11-21
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2023.28.23.2200740
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Establishing severe acute respiratory infection (SARI) surveillance in a sentinel hospital, Ireland, 2021 to 2022
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Melissa+Brady&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Brady Melissa</a>, <a href="/search?value1=Roisin+Duffy&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Duffy Roisin</a>, <a href="/search?value1=Lisa+Domegan&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Domegan Lisa</a>, <a href="/search?value1=Abigail+Salmon&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Salmon Abigail</a>, <a href="/search?value1=Binita+Maharjan&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Maharjan Binita</a>, <a href="/search?value1=Cathal+O%26apos%3BBroin&option1=author&noRedirect=true" class="nonDisambigAuthorLink">O&apos;Broin Cathal</a>, <a href="/search?value1=Charlene+Bennett&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bennett Charlene</a>, <a href="/search?value1=James+Christle&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Christle James</a>, <a href="/search?value1=Jeff+Connell&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Connell Jeff</a>, <a href="/search?value1=Laura+Feeney&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Feeney Laura</a>, <a href="/search?value1=Nadra+Nurdin&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nurdin Nadra</a>, <a href="/search?value1=Patrick+Mallon&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mallon Patrick</a>, <a href="/search?value1=Peter+Doran&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Doran Peter</a>, <a href="/search?value1=Rosa+McNamara&option1=author&noRedirect=true" class="nonDisambigAuthorLink">McNamara Rosa</a>, <a href="/search?value1=Sarah+O%26apos%3BGrady&option1=author&noRedirect=true" class="nonDisambigAuthorLink">O&apos;Grady Sarah</a>, <a href="/search?value1=Sinead+McDermott&option1=author&noRedirect=true" class="nonDisambigAuthorLink">McDermott Sinead</a>, <a href="/search?value1=Naomi+Petty-Saphon&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Petty-Saphon Naomi</a>, <a href="/search?value1=Joan+O%E2%80%99Donnell&option1=author&noRedirect=true" class="nonDisambigAuthorLink">O’Donnell Joan</a></span>. Establishing severe acute respiratory infection (SARI) surveillance in a sentinel hospital, Ireland, 2021 to 2022. <a href="/content/ecdc">Euro Surveill.</a> 2023;28(23):pii=2200740. <a href="https://doi.org/10.2807/1560-7917.ES.2023.28.23.2200740" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2023.28.23.2200740</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 10 Sept 2022;&nbsp;&nbsp; <span class="generated">Accepted</span>: 26 Feb 2023 </span> </p>
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