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Abstract

Background

The burden of Legionnaires’ disease (LD) in the European Union/European Economic Area (EU/EEA) has increased during the last decade, with notification rates increasing from 1.2 to 1.4/100,000 population in 2012–16, to 1.8–2.2 within 2017–19.

Aim

To measure weekly excess cases during 2017–19 based on previous trends and determine whether a significant change in trend occurred, and to examine any differences in age, sex or level of imported infections.

Methods

We collated 2012–19 annual surveillance data from The European Surveillance System (TESSy) reported by EU/EEA countries. A retrospective prediction by a dynamic regression model was created from 2012–16 data to assess excess cases in 2017–19. Interrupted time series (ITS) analysis was performed to determine if a significant change in trend occurred in 2017–19 compared with the previous 5 years.

Results

We found a 33.9% increase in cases in 2017–19 compared with the number predicted. The ITS also found a significant trend increase in 2017–19 compared with 2012–16. A significant trend increase was observed from 2017 most strongly among older age groups (> 60 years) and non-imported cases.

Conclusion

Our study showed a significant increasing trend in LD cases in the EU/EEA during 2017–19 compared with the previous 5 years. The distribution of cases per week suggests an overall amplification of the seasonal trends. These findings underscore that LD continues to be an infectious disease of public health concern in the EU/EEA, warranting further research into determinants of the increase.

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This work is licensed under a Creative Commons Attribution 4.0 International License.
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/content/10.2807/1560-7917.ES.2023.28.11.2200114
2023-03-16
2024-11-22
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2023.28.11.2200114
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Legionnaires’ disease in the EU/EEA*: increasing trend from 2017 to 2019
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Jonas+Samuelsson&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Samuelsson Jonas</a>, <a href="/search?value1=Lara+Payne+Hallstr%C3%B6m&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Payne Hallström Lara</a>, <a href="/search?value1=Gaetano+Marrone&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Marrone Gaetano</a>, <a href="/search?value1=Joana+Gomes+Dias&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gomes Dias Joana</a></span>. Legionnaires’ disease in the EU/EEA*: increasing trend from 2017 to 2019. <a href="/content/ecdc">Euro Surveill.</a> 2023;28(11):pii=2200114. <a href="https://doi.org/10.2807/1560-7917.ES.2023.28.11.2200114" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2023.28.11.2200114</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 26 Jan 2022;&nbsp;&nbsp; <span class="generated">Accepted</span>: 26 Jan 2023 </span> </p>
/content/10.2807/1560-7917.ES.2023.28.11.2200114
/content/10.2807/1560-7917.ES.2023.28.11.2200114
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