1887
  1. Home
  2. Eurosurveillance
  3. Volume 27, Issue 6, 10/Feb/2022
  4. Article
Rapid communication Open Access
Like 0
Download

Abstract

The SARS-CoV-2 Omicron variant has a growth advantage over the Delta variant because of higher transmissibility, immune evasion or shorter serial interval. Using S gene target failure (SGTF) as indication for Omicron BA.1, we identified 908 SGTF and 1,621 non-SGTF serial intervals in the same period. Within households, the mean serial interval for SGTF cases was 0.2–0.6 days shorter than for non-SGTF cases. This suggests that the growth advantage of Omicron is partly due to a shorter serial interval.

© Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Loading

Article metrics loading...

/content/10.2807/1560-7917.ES.2022.27.6.2200042
2022-02-10
2024-12-21
/content/10.2807/1560-7917.ES.2022.27.6.2200042
Loading
Loading full text...

Full text loading...

/deliver/fulltext/eurosurveillance/27/6/eurosurv-27-6-1.html?itemId=/content/10.2807/1560-7917.ES.2022.27.6.2200042&mimeType=html&fmt=ahah

References

  1. World Health Organization (WHO). Tracking SARS-CoV-2 variants. Geneva: WHO. [Accessed: 8 Feb 2022]. Available from: https://www.who.int/en/activities/tracking-SARS-CoV-2-variants
  2. Ito K, Piantham C, Nishiura H. Relative instantaneous reproduction number of Omicron SARS-CoV-2 variant with respect to the Delta variant in Denmark. J Med Virol. 2021. PMID: 34967453 
  3. Cele S, Jackson L, Khan K, Khoury DS, Moyo-Gwete T, Tegally H, et al. SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection. medRxiv. 2021.12.08.21267417 https://doi.org/10.1101/2021.12.08.21267417 
  4. Eggink D, Andeweg SP, Vennema H, van Maarseveen N, Vermaas K, Vlaemynck B, et al. Increased risk of infection with SARS-CoV-2 Omicron BA.1 compared with Delta in vaccinated and previously infected individuals, the Netherlands, 22 November 2021 to 19 January 2022. Euro Surveill. 2022;27(4):2101196.  https://doi.org/10.2807/1560-7917.ES.2022.27.4.2101196  PMID: 35086609 
  5. Wilhelm A, Widera M, Grikscheit K, Toptan T, Schenk B, Pallas C, et al. Reduced neutralization of SARS-CoV-2 Omicron variant by vaccine sera and monoclonal antibodies. medRxiv. 2021.12.07.21267432 https://doi.org/10.1101/2021.12.07.21267432 
  6. Peacock TP, Brown JC, Zhou J, Thakur N, Newman J, Kugathasan R, et al. The SARS-CoV-2 variant, Omicron, shows rapid replication in human primary nasal epithelial cultures and efficiently uses the endosomal route of entry. bioRxiv. 2021.12.31.474653 . https://doi.org/10.1101/2021.12.31.474653 
  7. Rijksinstituut voor Volksgezondheid en Milieu (RIVM). Varianten van het coronavirus SARS-CoV-2. [Variants of the coronavirus SARS-CoV-2]. Bilthoven: RIVM. [Accessed: 27 Jan 2022]. Dutch. Available from: https://www.rivm.nl/coronavirus-covid-19/virus/varianten
  8. Centraal Bureau voor de Statistiek (CBS) Transmissieparen adres, werkgever en school, jan-sep 2021. [Transmission pairs' address, employer and school, Jan-Sep 2021]. Den Haag: CBS, 2021. Available from: https://www.cbs.nl/nl-nl/maatwerk/2021/49/transmissieparen-adres-werkgever-en-school-jan-sep-2021
  9. Backer JA, Klinkenberg D, Wallinga J. Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travellers from Wuhan, China, 20-28 January 2020. Euro Surveill. 2020;25(5).  https://doi.org/10.2807/1560-7917.ES.2020.25.5.2000062  PMID: 32046819 
  10. Kim D, Jo J, Lim J-S, Ryu S. Serial interval and basic reproduction number of SARS-CoV-2 Omicron variant in South Korea. medRxiv. 2021.12.25.21268301 . https://doi.org/10.1101/2021.12.25.21268301 
  11. Lee JJ, Choe YJ, Jeong H, Kim M, Kim S, Yoo H, et al. Importation and transmission of SARS-CoV-2 B.1.1.529 (Omicron) variant of concern in Korea, November 2021. J Korean Med Sci. 2021;36(50):e346.  https://doi.org/10.3346/jkms.2021.36.e346  PMID: 34962117 
  12. Kremer C, Braeye T, Proesmans K, André E, Torneri A, Hens N. Observed serial intervals of SARS-CoV-2 for the Omicron and Delta variants in Belgium based on contact tracing data, 19 November to 31 December 2021. medRxiv. 2022.01.28.22269756 .  https://doi.org/10.1101/2022.01.28.22269756 
  13. Brandal LT, MacDonald E, Veneti L, Ravlo T, Lange H, Naseer U, et al. Outbreak caused by the SARS-CoV-2 Omicron variant in Norway, November to December 2021. Euro Surveill. 2021;26(50).  https://doi.org/10.2807/1560-7917.ES.2021.26.50.2101147  PMID: 34915975 
  14. Jansen L, Tegomoh B, Lange K, Showalter K, Figliomeni J, Abdalhamid B, et al. Investigation of a SARS-CoV-2 B.1.1.529 (Omicron) Variant Cluster - Nebraska, November-December 2021. MMWR Morb Mortal Wkly Rep. 2021;70(5152):1782-4.  https://doi.org/10.15585/mmwr.mm705152e3  PMID: 34968376 
  15. Kucharski AJ, Klepac P, Conlan AJK, Kissler SM, Tang ML, Fry H, et al. Effectiveness of isolation, testing, contact tracing, and physical distancing on reducing transmission of SARS-CoV-2 in different settings: a mathematical modelling study. Lancet Infect Dis. 2020;20(10):1151-60.  https://doi.org/10.1016/S1473-3099(20)30457-6  PMID: 32559451 
  16. Kozlov M. Omicron’s feeble attack on the lungs could make it less dangerous. Nature. 2022;601(7892):177.  https://doi.org/10.1038/d41586-022-00007-8  PMID: 34987210 
Shorter serial intervals in SARS-CoV-2 cases with Omicron BA.1 variant compared with Delta variant, the Netherlands, 13 to 26 December 2021
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Jantien+A+Backer&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Backer Jantien A</a>, <a href="/search?value1=Dirk+Eggink&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Eggink Dirk</a>, <a href="/search?value1=Stijn+P+Andeweg&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Andeweg Stijn P</a>, <a href="/search?value1=Irene+K+Veldhuijzen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Veldhuijzen Irene K</a>, <a href="/search?value1=Noortje+van+Maarseveen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">van Maarseveen Noortje</a>, <a href="/search?value1=Klaas+Vermaas&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Vermaas Klaas</a>, <a href="/search?value1=Boris+Vlaemynck&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Vlaemynck Boris</a>, <a href="/search?value1=Raf+Schepers&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Schepers Raf</a>, <a href="/search?value1=Susan+van+den+Hof&option1=author&noRedirect=true" class="nonDisambigAuthorLink">van den Hof Susan</a>, <a href="/search?value1=Chantal+BEM+Reusken&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Reusken Chantal BEM</a>, <a href="/search?value1=Jacco+Wallinga&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Wallinga Jacco</a></span>. Shorter serial intervals in SARS-CoV-2 cases with Omicron BA.1 variant compared with Delta variant, the Netherlands, 13 to 26 December 2021. <a href="/content/ecdc">Euro Surveill.</a> 2022;27(6):pii=2200042. <a href="https://doi.org/10.2807/1560-7917.ES.2022.27.6.2200042" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2022.27.6.2200042</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 13 Jan 2022;&nbsp;&nbsp; <span class="generated">Accepted</span>: 09 Feb 2022 </span> </p>
/content/10.2807/1560-7917.ES.2022.27.6.2200042
/content/10.2807/1560-7917.ES.2022.27.6.2200042
Loading

Data & Media loading...

Supplementary data

Submit comment
Close
Comment moderation successfully completed
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error